Desensitization of functional µ-opioid receptors increases agonist off-rate (Q33742761)

29 July 2017

title

Desensitization of functional µ-opioid receptors increases agonist off-rate (English)

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29 July 2017

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John T Williams

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29 July 2017

publication date

18 April 2014

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29 July 2017

published in

Molecular Pharmacology

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29 July 2017

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29 July 2017

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29 July 2017

page(s)

52-61

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Caged naloxone reveals opioid signaling deactivation kinetics

29 July 2017

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21 June 2018

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Regulation of μ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance.

21 June 2018

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Differentiation of opioid drug effects by hierarchical multi-site phosphorylation

21 June 2018

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GIRK channel modulation by assembly with allosterically regulated RGS proteins

21 June 2018

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μ-Opioid receptor desensitization: homologous or heterologous?

21 June 2018

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Morphine desensitization and cellular tolerance are distinguished in rat locus ceruleus neurons

21 June 2018

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Photoactivatable neuropeptides for spatiotemporally precise delivery of opioids in neural tissue

21 June 2018

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Inactive-state preassembly of Gq-coupled receptors and Gq heterotrimers

21 June 2018

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Recovery from μ-Opioid Receptor Desensitization after Chronic Treatment with Morphine and Methadone

21 June 2018

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21 June 2018

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Buprenorphine is a weak partial agonist that inhibits opioid receptor desensitization.

21 June 2018

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21 June 2018

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21 June 2018

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Signaling through a G Protein-coupled receptor and its corresponding G protein follows a stoichiometrically limited model

21 June 2018

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21 June 2018

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GIRK channel activation involves a local rearrangement of a preformed G protein channel complex

21 June 2018

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Heterotrimeric G proteins precouple with G protein-coupled receptors in living cells

21 June 2018

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Gating properties of GIRK channels activated by Galpha(o)- and Galpha(i)-coupled muscarinic m2 receptors in Xenopus oocytes: the role of receptor precoupling in RGS modulation.

21 June 2018

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Characterization of acute homologous desensitization of mu-opioid receptor-induced currents in locus coeruleus neurones.

21 June 2018

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21 June 2018

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Kinetic evidence for differential agonist and antagonist binding to bovine hippocampal synaptic membrane opioid receptors

21 June 2018

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Multiple agonist-affinity states of opioid receptors: regulation of binding by guanyl nucleotides in guinea pig cortical, NG108-15, and 7315c cell membranes

21 June 2018

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Identification of two C-terminal amino acids, Ser(355) and Thr(357), required for short-term homologous desensitization of mu-opioid receptors

21 June 2018

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Efficacy and Kinetics of Opioid Action on Acutely Dissociated Neurons

30 October 2018

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Opioid desensitization: interactions with G-protein-coupled receptors in the locus coeruleus

30 October 2018

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30 October 2018

Identifiers

DOI

10.1124/MOL.114.092098

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29 July 2017

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29 July 2017

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