Ferrochelatase is a therapeutic target for ocular neovascularization. (Q33749012)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28377496%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

title

Ferrochelatase is a therapeutic target for ocular neovascularization (English)

1 reference

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16 March 2020

1 reference

1 reference

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16 March 2020

Maria B Grant

1 reference

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16 March 2020

Seung-Yong Seo

1 reference

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16 March 2020

author name string

Halesha D Basavarajappa

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16 March 2020

Rania S Sulaiman

1 reference

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16 March 2020

Xiaoping Qi

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16 March 2020

Trupti Shetty

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16 March 2020

Sardar Sheik Pran Babu

1 reference

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16 March 2020

Kamakshi L Sishtla

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16 March 2020

Bit Lee

1 reference

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16 March 2020

Judith Quigley

1 reference

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16 March 2020

Sameerah Alkhairy

1 reference

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16 March 2020

Christian M Briggs

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16 March 2020

Kamna Gupta

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16 March 2020

Buyun Tang

1 reference

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16 March 2020

Mehdi Shadmand

1 reference

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16 March 2020

Michael E Boulton

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16 March 2020

language of work or name

English

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publication date

1 June 2017

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16 March 2020

published in

EMBO Molecular Medicine

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16 March 2020

volume

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16 March 2020

issue

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16 March 2020

page(s)

786-801

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describes a project that uses

16 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5452042/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Design, synthesis and biological evaluation of photoaffinity probes of antiangiogenic homoisoflavonoids.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

A novel small molecule ameliorates ocular neovascularisation and synergises with anti-VEGF therapy

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

A metabolomic perspective of griseofulvin-induced liver injury in mice.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

A Global Map of Lipid-Binding Proteins and Their Ligandability in Cells.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

A Simple Optical Coherence Tomography Quantification Method for Choroidal Neovascularization

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Synthesis and Biological Evaluation of Novel Homoisoflavonoids for Retinal Neovascularization

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Optical coherence tomography enables imaging of tumor initiation in the TAg-RB mouse model of retinoblastoma

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

The chemistry of griseofulvin

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Natural product inhibitors of ocular angiogenesis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Tracking cancer drugs in living cells by thermal profiling of the proteome

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Reliability of the mouse model of choroidal neovascularization induced by laser photocoagulation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

The first synthesis of the antiangiogenic homoisoflavanone, cremastranone

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Synthesis and mechanistic studies of a novel homoisoflavanone inhibitor of endothelial cell growth

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Emerging treatments for wet age-related macular degeneration

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Laser-induced choroidal neovascularization model to study age-related macular degeneration in mice.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Salicylic acid induces mitochondrial injury by inhibiting ferrochelatase heme biosynthesis activity

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Emerging therapies for neovascular age-related macular degeneration: drugs in the pipeline

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

A novel ex vivo murine retina angiogenesis (EMRA) assay.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

One ring to rule them all: trafficking of heme and heme synthesis intermediates in the metazoans

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Preferred therapies for neovascular age-related macular degeneration

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Triptolide directly inhibits dCTP pyrophosphatase.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Ranibizumab versus bevacizumab for the treatment of neovascular age-related macular degeneration

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Ranibizumab Therapy for Neovascular Age-Related Macular Degeneration

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Erythropoietic protoporphyria

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Hepatic damage and oxidative stress induced by Griseofulvin in mice.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Review of the ocular angiogenesis animal models

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Vascular endothelial growth factor in eye disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Inhibition of choroidal neovascularization by homoisoflavanone, a new angiogenesis inhibitor.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Safety and tolerability of oral antifungal agents in the treatment of fungal nail disease: a proven reality

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Heme oxygenase-1 and carbon monoxide in vascular pathobiology: focus on angiogenesis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Erythropoietic protoporphyria with eye complications

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Non-responders to bevacizumab (Avastin) therapy of choroidal neovascular lesions

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Heme: a versatile signaling molecule controlling the activities of diverse regulators ranging from transcription factors to MAP kinases

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Endothelial nitric oxide synthase in vascular disease: from marvel to menace

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Retinal and choroidal angiogenesis: pathophysiology and strategies for inhibition

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Application of 4,5-diaminofluorescein to reliably measure nitric oxide released from endothelial cellsin vitro

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Nitric oxide and angiogenesis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Ferrochelatase at the millennium: structures, mechanisms and [2Fe-2S] clusters

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Accumulation of HIF-1alpha under the influence of nitric oxide.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Ferrochelatase structural mutant (Fechm1Pas) in the house mouse

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Mammalian ferrochelatase. Expression and characterization of normal and two human protoporphyric ferrochelatases

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Increased gene expression for VEGF and the VEGF receptors KDR/Flk and Flt in lungs exposed to acute or to chronic hypoxia. Modulation of gene expression by nitric oxide

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Mechanism of action of antifungal drugs, with special reference to the imidazole derivatives.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Ferrochelatase and N-alkylated porphyrins.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Strain and sex differences in the response of mice to drugs that induce protoporphyria: role of porphyrin biosynthesis and removal

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Erythropoietic protoporphyria in the house mouse. A recessive inherited ferrochelatase deficiency with anemia, photosensitivity, and liver disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Investigation of Specific Binding Proteins to Photoaffinity Linkers for Efficient Deconvolution of Target Protein.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Therapies for neovascular age-related macular degeneration: current approaches and pharmacologic agents in development.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Comparative evaluation of griseofulvin, terbinafine and fluconazole in the treatment of tinea capitis.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Homoisoflavanone inhibits retinal neovascularization through cell cycle arrest with decrease of cdc2 expression.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Anti-angiogenic activity of a homoisoflavanone from Cremastra appendiculata.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5452042

Inhibition of ferrochelatase and accumulation of porphyrins in mouse hepatocyte cultures exposed to porphyrinogenic chemicals

30 October 2018

1 reference

12 December 2020

Griseofulvin levels in stratum corneum. Study after oral administration in man

1 reference

12 December 2020

Experimental griseofulvin porphyria in adult and foetal mice

1 reference

12 December 2020

Hypoxia regulates vascular endothelial growth factor receptor KDR/Flk gene expression through adenosine A2 receptors in retinal capillary endothelial cells

1 reference

12 December 2020

Identifiers

DOI

10.15252/EMMM.201606561

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28377496%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28377496%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

PubMed publication ID

28377496

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28377496%20AND%20SRC:MED&resulttype=core&format=json