Opposing effects of prostaglandin E2 receptors EP3 and EP4 on mouse and human β-cell survival and proliferation (Q33726561)

28 July 2017

title

Opposing effects of prostaglandin E2 receptors EP3 and EP4 on mouse and human β-cell survival and proliferation (English)

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28 July 2017

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Bethany A Carboneau

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28 July 2017

Jack A Allan

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28 July 2017

Shannon E Townsend

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28 July 2017

Michelle E Kimple

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28 July 2017

Richard M Breyer

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28 July 2017

Maureen Gannon

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28 July 2017

publication date

5 April 2017

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28 July 2017

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28 July 2017

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28 July 2017

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28 July 2017

page(s)

548-559

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describes a project that uses

28 July 2017

Cytoscape

1 reference

9 June 2022

https://europepmc.org/search?query=(METHODS:'Cytoscape')

inferred from PubMed Central ID database lookup

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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Research-Focused Isolation of Human Islets From Donors With and Without Diabetes at the Alberta Diabetes Institute IsletCore

14 July 2018

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Structure-activity relationship studies leading to the identification of (2E)-3-[l-[(2,4-dichlorophenyl)methyl]-5-fluoro-3-methyl-lH-indol-7-yl]-N-[(4,5-dichloro-2-thienyl)sulfonyl]-2-propenamide (DG-041), a potent and selective prostanoid EP3 recep

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DG-041 inhibits the EP3 prostanoid receptor--a new target for inhibition of platelet function in atherothrombotic disease

30 October 2018

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30 October 2018

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30 October 2018

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NMDA receptor activation results in PKA- and ERK-dependent Mnk1 activation and increased eIF4E phosphorylation in hippocampal area CA1.

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Inhibition of interleukin-1beta-induced COX-2 and EP3 gene expression by sodium salicylate enhances pancreatic islet beta-cell function

30 October 2018

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Pertussis toxin-sensitive G protein mediation of PGE2 inhibition of cAMP metabolism and phasic glucose-induced insulin secretion in HIT cells

30 October 2018

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12 December 2020

Divergent effects of epinephrine and prostaglandin E2 on glucose-induced insulin secretion from perifused rat islets

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Effect of homologous placental lactogens, prolactins, and growth hormones on islet B-cell division and insulin secretion in rat, mouse, and human islets: implication for placental lactogen regulation of islet function during pregnancy

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Prostaglandin E receptor EP3gamma isoform, with mostly full constitutive Gi activity and agonist-dependent Gs activity

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Interleukin 1-induced prostaglandin E2 accumulation by isolated pancreatic islets

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The prevention of colitis by E Prostanoid receptor 4 agonist through enhancement of epithelium survival and regeneration

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12 December 2020

Prostaglandins inhibit pancreatic beta-cell replication and long-term insulin secretion by pertussis toxin-insensitive mechanisms but do not mediate the actions of interleukin-1 beta

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10.1016/J.MOLMET.2017.04.002

Identifiers

DOI

1 reference

28 July 2017

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28 July 2017

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