Genetic modulation of the interleukin 6 (IL-6) system in patients with advanced gastric cancer: a background for an alternative target therapy. (Q33714950)

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English	Genetic modulation of the interleukin 6 (IL-6) system in patients with advanced gastric cancer: a background for an alternative target therapy.	scientific article

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scholarly article

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19 March 2020

Genetic modulation of the interleukin 6 (IL-6) system in patients with advanced gastric cancer: a background for an alternative target therapy (English)

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19 March 2020

Annamaria Ruzzo

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19 March 2020

Elisa Giacomini

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19 March 2020

Daniele Santini

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19 March 2020

Giuseppe Tonini

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19 March 2020

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19 March 2020

Vincenzo Catalano

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Vincenzo Catalano

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19 March 2020

Emanuele Canestrari

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Emanuele Canestrari

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19 March 2020

Giammaria Fiorentini

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Giammaria Fiorentini

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19 March 2020

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Mauro Magnani

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19 March 2020

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Francesco Graziano

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19 March 2020

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22 May 2014

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19 March 2020

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19 March 2020

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19 March 2020

357

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19 March 2020

A phase I, open-label study of siltuximab, an anti-IL-6 monoclonal antibody, in patients with B-cell non-Hodgkin lymphoma, multiple myeloma, or Castleman disease

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28 July 2018

Cytokine patterns in patients with cancer: a systematic review.

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28 July 2018

Interleukin-6 mediates epithelial-stromal interactions and promotes gastric tumorigenesis

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28 July 2018

Functional IL6R 358Ala allele impairs classical IL-6 receptor signaling and influences risk of diverse inflammatory diseases

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28 July 2018

IL-6 polymorphisms: a useful genetic tool for inflammation research?

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28 July 2018

IL-6 trans-signaling via the soluble IL-6 receptor: importance for the pro-inflammatory activities of IL-6.

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28 July 2018

Targeting interleukin-6: all the way to treat autoimmune and inflammatory diseases

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28 July 2018

Activation of an IL6 inflammatory loop mediates trastuzumab resistance in HER2+ breast cancer by expanding the cancer stem cell population.

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Interleukin-6 signaling pathway in targeted therapy for cancer

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28 July 2018

Targeting the interleukin-6/Jak/stat pathway in human malignancies

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28 July 2018

Hitting a complex target: an update on interleukin-6 trans-signalling

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An intermediate-risk multiple myeloma subgroup is defined by sIL-6r: levels synergistically increase with incidence of SNP rs2228145 and 1q21 amplification

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28 July 2018

A humanized anti-IL-6 antibody (ALD518) in non-small cell lung cancer

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28 July 2018

Differential roles of STAT3 depending on the mechanism of STAT3 activation in gastric cancer cells

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28 July 2018

The pro- and anti-inflammatory properties of the cytokine interleukin-6.

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28 July 2018

IL-6 trans-signaling in formation and progression of malignant ascites in ovarian cancer

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28 July 2018

Prognostic significance of interleukin-6 single nucleotide polymorphism genotypes in neuroblastoma: rs1800795 (promoter) and rs8192284 (receptor).

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28 July 2018

Interleukin-6 induces an epithelial-mesenchymal transition phenotype in human breast cancer cells.

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28 July 2018

Clinical significances of preoperative serum interleukin-6 and C-reactive protein level in operable gastric cancer

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28 July 2018

Host genetic variants in the interleukin-6 promoter predict poor outcome in patients with estrogen receptor-positive, node-positive breast cancer

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28 July 2018

Second-line chemotherapy for patients with advanced gastric cancer: who may benefit?

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28 July 2018

IL-6 induces MUC4 expression through gp130/STAT3 pathway in gastric cancer cell lines

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28 July 2018

sIL-6R: more than an agonist?

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28 July 2018

IL-6 induces AGS gastric cancer cell invasion via activation of the c-Src/RhoA/ROCK signaling pathway

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28 July 2018

Differential regulation of gastric tumor growth by cytokines that signal exclusively through the coreceptor gp130.

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21 January 2018

Interleukin-6 increases vascular endothelial growth factor and angiogenesis in gastric carcinoma

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21 January 2018

Correlation between serum levels of interleukin-6 and vascular endothelial growth factor in gastric carcinoma.

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21 January 2018

Elevated levels of circulating platelet microparticles, VEGF, IL-6 and RANTES in patients with gastric cancer: possible role of a metastasis predictor.

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21 January 2018

Cytokine and cytokine receptor gene polymorphisms and their functionality.

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21 January 2018

Metastatic cells can escape the proapoptotic effects of TNF-α through increased autocrine IL-6/STAT3 signaling

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21 January 2018

Polymorphism in cytokine genes as prognostic markers in Hodgkin's lymphoma.

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21 January 2018

Serum interleukin-6 level but not genotype predicts survival after resection in stages II and III gastric carcinoma.

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Prognostic or predictive plasma cytokines and angiogenic factors for patients treated with pazopanib for metastatic renal-cell cancer: a retrospective analysis of phase 2 and phase 3 trials

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21 January 2018

Vorinostat in advanced prostate cancer patients progressing on prior chemotherapy (National Cancer Institute Trial 6862): trial results and interleukin-6 analysis: a study by the Department of Defense Prostate Cancer Clinical Trial Consortium [...]

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21 January 2018

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30 October 2018

An interleukin-6 gene promoter polymorphism influences the biological phenotype of ovarian cancer

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical significance of interleukin-6 (IL-6) in the spread of gastric cancer: role of IL-6 as a prognostic factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/24886605

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Augmented gp130-mediated cytokine signalling accompanies human gastric cancer progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/24886605

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1186/1471-2407-14-357

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Europe PubMed Central

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19 March 2020

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19 March 2020

PubMed publication ID

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Europe PubMed Central

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19 March 2020

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