A drastic superoxide-dependent oxidative stress is prerequisite for the down-regulation of IRP1: Insights from studies on SOD1-deficient mice and macrophages treated with paraquat. (Q33707880)

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English	A drastic superoxide-dependent oxidative stress is prerequisite for the down-regulation of IRP1: Insights from studies on SOD1-deficient mice and macrophages treated with paraquat.	scientific article

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21 March 2020

A drastic superoxide-dependent oxidative stress is prerequisite for the down-regulation of IRP1: Insights from studies on SOD1-deficient mice and macrophages treated with paraquat (English)

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21 March 2020

Agnieszka Grzelak

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21 March 2020

Paweł Lipiński

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21 March 2020

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Anna Milczarek

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21 March 2020

Rafał R Starzyński

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21 March 2020

Agnieszka Styś

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21 March 2020

Aneta Jończy

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21 March 2020

Robert Staroń

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19 May 2017

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21 March 2020

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21 March 2020

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21 March 2020

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21 March 2020

e0176800

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21 March 2020

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19 May 2017

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Mice Overexpressing Both Non-Mutated Human SOD1 and Mutated SOD1(G93A) Genes: A Competent Experimental Model for Studying Iron Metabolism in Amyotrophic Lateral Sclerosis.

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The IRP1-HIF-2α axis coordinates iron and oxygen sensing with erythropoiesis and iron absorption

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Iron Regulatory Protein 1 Outcompetes Iron Regulatory Protein 2 in Regulating Cellular Iron Homeostasis in Response to Nitric Oxide

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Mechanism of cytotoxicity of paraquat

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Regulation of cellular iron metabolism

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Cytosolic and mitochondrial ferritins in the regulation of cellular iron homeostasis and oxidative damage

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SOD1 overexpression alters ROS production and reduces neurotoxic inflammatory signaling in microglial cells

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STAT5 proteins are involved in down-regulation of iron regulatory protein 1 gene expression by nitric oxide

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Absence of CuZn superoxide dismutase leads to elevated oxidative stress and acceleration of age-dependent skeletal muscle atrophy

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DNA and mRNA elements with complementary responses to hemin, antioxidant inducers, and iron control ferritin-L expression

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Cu/Zn superoxide dismutase and age-related hearing loss

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Cancer chemopreventive oltipraz generates superoxide anion radical

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CuZnSOD deficiency leads to persistent and widespread oxidative damage and hepatocarcinogenesis later in life

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Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress

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14 July 2018

Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis

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Compartment-specific protection of iron-sulfur proteins by superoxide dismutase

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14 July 2018

Iron regulatory proteins as NO signal transducers

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Nrf2 mediates the induction of ferritin H in response to xenobiotics and cancer chemopreventive dithiolethiones

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Recycling of RNA binding iron regulatory protein 1 into an aconitase after nitric oxide removal depends on mitochondrial ATP.

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14 July 2018

Regulation of ferritin genes and protein

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Free radicals in the physiological control of cell function

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Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice

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Yeast lacking superoxide dismutase(s) show elevated levels of "free iron" as measured by whole cell electron paramagnetic resonance

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14 July 2018

Down-regulation of iron regulatory protein 1 gene expression by nitric oxide

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14 July 2018

Superoxide and iron: partners in crime

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14 July 2018

Ovarian function in superoxide dismutase 1 and 2 knockout mice

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14 July 2018

Redox Modulation of Iron Regulatory Proteins by Peroxynitrite

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14 July 2018

Superoxide-driven aconitase FE-S center cycling

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14 July 2018

Aconitases: a class of metalloproteins highly sensitive to nitric oxide synthesis

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14 July 2018

Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury

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Modulation of iron regulatory protein functions. Further insights into the role of nitrogen- and oxygen-derived reactive species

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The bifunctional iron-responsive element binding protein/cytosolic aconitase: the role of active-site residues in ligand binding and regulation

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Evidence that the pathway of transferrin receptor mRNA degradation involves an endonucleolytic cleavage within the 3' UTR and does not involve poly(A) tail shortening.

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Oxidative stress induces activation of a cytosolic protein responsible for control of iron uptake.

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Rapid responses to oxidative stress mediated by iron regulatory protein.

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IRP1 regulates erythropoiesis and systemic iron homeostasis by controlling HIF2α mRNA translation

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Effect of overexpression of wild-type and mutant Cu/Zn-superoxide dismutases on oxidative stress and cell death induced by hydrogen peroxide, 4-hydroxynonenal or serum deprivation: potentiation of injury by ALS-related mutant superoxide dismutases a

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21 January 2018

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IRP1 activation by extracellular oxidative stress in the perfused rat liver

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21 January 2018

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10.1371/JOURNAL.PONE.0176800

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21 March 2020

2017PLoSO..1276800M

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21 March 2020

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21 March 2020

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