Secretion of sparfloxacin from the human intestinal Caco-2 cell line is altered by P-glycoprotein inhibitors. (Q33699230)

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5 December 2019

title

Secretion of sparfloxacin from the human intestinal Caco-2 cell line is altered by P-glycoprotein inhibitors (English)

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5 December 2019

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E Cormet-Boyaka

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5 December 2019

J F Huneau

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5 December 2019

A Mordrelle

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5 December 2019

P N Boyaka

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5 December 2019

C Carbon

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5 December 2019

E Rubinstein

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5 December 2019

D Tomé

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5 December 2019

language of work or name

English

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publication date

1 October 1998

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Antimicrobial Agents and Chemotherapy

5 December 2019

published in

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volume

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issue

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5 December 2019

page(s)

2607-2611

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Fluoroquinolone (ciprofloxacin) secretion by human intestinal epithelial (Caco‐2) cells

5 December 2019

cites work

1 reference

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Evidence for a passive diffusion mechanism for sparfloxacin uptake at the brush-border membrane of the human intestinal cell-line Caco-2.

21 June 2018

1 reference

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Intestinal elimination of ofloxacin enantiomers in the rat: evidence of a carrier-mediated process

21 June 2018

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Carrier-mediated intestinal transport of drugs

21 June 2018

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Active secretion of the fluoroquinolone ciprofloxacin by human intestinal epithelial Caco-2 cell layers

21 June 2018

1 reference

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Pharmacokinetics of gyrase inhibitors, Part 1: Basic chemistry and gastrointestinal disposition.

21 June 2018

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Active intestinal secretion of the fluoroquinolone antibacterials ciprofloxacin, norfloxacin and pefloxacin; a common secretory pathway?

21 June 2018

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Functional expression of P-glycoprotein in apical membranes of human intestinal Caco-2 cells. Kinetics of vinblastine secretion and interaction with modulators

21 June 2018

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Drug absorption limited by P-glycoprotein-mediated secretory drug transport in human intestinal epithelial Caco-2 cell layers

21 June 2018

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Effect of aerobic and anaerobic environments on antistaphylococcal activities of five fluoroquinolones

21 June 2018

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Intestinal elimination of sparfloxacin, fleroxacin, and ciprofloxacin in rats

21 June 2018

1 reference

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Measurement of protein using bicinchoninic acid

21 June 2018

1 reference

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Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability

21 June 2018

1 reference

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Pharmacokinetics of a novel quinolone, AT-4140, in animals

21 June 2018

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Pharmacology of drugs that alter multidrug resistance in cancer

21 June 2018

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Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues

21 June 2018

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Disposition and metabolism of [14C]sparfloxacin in the rat.

21 June 2018

1 reference

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The multidrug resistance and cystic fibrosis genes have complementary patterns of epithelial expression

21 June 2018

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Transport of celiprolol across human intestinal epithelial (Caco-2) cells: mediation of secretion by multiple transporters including P-glycoprotein

21 June 2018

1 reference

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Cytotoxic effects and metabolism of benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene in duodenal and ileal epithelial cell cultures

30 October 2018

1 reference

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Gastrointestinal secretion of ciprofloxacin. Evaluation of the charcoal model for investigations in healthy volunteers

30 October 2018

1 reference

12 December 2020

Transintestinal elimination of ciprofloxacin

1 reference

12 December 2020

The intestinal elimination of ciprofloxacin in the rat

1 reference

12 December 2020

Pharmacokinetics of sparfloxacin in humans after single oral administration at doses of 200, 400, 600, and 800 mg

1 reference

12 December 2020

Identifiers

DOI

10.1128/AAC.42.10.2607

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9756763%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

1 reference

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5 December 2019

PubMed publication ID

9756763

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9756763%20AND%20SRC:MED&resulttype=core&format=json