Can't get no SMADisfaction: Smad proteins as positive and negative regulators of TGF-beta family signals (Q33665042)

28 July 2017

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title

Can't get no SMADisfaction: Smad proteins as positive and negative regulators of TGF-beta family signals (English)

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28 July 2017

Christian JL

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28 July 2017

Nakayama T

series ordinal

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28 July 2017

language of work or name

English

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publication date

1 May 1999

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28 July 2017

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28 July 2017

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28 July 2017

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28 July 2017

page(s)

382-390

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TGF-beta signalling from cell membrane to nucleus through SMAD proteins

28 July 2017

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Mads and Smads in TGF beta signalling

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SMADs: mediators and regulators of TGF-beta signaling

21 January 2018

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TGF-beta signaling, Smads, and tumor suppressors

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Smads and early developmental signaling by the TGFbeta superfamily

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The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase

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MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

21 January 2018

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Receptor-associated Mad homologues synergize as effectors of the TGF-beta response

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TbetaRI phosphorylation of Smad2 on Ser465 and Ser467 is required for Smad2-Smad4 complex formation and signaling

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Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-beta signaling

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Transforming growth factor beta-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Targeted deletion of Smad4 shows it is required for transforming growth factor beta and activin signaling in colorectal cancer cells

21 January 2018

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21 January 2018

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21 January 2018

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Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic

21 January 2018

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Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

21 January 2018

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21 January 2018

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21 January 2018

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A transcriptional partner for MAD proteins in TGF-beta signalling

21 January 2018

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21 January 2018

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21 January 2018

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A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway

21 January 2018

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21 January 2018

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Heteromeric and homomeric interactions correlate with signaling activity and functional cooperativity of Smad3 and Smad4/DPC4

21 January 2018

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Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4

21 January 2018

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Vascular MAD s: Two novel MAD -related genes selectively inducible by flow in human vascular endothelium

21 January 2018

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Daughters against dpp modulates dpp organizing activity in Drosophila wing development

21 January 2018

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Smad6 inhibits signalling by the TGF-beta superfamily

21 January 2018

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Smad6 functions as an intracellular antagonist of some TGF-beta family members during Xenopus embryogenesis.

21 January 2018

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Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor

21 January 2018

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Physical and functional interaction of murine and Xenopus Smad7 with bone morphogenetic protein receptors and transforming growth factor-beta receptors

21 January 2018

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Interplay of signal mediators of decapentaplegic (Dpp): molecular characterization of mothers against dpp, Medea, and daughters against dpp.

21 January 2018

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Smad7 inhibits mesoderm formation and promotes neural cell fate in Xenopus embryos

21 January 2018

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Xenopus Smad7 inhibits both the activin and BMP pathways and acts as a neural inducer

21 January 2018

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21 January 2018

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Induction of Smad6 mRNA by bone morphogenetic proteins

21 January 2018

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21 January 2018

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21 January 2018

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Role of TAK1 and TAB1 in BMP signaling in early Xenopus development

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21 January 2018

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Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1

21 January 2018

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Smad proteins physically interact with calmodulin

21 January 2018

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10.1002/(SICI)1521-1878(199905)21:5<382::AID-BIES5>3.0.CO;2-V

21 January 2018

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DOI

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28 July 2017

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