Elimination of murine and human T-cell epitopes in recombinant immunotoxin eliminates neutralizing and anti-drug antibodies in vivo (Q33652098)

28 July 2017

title

Elimination of murine and human T-cell epitopes in recombinant immunotoxin eliminates neutralizing and anti-drug antibodies in vivo (English)

1 reference

28 July 2017

Devorah Crown

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28 July 2017

Gilad Kaplan

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28 July 2017

Ira Pastan

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28 July 2017

Ronit Mazor

1 reference

28 July 2017

Selamawit Addissie

series ordinal

1 reference

28 July 2017

Youjin Jang

series ordinal

1 reference

28 July 2017

publication date

19 October 2015

1 reference

Cellular and Molecular Immunology

28 July 2017

published in

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28 July 2017

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28 July 2017

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28 July 2017

page(s)

432-442

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Recombinant Immunotoxin with T-cell Epitope Mutations That Greatly Reduce Immunogenicity for Treatment of Mesothelin-Expressing Tumors

28 July 2017

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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Phase I trial of continuous infusion anti-mesothelin recombinant immunotoxin SS1P.

14 July 2018

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Engineering and biological characterization of VB6-845, an anti-EpCAM immunotoxin containing a T-cell epitope-depleted variant of the plant toxin bouganin

14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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Recombinant immunotoxins in the treatment of cancer

14 July 2018

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14 July 2018

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14 July 2018

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Crossref

https://api.crossref.org/works/10.1038%2FCMI.2015.91

Elimination of an immunodominant CD4+ T cell epitope in human IFN-beta does not result in an in vivo response directed at the subdominant epitope

21 January 2018

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https://api.crossref.org/works/10.1038%2FCMI.2015.91

Characterization of the B cell epitopes associated with a truncated form of Pseudomonas exotoxin (PE38) used to make immunotoxins for the treatment of cancer patients

21 January 2018

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12 December 2020

Phase 1 study of the antimesothelin immunotoxin SS1P in combination with pemetrexed and cisplatin for front-line therapy of pleural mesothelioma and correlation of tumor response with serum mesothelin, megakaryocyte potentiating factor, and cancer a

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12 December 2020

Hybrid transgenic immune tolerant mouse model for assessing the breaking of B cell tolerance by human interferon beta

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12 December 2020

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12 December 2020

Phase I study of SS1P, a recombinant anti-mesothelin immunotoxin given as a bolus I.V. infusion to patients with mesothelin-expressing mesothelioma, ovarian, and pancreatic cancers

1 reference

12 December 2020

Identifiers

DOI

10.1038/CMI.2015.91

1 reference

Dimensions Publication ID

28 July 2017

0 references

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28 July 2017

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