Duplication, multiduplication, and amplification of genes encoding drug-metabolizing enzymes: evolutionary, toxicological, and clinical pharmacological aspects (Q33639772)

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English	Duplication, multiduplication, and amplification of genes encoding drug-metabolizing enzymes: evolutionary, toxicological, and clinical pharmacological aspects	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

1 reference

Europe PubMed Central

Duplication, multiduplication, and amplification of genes encoding drug-metabolizing enzymes: evolutionary, toxicological, and clinical pharmacological aspects (English)

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

author name string

Ingelman-Sundberg M

1

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

language of work or name

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publication date

1 May 1999

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Drug Metabolism Reviews

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Europe PubMed Central

PubMed publication ID

28 July 2017

31

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Europe PubMed Central

PubMed publication ID

28 July 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

449-459

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Europe PubMed Central

PubMed publication ID

28 July 2017

Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101930

21 January 2018

Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101930

21 January 2018

Distinct phenotypes and genotypes of debrisoquine hydroxylation among Europeans and Chinese

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101930

21 January 2018

Evolution of a highly polymorphic human cytochrome P450 gene cluster: CYP2D6.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101930

21 January 2018

Genetic polymorphism of CYP2D6 and lung cancer risk in African-Americans and Caucasians in Los Angeles County

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101930

21 January 2018

Frequent occurrence of CYP2D6 gene duplication in Saudi Arabians

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101930

21 January 2018

Molecular heterogeneity at the CYP2D gene locus in Nicaraguans: impact of gene-flow from Europe

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101930

21 January 2018

Molecular basis for rational megaprescribing in ultrarapid hydroxylators of debrisoquine

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101930

21 January 2018

Disassociation between debrisoquine hydroxylation phenotype and genotype among Chinese

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101930

21 January 2018

Prevalence of CYP2D6 gene duplication and its repercussion on the oxidative phenotype in a white population

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101930

21 January 2018

Genetic polymorphism of cytochrome P450 CYP2D6 in Zimbabwean population

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101930

21 January 2018

Xenobiotic and endobiotic inhibitors of cytochrome P-450dbl function, the target of the debrisoquine/sparteine type polymorphism

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101930

21 January 2018

Ultrarapid metabolizers of debrisoquine: Characterization and PCR-based detection of alleles with duplication of the CYP2D6 gene

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101930

21 January 2018

10-Hydroxylation of nortriptyline in white persons with 0, 1, 2, 3, and 13 functional CYP2D6 genes

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101930

21 January 2018

Genetically deficient CYP2D6 metabolism provides protection against oral opiate dependence.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101930

21 January 2018

Identifiers

10.1081/DMR-100101930

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

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