Azides derived from colchicine and their use in library synthesis: A practical entry to new bioactive derivatives of an old natural drug. (Q33540746)

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19 January 2020

title

Azides derived from colchicine and their use in library synthesis: A practical entry to new bioactive derivatives of an old natural drug (English)

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19 January 2020

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19 January 2020

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19 January 2020

Norman Nicolaus

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19 January 2020

Janet Zapke

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19 January 2020

Philipp Riesterer

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19 January 2020

Jörg-Martin Neudörfl

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19 January 2020

Aram Prokop

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19 January 2020

publication date

1 May 2010

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19 January 2020

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19 January 2020

volume

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issue

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19 January 2020

page(s)

661-665

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Current perspectives on familial Mediterranean fever

19 January 2020

cites work

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Update on colchicine and its mechanism of action

21 January 2018

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Variations in the colchicine-binding domain provide insight into the structural switch of tubulin

21 January 2018

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21 January 2018

Colchicine update: 2008.

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Total syntheses of colchicine in comparison: a journey through 50 years of synthetic organic chemistry.

21 January 2018

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Asymmetric synthesis of antimicrotubule biaryl hybrids of allocolchicine and steganacin.

21 January 2018

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Microtubules as a target for anticancer drugs

21 January 2018

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Disrupting tumour blood vessels

21 January 2018

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In silico design of tubulin-targeted antimitotic peptides

21 January 2018

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Anti-mitotic activity of colchicine and the structural basis for its interaction with tubulin

21 January 2018

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Synthesis and characterization of a cobalamin-colchicine conjugate as a novel tumor-targeted cytotoxin.

21 January 2018

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Inhibition of mitosis by glycopeptide dendrimer conjugates of colchicine

21 January 2018

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Colchitaxel, a coupled compound made from microtubule inhibitors colchicine and paclitaxel

21 January 2018

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Colchicine glycorandomization influences cytotoxicity and mechanism of action

21 January 2018

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A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes

21 January 2018

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The growing impact of click chemistry on drug discovery

21 January 2018

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Cu-catalyzed azide-alkyne cycloaddition

21 January 2018

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The chemistry of amine-azide interconversion: catalytic diazotransfer and regioselective azide reduction

21 January 2018

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Controlled microwave heating in modern organic synthesis.

21 January 2018

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A [2 + 2 + 2]-cycloaddition approach toward 6-oxa-allocolchicinoids with apoptosis-inducing activity

21 January 2018

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R-253 disrupts microtubule networks in multiple tumor cell lines

21 January 2018

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Immunofluorescence localization of HeLa cell microtubule-associated proteins on microtubules in vitro and in vivo

21 January 2018

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HeLa cells 50 years on: the good, the bad and the ugly

21 January 2018

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Natural product hybrids as new leads for drug discovery

21 January 2018

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1.3-Dipolare Cycloadditionen Rückschau und Ausblick

21 January 2018

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Colchicine analogs in the treatment of acute gout

21 January 2018

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7 January 2021

Biological effects of modified colchicines. 2. Evaluation of catecholic colchicines, colchifolines, colchicide, and novel N-acyl- and N-aroyldeacetylcolchicines

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7 January 2021

Facile construction of the colchicine skeleton by a rhodium-catalyzed cyclization/cycloaddition cascade

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7 January 2021

Total synthesis of (-)-colchicine via a Rh-triggered cycloaddition cascade

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7 January 2021

Variation and Selection

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7 January 2021

Metal catalyzed diazo transfer for the synthesis of azides from amines

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000063

7 January 2021

One-pot procedure for diazo transfer and azide-alkyne cycloaddition: triazole linkages from amines

1 reference

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7 January 2021

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7 January 2021

Piceatannol, a hydroxylated analog of the chemopreventive agent resveratrol, is a potent inducer of apoptosis in the lymphoma cell line BJAB and in primary, leukemic lymphoblasts

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7 January 2021

Identifiers

DOI

10.1002/CMDC.201000063

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20229567%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

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