A naturally occurring mutation in ropB suppresses SpeB expression and reduces M1T1 group A streptococcal systemic virulence (Q33396665)

26 July 2017

title

A naturally occurring mutation in ropB suppresses SpeB expression and reduces M1T1 group A streptococcal systemic virulence (English)

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26 July 2017

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26 July 2017

Victor Nizet

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Mark J Walker

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Malak Kotb

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26 July 2017

Andrew Hollands

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26 July 2017

Rita Kansal

series ordinal

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26 July 2017

language of work or name

English

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publication date

31 December 2008

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26 July 2017

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26 July 2017

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26 July 2017

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26 July 2017

page(s)

e4102

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Creative Commons Attribution 4.0 International

26 July 2017

start time

31 December 2008

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April 2022 Public Data File from Crossref

copyrighted

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cites work

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Rgg regulates growth phase-dependent expression of proteins associated with secondary metabolism and stress in Streptococcus pyogenes

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SpeB modulates fibronectin-dependent internalization of Streptococcus pyogenes by efficient proteolysis of cell-wall-anchored protein F1.

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Invasive M1T1 group A Streptococcus undergoes a phase-shift in vivo to prevent proteolytic degradation of multiple virulence factors by SpeB.

21 June 2018

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Rgg Coordinates Virulence Factor Synthesis and Metabolism inStreptococcus pyogenes

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Role of RopB in growth phase expression of the SpeB cysteine protease of Streptococcus pyogenes

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Trigger factor-mediated prolyl isomerization influences maturation of the Streptococcus pyogenes cysteine protease

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Molecular genetic analysis of a group A Streptococcus operon encoding serum opacity factor and a novel fibronectin-binding protein, SfbX

21 June 2018

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Rgg influences the expression of multiple regulatory loci to coregulate virulence factor expression in Streptococcus pyogenes

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21 June 2018

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Group A streptococcal rofA gene is involved in the control of several virulence genes and eukaryotic cell attachment and internalization

21 June 2018

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Inverse relation between disease severity and expression of the streptococcal cysteine protease, SpeB, among clonal M1T1 isolates recovered from invasive group A streptococcal infection cases

21 June 2018

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21 June 2018

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21 June 2018

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The rgg gene of Streptococcus pyogenes NZ131 positively influences extracellular SPE B production.

21 June 2018

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Molecular analysis of the role of the group A streptococcal cysteine protease, hyaluronic acid capsule, and M protein in a murine model of human invasive soft-tissue infection

21 June 2018

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Genetic inactivation of an extracellular cysteine protease (SpeB) expressed by Streptococcus pyogenes decreases resistance to phagocytosis and dissemination to organs

21 June 2018

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Substitution of cysteine 192 in a highly conserved Streptococcus pyogenes extracellular cysteine protease (interleukin 1beta convertase) alters proteolytic activity and ablates zymogen processing.

21 June 2018

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Clonal basis for resurgence of serious Streptococcus pyogenes disease in the 1980s

21 June 2018

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DNase Sda1 provides selection pressure for a switch to invasive group A streptococcal infection

21 June 2018

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Post-proteomic identification of a novel phage-encoded streptodornase, Sda1, in invasive M1T1 Streptococcus pyogenes

31 October 2018

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Mouse skin passage of Streptococcus pyogenes results in increased streptokinase expression and activity

31 October 2018

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Selective modulation of superantigen-induced responses by streptococcal cysteine protease

31 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605554

Role for a secreted cysteine proteinase in the establishment of host tissue tropism by group A streptococci.

31 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605554

A role for the fibrinogen-binding regions of streptococcal M proteins in phagocytosis resistance.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605554

A secreted streptococcal cysteine protease can cleave a surface-expressed M1 protein and alter the immunoglobulin binding properties

31 October 2018

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12 December 2020

Generation of a mature streptococcal cysteine proteinase is dependent on cell wall-anchored M1 protein

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12 December 2020

Trigger for group A streptococcal M1T1 invasive disease

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12 December 2020

The resurgence of group A streptococcal infections and their sequelae

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12 December 2020

Severe Invasive Group A Streptococcal Infections In Ontario, Canada: 1987-1991

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12 December 2020

Allelic variants of streptokinase from Streptococcus pyogenes display functional differences in plasminogen activation

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12 December 2020

10.1371/JOURNAL.PONE.0004102

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DOI

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26 July 2017

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26 July 2017

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