Lessons from Nature: microRNA-based shRNA libraries (Q33255058)

24 July 2017

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title

Lessons from Nature: microRNA-based shRNA libraries (English)

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24 July 2017

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Gregory J Hannon

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24 July 2017

Kenneth Chang

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24 July 2017

Stephen J Elledge

series ordinal

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24 July 2017

publication date

1 September 2006

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24 July 2017

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24 July 2017

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24 July 2017

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24 July 2017

page(s)

707-714

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RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals

24 July 2017

cites work

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A species of small antisense RNA in posttranscriptional gene silencing in plants

21 January 2018

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An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

21 January 2018

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Role for a bidentate ribonuclease in the initiation step of RNA interference

21 January 2018

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Argonaute2, a link between genetic and biochemical analyses of RNAi

21 January 2018

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Targeted mRNA degradation by double-stranded RNA in vitro

21 January 2018

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Argonaute2 is the catalytic engine of mammalian RNAi

21 January 2018

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Crystal structure of Argonaute and its implications for RISC slicer activity

21 January 2018

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Asymmetry in the assembly of the RNAi enzyme complex

21 January 2018

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Functional siRNAs and miRNAs Exhibit Strand Bias

21 January 2018

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The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

21 January 2018

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Negative regulatory sequences in the lin-14 3'-untranslated region are necessary to generate a temporal switch during Caenorhabditis elegans development

21 January 2018

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MicroRNAs: genomics, biogenesis, mechanism, and function

21 January 2018

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MicroRNAs: small RNAs with a big role in gene regulation

21 January 2018

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MicroRNA genes are transcribed by RNA polymerase II

21 January 2018

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Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs

21 January 2018

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The nuclear RNase III Drosha initiates microRNA processing

21 January 2018

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Processing of primary microRNAs by the Microprocessor complex

21 January 2018

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The human DiGeorge syndrome critical region gene 8 and Its D. melanogaster homolog are required for miRNA biogenesis

21 January 2018

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The Drosha-DGCR8 complex in primary microRNA processing

21 January 2018

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The Microprocessor complex mediates the genesis of microRNAs

21 January 2018

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Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex

21 January 2018

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Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs

21 January 2018

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Nuclear export of microRNA precursors

21 January 2018

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Synthetic shRNAs as potent RNAi triggers

21 January 2018

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The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes

21 January 2018

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Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

21 January 2018

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A resource for large-scale RNA-interference-based screens in mammals.

21 January 2018

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Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells

21 January 2018

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A genetic screen for candidate tumor suppressors identifies REST

21 January 2018

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Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy

21 January 2018

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MicroRNAs modulate hematopoietic lineage differentiation

21 January 2018

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Sequence requirements for micro RNA processing and function in human cells

21 January 2018

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Structural elements of ornithine decarboxylase required for intracellular degradation and polyamine-dependent regulation

21 January 2018

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A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells

21 January 2018

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Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach

21 January 2018

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Second-generation shRNA libraries covering the mouse and human genomes

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Probing tumor phenotypes using stable and regulated synthetic microRNA precursors

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

MAGIC, an in vivo genetic method for the rapid construction of recombinant DNA molecules

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NMETH923

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Dimensions Publication ID

24 July 2017

1043372050

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