Cytochrome P450 enzymes in the generation of commercial products (Q31096798)

28 June 2017

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title

Cytochrome P450 enzymes in the generation of commercial products (English)

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28 June 2017

F Peter Guengerich

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28 June 2017

publication date

1 May 2002

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Nature Reviews Drug Discovery

28 June 2017

published in

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28 June 2017

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28 June 2017

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28 June 2017

page(s)

359-366

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Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity

28 June 2017

cites work

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Genetically modified plants and human health risks: Can additional research reduce uncertainties and increase public confidence?

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Alteration of mouse cytochrome P450coh substrate specificity by mutation of a single amino-acid residue

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Microbial hydroxylation of ML-236B (compactin) and monacolin K (MB-530B)

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Substrate specificity of 6-deoxyerythronolide B hydroxylase, a bacterial cytochrome P450 of erythromycin A biosynthesis

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Aromatase inhibitors in the treatment of breast cancer

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Directed evolution of the fatty-acid hydroxylase P450 BM-3 into an indole-hydroxylating catalyst

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The great diversity of reactions catalyzed by cytochromes P450

21 January 2018

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Engineering cytochrome P-450cam to increase the stereospecificity and coupling of aliphatic hydroxylation

21 January 2018

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The use of random chimeragenesis to study structure/function properties of rat and human P450c17

21 January 2018

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Cytochrome P450 1B1: a target for inhibition in anticarcinogenesis strategies

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Destruction of heme and hemoproteins mediated by liver microsomal reduced nicotinamide adenine dinucleotide phosphate-cytochrome P-450 reductase

31 March 2020

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Butane and propane oxidation by engineered cytochrome P450cam.

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRD792

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Dimensions Publication ID

28 June 2017

1006979163

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