Mechanosensory hair cells express two molecularly distinct mechanotransduction channels (Q30833261)

18 October 2017

Mechanosensory hair cells express two molecularly distinct mechanotransduction channels (English)

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18 October 2017

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6 June 2020

Christopher L Cunningham

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6 June 2020

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6 June 2020

Ardem Patapoutian

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6 June 2020

Robert Fettiplace

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6 June 2020

Bertrand Coste

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6 June 2020

Ulrich Mueller

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6 June 2020

Sarah Harkins-Perry

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6 June 2020

Sanjeev Ranade

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6 June 2020

Zizhen Wu

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6 June 2020

Nicolas Grillet

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6 June 2020

Navid Zebarjadi

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6 June 2020

language of work or name

English

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publication date

28 November 2016

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18 October 2017

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6 June 2020

volume

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6 June 2020

issue

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6 June 2020

page(s)

24-33

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Development and localization of reverse-polarity mechanotransducer channels in cochlear hair cells

6 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Piezo2 is the principal mechanotransduction channel for proprioception.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

The Piezo Mechanosensitive Ion Channels: May the Force Be with You!

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

The effects of Tmc1 Beethoven mutation on mechanotransducer channel function in cochlear hair cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

TMC1 and TMC2 Localize at the Site of Mechanotransduction in Mammalian Inner Ear Hair Cell Stereocilia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Piezo1 links mechanical forces to red blood cell volume

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Subunit determination of the conductance of hair-cell mechanotransducer channels

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

TMIE is an essential component of the mechanotransduction machinery of cochlear hair cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Conductance and block of hair-cell mechanotransducer channels in transmembrane channel-like protein mutants

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Piezo1, a mechanically activated ion channel, is required for vascular development in mice.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Transduction without tip links in cochlear hair cells is mediated by ion channels with permeation properties distinct from those of the mechano-electrical transducer channel.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Piezo2 is required for Merkel-cell mechanotransduction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

The role of transmembrane channel-like proteins in the operation of hair cell mechanotransducer channels

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

TMC1 and TMC2 are components of the mechanotransduction channel in hair cells of the mammalian inner ear

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

A prestin motor in chicken auditory hair cells: active force generation in a nonmammalian species

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Active cochlear amplification is dependent on supporting cell gap junctions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

A role for Piezo2 in EPAC1-dependent mechanical allodynia.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Developmental changes in the cochlear hair cell mechanotransducer channel and their regulation by transmembrane channel-like proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

TMHS is an integral component of the mechanotransduction machinery of cochlear hair cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Inflammatory signals enhance piezo2-mediated mechanosensitive currents

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Kinocilia mediate mechanosensitivity in developing zebrafish hair cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Piezo proteins are pore-forming subunits of mechanically activated channels

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Mechanotransduction in mouse inner ear hair cells requires transmembrane channel-like genes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Mutations in Protocadherin 15 and Cadherin 23 Affect Tip Links and Mechanotransduction in Mammalian Sensory Hair Cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Topology of Transmembrane Channel-like Gene 1 Protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Calcium balance and mechanotransduction in rat cochlear hair cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Mechanotransduction by hair cells: models, molecules, and mechanisms

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Mutations in LOXHD1, an evolutionarily conserved stereociliary protein, disrupt hair cell function in mice and cause progressive hearing loss in humans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Harmonin mutations cause mechanotransduction defects in cochlear hair cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Tonotopic gradient in the developmental acquisition of sensory transduction in outer hair cells of the mouse cochlea

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Localization of inner hair cell mechanotransducer channels using high-speed calcium imaging.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Cochlear outer hair cell motility

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Stepwise morphological and functional maturation of mechanotransduction in rat outer hair cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

A forward genetics screen in mice identifies recessive deafness traits and reveals that pejvakin is essential for outer hair cell function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Differential expression of otoferlin in brain, vestibular system, immature and mature cochlea of the rat

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Active hair bundle movements in auditory hair cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

The concentrations of calcium buffering proteins in mammalian cochlear hair cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Competence, specification and commitment in otic placode induction.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Expression of Pax2 and patterning of the chick inner ear.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

A mutation in OTOF, encoding otoferlin, a FER-1-like protein, causes DFNB9, a nonsyndromic form of deafness

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Detection of Ca2+ entry through mechanosensitive channels localizes the site of mechanoelectrical transduction in hair cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Kinetics of the receptor current in bullfrog saccular hair cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Forward and reverse transduction in the mammalian cochlea

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Tip-link integrity and mechanical transduction in vertebrate hair cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Stretch sensitivity of the lateral wall of the auditory outer hair cell from the guinea pig.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Stretch-activated ion channels in guinea pig outer hair cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5191906

Generation of Pax2-Cre mice by modification of a Pax2 bacterial artificial chromosome

21 June 2018

1 reference

Pax-2 expression in the murine neural plate precedes and encompasses the expression domains of Wnt-1 and En-1

21 January 2018

1 reference

A hearing and vestibular phenotyping pipeline to identify mouse mutants with hearing impairment

21 January 2018

1 reference

Cl- flux through a non-selective, stretch-sensitive conductance influences the outer hair cell motor of the guinea-pig

21 January 2018

1 reference

Spatially and temporally restricted expression of Pax2 during murine neurogenesis

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27893727

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Reversible inhibition of voltage-dependent outer hair cell motility and capacitance

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27893727

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NN.4449

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27893727%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27893727%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

PubMed publication ID

27893727

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27893727%20AND%20SRC:MED&resulttype=core&format=json