Pharmacologically Improved Contractility Protects Against Aortic Dissection in Mice With Disrupted Transforming Growth Factor-β Signaling Despite Compromised Extracellular Matrix Properties (Q30749956)

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English	Pharmacologically Improved Contractility Protects Against Aortic Dissection in Mice With Disrupted Transforming Growth Factor-β Signaling Despite Compromised Extracellular Matrix Properties	scientific article

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scholarly article

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Europe PubMed Central

PMC publication ID

16 August 2017

Pharmacologically Improved Contractility Protects Against Aortic Dissection in Mice With Disrupted Transforming Growth Factor-β Signaling Despite Compromised Extracellular Matrix Properties (English)

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Europe PubMed Central

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16 August 2017

extracellular matrix

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1 reference

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inferred from title

Magdalene Y L Ting

6

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26988590%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

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Jacopo Ferruzzi

1

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1 June 2020

Sae-Il Murtada

2

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1 June 2020

Guangxin Li

3

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1 June 2020

Yang Jiao

4

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1 June 2020

Selen Uman

5

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1 June 2020

George Tellides

7

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1 June 2020

Jay D Humphrey

8

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1 June 2020

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publication date

17 March 2016

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16 August 2017

Arteriosclerosis, Thrombosis, and Vascular Biology

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26988590%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

36

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1 June 2020

5

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1 June 2020

919-927

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26988590%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Reduced Biaxial Contractility in the Descending Thoracic Aorta of Fibulin-5 Deficient Mice

1 reference

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20 June 2018

A deleterious gene-by-environment interaction imposed by calcium channel blockers in Marfan syndrome.

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20 June 2018

Role of mechanotransduction in vascular biology: focus on thoracic aortic aneurysms and dissections

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The structural factor of hypertension: large and small artery alterations

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Decreased elastic energy storage, not increased material stiffness, characterizes central artery dysfunction in fibulin-5 deficiency independent of sex

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20 June 2018

Myh11(R247C/R247C) mutations increase thoracic aorta vulnerability to intramural damage despite a general biomechanical adaptivity

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Mechano-biology in the thoracic aortic aneurysm: a review and case study

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Tgfbr2 disruption in postnatal smooth muscle impairs aortic wall homeostasis

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Inflammation and mechanical stretch promote aortic stiffening in hypertension through activation of p38 mitogen-activated protein kinase.

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Recurrent gain-of-function mutation in PRKG1 causes thoracic aortic aneurysms and acute aortic dissections

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Angiotensin-converting enzyme-induced activation of local angiotensin signaling is required for ascending aortic aneurysms in fibulin-4-deficient mice.

1 reference

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20 June 2018

Possible mechanical roles of glycosaminoglycans in thoracic aortic dissection and associations with dysregulated transforming growth factor-β.

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Matrix-dependent perturbation of TGFβ signaling and disease

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Lessons on the pathogenesis of aneurysm from heritable conditions

1 reference

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Mutations in myosin light chain kinase cause familial aortic dissections

1 reference

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TGFBR2 mutations alter smooth muscle cell phenotype and predispose to thoracic aortic aneurysms and dissections

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Thoracic aortic aneurysm clinically pertinent controversies and uncertainties

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20 June 2018

Cellular and molecular mechanisms of thoracic aortic aneurysms

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Fundamental role of axial stress in compensatory adaptations by arteries

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20 June 2018

Regional heterogeneity within the aorta: relevance to aneurysm disease

1 reference

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20 June 2018

Genetic basis of thoracic aortic aneurysms and dissections: focus on smooth muscle cell contractile dysfunction

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20 June 2018

Mutations in smooth muscle alpha-actin (ACTA2) lead to thoracic aortic aneurysms and dissections.

1 reference

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20 June 2018

MYH11 mutations result in a distinct vascular pathology driven by insulin-like growth factor 1 and angiotensin II

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Mutations in myosin heavy chain 11 cause a syndrome associating thoracic aortic aneurysm/aortic dissection and patent ductus arteriosus

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12 December 2020

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10.1161/ATVBAHA.116.307436

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Europe PubMed Central

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1 June 2020

PMC publication ID

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Europe PubMed Central

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1 June 2020

PubMed publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26988590%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

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