Immunostimulatory Motifs Enhance Antiviral siRNAs Targeting Highly Pathogenic Avian Influenza H5N1 (Q30404683)

18 October 2017

Immunostimulatory Motifs Enhance Antiviral siRNAs Targeting Highly Pathogenic Avian Influenza H5N1 (English)

1 reference

10.1371/JOURNAL.PONE.0021552

DOI

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0021552

6 December 2024

1 reference

1 reference

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6 December 2024

Sue Lowther

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18 October 2017

Cameron R. Stewart

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21747939

6 December 2024

Adam J. Karpala

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21747939

6 December 2024

John W. Lowenthal

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21747939

6 December 2024

Andrew G. Bean

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6 December 2024

language of work or name

English

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publication date

1 July 2011

1 reference

18 October 2017

2011

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21747939

full work available at URL

6 December 2024

https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0021552&type=printable

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21747939

https://europepmc.org/articles/PMC3128588

6 December 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21747939

https://europepmc.org/articles/PMC3128588?pdf=render

6 December 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21747939

http://dx.plos.org/10.1371/journal.pone.0021552

6 December 2024

1 reference

10.1371/JOURNAL.PONE.0021552

DOI

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0021552

6 December 2024

1 reference

18 October 2017

1 reference

18 October 2017

1 reference

18 October 2017

e21552

1 reference

Creative Commons Attribution 4.0 International

18 October 2017

start time

1 July 2011

1 reference

April 2022 Public Data File from Crossref

copyrighted

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cites work

Association of RIG-I with innate immunity of ducks to influenza

1 reference

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Rational design of immunostimulatory siRNAs.

20 June 2018

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Pandemic influenza: an inconvenient mutation.

20 June 2018

1 reference

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The promises and pitfalls of RNA-interference-based therapeutics

20 June 2018

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Increased potency and longevity of gene silencing using validated Dicer substrates

20 June 2018

1 reference

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5'-Triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma

20 June 2018

1 reference

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Molecular cloning, expression, and characterization of chicken IFN -lambda

20 June 2018

1 reference

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Sequence- and target-independent angiogenesis suppression by siRNA via TLR3

20 June 2018

1 reference

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Activation of the TLR3 pathway regulates IFNbeta production in chickens

20 June 2018

1 reference

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Interfering with disease: a progress report on siRNA-based therapeutics

20 June 2018

1 reference

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Strategies for silencing human disease using RNA interference

20 June 2018

1 reference

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siRNA and isRNA: two edges of one sword

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128588

Inhibition of viruses by RNA interference

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128588

Induction of the interferon response by siRNA is cell type- and duplex length-dependent

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128588

Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128588

Determinants of interferon-stimulated gene induction by RNAi vectors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128588

Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128588

Activation of the interferon system by short-interfering RNAs

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128588

Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128588

RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128588

Arabidopsis SGS2 and SGS3 genes are required for posttranscriptional gene silencing and natural virus resistance

20 June 2018

1 reference

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Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo

20 June 2018

1 reference

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Vaccine sought as bird flu infects humans

20 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0021552

Synthetic double-stranded RNA oligonucleotides are immunostimulatory for chicken spleen cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0021552

Inhibition of toll-like receptor 7- and 9-mediated alpha/beta interferon production in human plasmacytoid dendritic cells by respiratory syncytial virus and measles virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0021552

Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0021552

Induction of an interferon response by RNAi vectors in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0021552

Characterization of chicken Mda5 activity: regulation of IFN-β in the absence of RIG-I functionality

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128588

Chicken flu races through Dutch poultry farms

26 November 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0021552

Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21747939

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0021552

1 reference

18 October 2017

0 references

1 reference

18 October 2017

1 reference