The Brassica-derived phytochemical indolo[3,2-b]carbazole protects against oxidative DNA damage by aryl hydrocarbon receptor activation (Q30315579)

17 June 2017

title

The Brassica-derived phytochemical indolo[3,2-b]carbazole protects against oxidative DNA damage by aryl hydrocarbon receptor activation (English)

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17 June 2017

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Teodora Nikolova

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17 June 2017

Dagmar Faust

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17 June 2017

Wim Wätjen

series ordinal

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17 June 2017

Bernd Kaina

series ordinal

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17 June 2017

Cornelia Dietrich

series ordinal

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17 June 2017

publication date

8 February 2016

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17 June 2017

published in

Archives of Toxicology

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17 June 2017

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17 June 2017

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17 June 2017

page(s)

967-982

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Inhibition of cigarette smoke-related DNA adducts in rat tissues by indole-3-carbinol.

17 June 2017

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21 January 2018

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Exactly the Same but Different: Promiscuity and Diversity in the Molecular Mechanisms of Action of the Aryl Hydrocarbon (Dioxin) Receptor

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Identification of ultimate DNA damaging oxygen species

21 January 2018

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Rat, but not human, sulfotransferase activates a tamoxifen metabolite to produce DNA adducts and gene mutations in bacteria and mammalian cells in culture

21 January 2018

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1-Methoxy-3-indolylmethyl glucosinolate; a potent genotoxicant in bacterial and mammalian cells: Mechanisms of bioactivation.

21 January 2018

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Dietary polyphenols increase paraoxonase 1 gene expression by an aryl hydrocarbon receptor-dependent mechanism

21 January 2018

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21 January 2018

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Aryl Hydrocarbon Receptor Activation Down-Regulates IL-7 and Reduces Inflammation in a Mouse Model of DSS-Induced Colitis

21 January 2018

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Genotoxic effects of crude juices from Brassica vegetables and juices and extracts from phytopharmaceutical preparations and spices of cruciferous plants origin in bacterial and mammalian cells.

21 January 2018

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Aryl hydrocarbon receptor suppresses intestinal carcinogenesis in ApcMin/+ mice with natural ligands

21 January 2018

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Novel compound 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazo-phenyl)-amide (CH-223191) prevents 2,3,7,8-TCDD-induced toxicity by antagonizing the aryl hydrocarbon receptor

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Extended treatment with physiologic concentrations of dietary phytochemicals results in altered gene expression, reduced growth, and apoptosis of cancer cells.

21 January 2018

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Role of aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxicity and cancer

21 January 2018

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The search for endogenous activators of the aryl hydrocarbon receptor

21 January 2018

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Homologous recombination protects mammalian cells from replication-associated DNA double-strand breaks arising in response to methyl methanesulfonate

21 January 2018

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The γH2AX assay for genotoxic and nongenotoxic agents: comparison of H2AX phosphorylation with cell death response

21 January 2018

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Regulation of Nrf2-an update

21 January 2018

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The transcriptional activation of the human copper/zinc superoxide dismutase gene by 2,3,7,8-tetrachlorodibenzo-p-dioxin through two different regulator sites, the antioxidant responsive element and xenobiotic responsive element

21 January 2018

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Induction of cytochrome P4501A1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin or indolo(3,2-b)carbazole is associated with oxidative DNA damage

21 January 2018

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Aryl hydrocarbon receptor facilitates DNA strand breaks and 8-oxo-2'-deoxyguanosine formation by the aldo-keto reductase product benzo[a]pyrene-7,8-dione

21 January 2018

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Comparison of acute toxicities of indolo[3,2-b]carbazole (ICZ) and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in TCDD-sensitive rats

21 January 2018

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The aryl hydrocarbon receptor cross-talks with multiple signal transduction pathways

21 January 2018

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Genotoxicity of naturally occurring indole compounds: correlation between covalent DNA binding and other genotoxicity tests

21 January 2018

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Brca2/Xrcc2 dependent HR, but not NHEJ, is required for protection against O(6)-methylguanine triggered apoptosis, DSBs and chromosomal aberrations by a process leading to SCEs

21 January 2018

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Effect of diet and route of administration on the DNA binding of aflatoxin B1 in the rat.

21 January 2018

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The aryl hydrocarbon receptor suppresses cigarette-smoke-induced oxidative stress in association with dioxin response element (DRE)-independent regulation of sulfiredoxin 1.

21 January 2018

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Nuclear factor-erythroid 2-related factor 2 as a chemopreventive target in colorectal cancer.

21 January 2018

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Glutathione redox state regulates mitochondrial reactive oxygen production

21 January 2018

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Regulatory effects of dioxin-like and non-dioxin-like PCBs and other AhR ligands on the antioxidant enzymes paraoxonase 1/2/3.

21 January 2018

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Cyp1a2 protects against reactive oxygen production in mouse liver microsomes

21 January 2018

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Measurement of protein using bicinchoninic acid

21 January 2018

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A novel induction mechanism of the rat CYP1A2 gene mediated by Ah receptor-Arnt heterodimer

21 January 2018

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Development of a multi-organ rat model for evaluating chemopreventive agents: efficacy of indole-3-carbinol

21 January 2018

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The aryl hydrocarbon receptor regulates mouse Fshr promoter activity through an e-box binding site.

21 January 2018

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Mutagenicity of TCDD in Big Blue transgenic rats

21 January 2018

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Does mechanistic understanding help in risk assessment--the example of dioxins

21 January 2018

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Caco-2 cell permeability assays to measure drug absorption.

21 January 2018

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A review of mechanisms underlying anticarcinogenicity by brassica vegetables

21 January 2018

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Prenylation enhances cytotoxicity of apigenin and liquiritigenin in rat H4IIE hepatoma and C6 glioma cells

21 January 2018

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TCDD induces c-jun expression via a novel Ah (dioxin) receptor-mediated p38-MAPK-dependent pathway.

21 January 2018

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High mutagenic activity of juice from pak choi (Brassica rapa ssp. chinensis) sprouts due to its content of 1-methoxy-3-indolylmethyl glucosinolate, and its enhancement by elicitation with methyl jasmonate.

21 January 2018

1 reference

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The tumor suppressor Kruppel-like factor 6 is a novel aryl hydrocarbon receptor DNA binding partner

21 January 2018

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Induction of hepatic 8-oxo-deoxyguanosine adducts by 2,3,7,8-tetrachlorodibenzo-p-dioxin in Sprague-Dawley rats is female-specific and estrogen-dependent

21 January 2018

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Chemoprevention of dietary digitoflavone on colitis-associated colon tumorigenesis through inducing Nrf2 signaling pathway and inhibition of inflammation

21 January 2018

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Dietary indole-3-carbinol promotes endometrial adenocarcinoma development in rats initiated with N-ethyl-N'-nitro-N-nitrosoguanidine, with induction of cytochrome P450s in the liver and consequent modulation of estrogen metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-016-1672-4

CH223191 is a ligand-selective antagonist of the Ah (Dioxin) receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-016-1672-4

3'-methoxy-4'-nitroflavone, a reported aryl hydrocarbon receptor antagonist, enhances Cyp1a1 transcription by a dioxin responsive element-dependent mechanism

21 January 2018

1 reference

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Indole-3-carbinol inhibits 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone plus benzo(a)pyrene-induced lung tumorigenesis in A/J mice and modulates carcinogen-induced alterations in protein levels

21 January 2018

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.1158/0008-5472.CAN-06-4438

Identifiers

DOI

10.1007/S00204-016-1672-4

1 reference

Dimensions Publication ID

17 June 2017

1000657172

0 references

1 reference