STRUCTURAL VIROLOGY. X-ray crystal structures of native HIV-1 capsid protein reveal conformational variability. (Q30279235)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26044298%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

title

STRUCTURAL VIROLOGY. X-ray crystal structures of native HIV-1 capsid protein reveal conformational variability (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26044298%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

main subject

crystal structure

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X-ray crystallography

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1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26044298%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26044298%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

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16 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26044298%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Vineet N KewalRamani

1 reference

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16 February 2020

Owen Pornillos

series ordinal

1 reference

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16 February 2020

language of work or name

English

0 references

publication date

4 June 2015

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16 February 2020

1 reference

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16 February 2020

volume

349

1 reference

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16 February 2020

issue

6243

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16 February 2020

page(s)

99-103

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Structural basis of HIV-1 capsid recognition by PF74 and CPSF6.

16 February 2020

cites work

1 reference

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Quantitative microscopy of functional HIV post-entry complexes reveals association of replication with the viral capsid

3 June 2018

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BI-2 destabilizes HIV-1 cores during infection and Prevents Binding of CPSF6 to the HIV-1 Capsid

3 June 2018

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Host cofactors and pharmacologic ligands share an essential interface in HIV-1 capsid that is lost upon disassembly.

3 June 2018

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HIV-1 uncoating: connection to nuclear entry and regulation by host proteins

3 June 2018

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A model for cofactor use during HIV-1 reverse transcription and nuclear entry

3 June 2018

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HIV-1 B-subtype capsid protein: a characterization of amino acid's conservation and its significant association with integrase signatures

3 June 2018

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Nucleoporin NUP153 phenylalanine-glycine motifs engage a common binding pocket within the HIV-1 capsid protein to mediate lentiviral infectivity

3 June 2018

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Structure and Dynamics of Full-Length HIV-1 Capsid Protein in Solution

3 June 2018

1 reference

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Extreme genetic fragility of the HIV-1 capsid.

3 June 2018

1 reference

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Discovery of Novel Small-Molecule HIV-1 Replication Inhibitors That Stabilize Capsid Complexes

3 June 2018

1 reference

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Fitness costs of mutations at the HIV-1 capsid hexamerization interface

3 June 2018

1 reference

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Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamics

3 June 2018

1 reference

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CPSF6 Defines a Conserved Capsid Interface that Modulates HIV-1 Replication

3 June 2018

1 reference

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Protease cleavage leads to formation of mature trimer interface in HIV-1 capsid

3 June 2018

1 reference

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Molecular recognition in the human immunodeficiency virus capsid and antiviral design

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4584149

The interdomain linker region of HIV-1 capsid protein is a critical determinant of proper core assembly and stability

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4584149

REFMAC5 for the refinement of macromolecular crystal structures

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4584149

Overview of the CCP4 suite and current developments

3 June 2018

1 reference

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Atomic-level modelling of the HIV capsid

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4584149

HIV Capsid is a Tractable Target for Small Molecule Therapeutic Intervention

3 June 2018

1 reference

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Virtual screening based identification of novel small-molecule inhibitors targeted to the HIV-1 capsid

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4584149

Structure of the HIV-1 Full-Length Capsid Protein in a Conformationally Trapped Unassembled State Induced by Small-Molecule Binding

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4584149

Small-molecule inhibition of human immunodeficiency virus type 1 infection by virus capsid destabilization

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4584149

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4584149

Structural Convergence between Cryo-EM and NMR Reveals Intersubunit Interactions Critical for HIV-1 Capsid Function

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4584149

X-ray structures of the hexameric building block of the HIV capsid

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4584149

Residues in the HIV-1 capsid assembly inhibitor binding site are essential for maintaining the assembly-competent quaternary structure of the capsid protein

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4584149

Structure of full-length HIV-1 CA: a model for the mature capsid lattice

3 June 2018

1 reference

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Structure of the Antiviral Assembly Inhibitor CAP-1 Complex with the HIV-1 CA Protein

3 June 2018

1 reference

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The effect of capsid mutations on HIV-1 uncoating

3 June 2018

1 reference

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Mutation of dileucine-like motifs in the human immunodeficiency virus type 1 capsid disrupts virus assembly, gag-gag interactions, gag-membrane binding, and virion maturation

3 June 2018

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HKL-3000: the integration of data reduction and structure solution--from diffraction images to an initial model in minutes

3 June 2018

1 reference

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Scaling and assessment of data quality

3 June 2018

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Post-crystallization treatments for improving diffraction quality of protein crystals.

3 June 2018

1 reference

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Coot: model-building tools for molecular graphics

3 June 2018

1 reference

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Assembly properties of the human immunodeficiency virus type 1 CA protein

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4584149

Functional Surfaces of the Human Immunodeficiency Virus Type 1 Capsid Protein

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4584149

PHENIX: building new software for automated crystallographic structure determination

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4584149

Kinetic analysis of the role of intersubunit interactions in human immunodeficiency virus type 1 capsid protein assembly in vitro

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4584149

Formation of a human immunodeficiency virus type 1 core of optimal stability is crucial for viral replication

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4584149

Structures of the HIV-1 capsid protein dimerization domain at 2.6 A resolution

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4584149

Structure of the carboxyl-terminal dimerization domain of the HIV-1 capsid protein

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4584149

The HIV-1 capsid protein C-terminal domain in complex with a virus assembly inhibitor

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4584149

Thermodynamic dissection of a low affinity protein-protein interface involved in human immunodeficiency virus assembly

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4584149

Antiviral inhibition of the HIV-1 capsid protein

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4584149

Structure of the amino-terminal core domain of the HIV-1 capsid protein

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26044298

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Implications for viral capsid assembly from crystal structures of HIV-1 Gag(1-278) and CA(N)(133-278)

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26044298

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCIENCE.AAA5936

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26044298%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26044298%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

PubMed publication ID

26044298

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26044298%20AND%20SRC:MED&resulttype=core&format=json