Prognostication of chronic lymphocytic leukemia in the era of new agents (Q30240258)

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English	Prognostication of chronic lymphocytic leukemia in the era of new agents	scientific article

Statements

instance of

scholarly article

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stated in

Europe PubMed Central

PubMed publication ID

27913474

retrieved

12 June 2017

review article

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Europe PubMed Central

title

Prognostication of chronic lymphocytic leukemia in the era of new agents (English)

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Europe PubMed Central

PubMed publication ID

27913474

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12 June 2017

main subject

lymphocyte

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leukemia

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based on heuristic

inferred from title

chronic lymphocytic leukemia

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based on heuristic

inferred from title

author

Barbara Eichhorst

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1

object named as

Barbara Eichhorst

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Michael Hallek

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2

object named as

Michael Hallek

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stated in

Europe PubMed Central

PubMed publication ID

27913474

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12 June 2017

publication date

1 December 2016

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Europe PubMed Central

PubMed publication ID

27913474

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12 June 2017

published in

Hematology / the Education Program of the American Society of Hematology

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stated in

Europe PubMed Central

PubMed publication ID

27913474

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12 June 2017

volume

2016

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stated in

Europe PubMed Central

PubMed publication ID

27913474

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12 June 2017

issue

1

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Europe PubMed Central

PubMed publication ID

27913474

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12 June 2017

page(s)

149-155

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Europe PubMed Central

PubMed publication ID

27913474

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12 June 2017

cites work

Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemia

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Prolonged lymphocytosis during ibrutinib therapy is associated with distinct molecular characteristics and does not indicate a suboptimal response to therapy

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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A phase 2 study of idelalisib plus rituximab in treatment-naïve older patients with chronic lymphocytic leukemia

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Safety and activity of ibrutinib plus rituximab for patients with high-risk chronic lymphocytic leukaemia: a single-arm, phase 2 study

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Targeting BCL2 with Venetoclax in Relapsed Chronic Lymphocytic Leukemia

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Detailed analysis of therapy-driven clonal evolution of TP53 mutations in chronic lymphocytic leukemia

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Complex karyotypes and KRAS and POT1 mutations impact outcome in CLL after chlorambucil-based chemotherapy or chemoimmunotherapy

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Prognostic nomogram and index for overall survival in previously untreated patients with chronic lymphocytic leukemia

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Validation of the CLL-IPI and comparison with the MDACC prognostic index in newly diagnosed patients.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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The clinical significance of NOTCH1 and SF3B1 mutations in the UK LRF CLL4 trial.

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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NOTCH1 mutations associate with low CD20 level in chronic lymphocytic leukemia: evidence for a NOTCH1 mutation-driven epigenetic dysregulation.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Presence of multiple recurrent mutations confers poor trial outcome of relapsed/refractory CLL.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Ibrutinib combined with bendamustine and rituximab compared with placebo, bendamustine, and rituximab for previously treated chronic lymphocytic leukaemia or small lymphocytic lymphoma (HELIOS): a randomised, double-blind, phase 3 study

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Long-term remissions after FCR chemoimmunotherapy in previously untreated patients with CLL: updated results of the CLL8 trial

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Mutations driving CLL and their evolution in progression and relapse

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Toward a comprehensive prognostic scoring system in chronic lymphocytic leukemia based on a combination of genetic parameters

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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SF3B1 and other novel cancer genes in chronic lymphocytic leukemia

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Mutational Status of the TP53 Gene As a Predictor of Response and Survival in Patients With Chronic Lymphocytic Leukemia: Results From the LRF CLL4 Trial

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Venetoclax in relapsed or refractory chronic lymphocytic leukaemia with 17p deletion: a multicentre, open-label, phase 2 study

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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The evolutionary biography of chronic lymphocytic leukemia

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Evolution and impact of subclonal mutations in chronic lymphocytic leukemia

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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The chronic lymphocytic leukemia international prognostic index predicts time to first treatment in early CLL: Independent validation in a prospective cohort of early stage patients.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Integrated mutational and cytogenetic analysis identifies new prognostic subgroups in chronic lymphocytic leukemia

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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A new prognostic classification of chronic lymphocytic leukemia derived from a multivariate survival analysis

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Ibrutinib for previously untreated and relapsed or refractory chronic lymphocytic leukaemia with TP53 aberrations: a phase 2, single-arm trial

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Development of a comprehensive prognostic index for patients with chronic lymphocytic leukemia

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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ERIC recommendations on TP53 mutation analysis in chronic lymphocytic leukemia

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: association with progression and fludarabine-refractoriness

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Complex karyotype is a stronger predictor than del(17p) for an inferior outcome in relapsed or refractory chronic lymphocytic leukemia patients treated with ibrutinib-based regimens

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Gene mutations and treatment outcome in chronic lymphocytic leukemia: results from the CLL8 trial.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Three-year follow-up of treatment-naïve and previously treated patients with CLL and SLL receiving single-agent ibrutinib

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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TP53, SF3B1, and NOTCH1 mutations and outcome of allotransplantation for chronic lymphocytic leukemia: six-year follow-up of the GCLLSG CLL3X trial

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Acquired mutations in BCL2 family proteins conferring resistance to the BH3 mimetic ABT-199 in lymphoma.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Obinutuzumab plus Chlorambucil in Patients with CLL and Coexisting Conditions

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Eradication of minimal residual disease in B-cell chronic lymphocytic leukemia after alemtuzumab therapy is associated with prolonged survival

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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ATM mutation rather than BIRC3 deletion and/or mutation predicts reduced survival in 11q-deleted chronic lymphocytic leukemia: data from the UK LRF CLL4 trial.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Clinical impact of small TP53 mutated subclones in chronic lymphocytic leukemia

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Mutation status of the residual ATM allele is an important determinant of the cellular response to chemotherapy and survival in patients with chronic lymphocytic leukemia containing an 11q deletion.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Clinical staging of chronic lymphocytic leukemia

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

based on heuristic

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Minimal residual disease quantification is an independent predictor of progression-free and overall survival in chronic lymphocytic leukemia: a multivariate analysis from the randomized GCLLSG CLL8 trial

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Fludarabine, cyclophosphamide, and rituximab treatment achieves long-term disease-free survival in IGHV-mutated chronic lymphocytic leukemia

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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ZAP-70 compared with immunoglobulin heavy-chain gene mutation status as a predictor of disease progression in chronic lymphocytic leukemia

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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On the way towards a 'CLL prognostic index': focus on TP53, BIRC3, SF3B1, NOTCH1 and MYD88 in a population-based cohort

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Disruption of BIRC3 associates with fludarabine chemorefractoriness in TP53 wild-type chronic lymphocytic leukemia.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Should IGHV status and FISH testing be performed in all CLL patients at diagnosis? A systematic review and meta-analysis

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Mutations in TLR/MYD88 pathway identify a subset of young chronic lymphocytic leukemia patients with favorable outcome

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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First-line chemoimmunotherapy with bendamustine and rituximab versus fludarabine, cyclophosphamide, and rituximab in patients with advanced chronic lymphocytic leukaemia (CLL10): an international, open-label, randomised, phase 3, non-inferiority tri

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/27913474

retrieved

12 December 2020

based on heuristic

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Idelalisib and rituximab in relapsed chronic lymphocytic leukemia

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/27913474

retrieved

12 December 2020

based on heuristic

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Ibrutinib versus ofatumumab in previously treated chronic lymphoid leukemia

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

based on heuristic

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ZAP-70 expression as a surrogate for immunoglobulin-variable-region mutations in chronic lymphocytic leukemia.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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MYD88 Mutations and Response to Ibrutinib in Waldenström's Macroglobulinemia

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Prognostic factors in chronic lymphocytic leukemia-what do we need to know?

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Multivariable model for time to first treatment in patients with chronic lymphocytic leukemia

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

based on heuristic

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Resistance mechanisms for the Bruton's tyrosine kinase inhibitor ibrutinib

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Recurrent mutations refine prognosis in chronic lymphocytic leukemia.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Chronic lymphocytic leukemia and treatment resistance in cancer: the role of the p53 pathway

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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An international prognostic index for patients with chronic lymphocytic leukaemia (CLL-IPI): a meta-analysis of individual patient data

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemoimmunotherapy may overcome the adverse prognostic significance of 11q deletion in previously untreated patients with chronic lymphocytic leukemia

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

based on heuristic

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Genomic aberrations and survival in chronic lymphocytic leukemia

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/27913474

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12 December 2020

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Identifiers

DOI

10.1182/ASHEDUCATION-2016.1.149

1 reference

stated in

Europe PubMed Central

PubMed publication ID

27913474

retrieved

12 June 2017

PMC publication ID

6142472

0 references

PubMed publication ID

27913474

1 reference

stated in

Europe PubMed Central

PubMed publication ID

27913474

retrieved

12 June 2017

 

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