Inhibitors of Ras signal transduction as antitumor agents (Q30168731)

9 June 2017

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title

Inhibitors of Ras signal transduction as antitumor agents (English)

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ORCID Public Data File 2021

9 June 2017

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author name string

Garbay C

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9 June 2017

Liu WQ

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9 June 2017

Vidal M

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9 June 2017

Roques BP

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9 June 2017

language of work or name

English

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publication date

1 October 2000

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9 June 2017

published in

Biochemical Pharmacology

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9 June 2017

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9 June 2017

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9 June 2017

page(s)

1165-1169

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The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

9 June 2017

cites work

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The MAPK signaling cascade

7 January 2021

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Mammalian Grb2 regulates multiple steps in embryonic development and malignant transformation.

7 January 2021

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Dominant-negative mutants of Grb2 induced reversal of the transformed phenotypes caused by the point mutation-activated rat HER-2/Neu

7 January 2021

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NMR structure of the N-terminal SH3 domain of GRB2 and its complex with a proline-rich peptide from Sos

7 January 2021

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Solution structure and ligand-binding site of the carboxy-terminal SH3 domain of GRB2

7 January 2021

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Crystal structure of the mammalian Grb2 adaptor

7 January 2021

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DNA polyintercalation: comparison of DNA binding properties of an acridine dimer and trimer

7 January 2021

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Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors

7 January 2021

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Cell internalization of the third helix of the Antennapedia homeodomain is receptor-independent.

7 January 2021

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Inhibition of nuclear translocation of transcription factor NF-kappa B by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence

7 January 2021

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A Truncated HIV-1 Tat Protein Basic Domain Rapidly Translocates through the Plasma Membrane and Accumulates in the Cell Nucleus

7 January 2021

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Structural basis for specificity of Grb2-SH2 revealed by a novel ligand binding mode

7 January 2021

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Discovery of 3-Aminobenzyloxycarbonyl as an N-Terminal Group Conferring High Affinity to the Minimal Phosphopeptide Sequence Recognized by the Grb2-SH2 Domain

7 January 2021

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Small peptides containing phosphotyrosine and adjacent alphaMe-phosphotyrosine or its mimetics as highly potent inhibitors of Grb2 SH2 domain

7 January 2021

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Potent antagonists of the SH2 domain of Grb2: optimization of the X+1 position of 3-amino-Z-Tyr(PO3H2)-X+1-Asn-NH2

7 January 2021

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Src homology-2 domains: structure, mechanisms, and drug discovery

7 January 2021

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Mononucleoside phosphotriester derivatives with S-acyl-2-thioethyl bioreversible phosphate-protecting groups: intracellular delivery of 3'-azido-2',3'-dideoxythymidine 5'-monophosphate

7 January 2021

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Inhibition of the ras-dependent mitogenic pathway by phosphopeptide prodrugs with antiproliferative properties

7 January 2021

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A Sos-derived peptidimer blocks the Ras signaling pathway by binding both Grb2 SH3 domains and displays antiproliferative activity

7 January 2021

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0006-2952(00)00428-7

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9 June 2017

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