Synergistic response to oncogenic mutations defines gene class critical to cancer phenotype. (Q39979160)

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7 January 2020

title

Synergistic response to oncogenic mutations defines gene class critical to cancer phenotype (English)

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7 January 2020

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7 January 2020

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7 January 2020

Erik R Sampson

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7 January 2020

George Compitello

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7 January 2020

Conan Kinsey

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7 January 2020

Laurel Newman

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7 January 2020

Bradley Smith

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7 January 2020

Shaw-Ree Chen

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7 January 2020

Peter Salzman

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7 January 2020

Andrei Yakovlev

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7 January 2020

Hartmut Land

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7 January 2020

language of work or name

English

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publication date

25 May 2008

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7 January 2020

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7 January 2020

volume

453

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issue

7198

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7 January 2020

page(s)

1112-1116

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Impaired host defense in mice lacking ONZIN

7 January 2020

cites work

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Tumor suppressor p53 restricts Ras stimulation of RhoA and cancer cell motility

22 September 2017

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Cancer targets in the Ras pathway

22 September 2017

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A systematic search for downstream mediators of tumor suppressor function of p53 reveals a major role of BTG2 in suppression of Ras-induced transformation

22 September 2017

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Genes that mediate breast cancer metastasis to lung

22 September 2017

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Intrinsic tumour suppression

22 September 2017

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Overexpression of the NOTCH ligand JAG2 in malignant plasma cells from multiple myeloma patients and cell lines.

22 September 2017

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Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis

22 September 2017

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22 September 2017

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Gene expression phenotypic models that predict the activity of oncogenic pathways

22 September 2017

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Notch1 functions as a tumor suppressor in mouse skin

22 September 2017

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Targeting RAS signalling pathways in cancer therapy

22 September 2017

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Fusion of the NUP98 gene and the homeobox gene HOXC13 in acute myeloid leukemia with t(11;12)(p15;q13).

22 September 2017

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Live or let die: the cell's response to p53

22 September 2017

1 reference

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Analysis of the transcriptional program induced by Raf in epithelial cells

22 September 2017

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22 September 2017

Surfing the p53 network

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Genomic analysis of metastasis reveals an essential role for RhoC

22 September 2017

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Analysis of p53-regulated gene expression patterns using oligonucleotide arrays

22 September 2017

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22 September 2017

The Hallmarks of Cancer

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Identification and classification of p53-regulated genes

22 September 2017

1 reference

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Impact of oncogenes in tumor angiogenesis: mutant K-ras up-regulation of vascular endothelial growth factor/vascular permeability factor is necessary, but not sufficient for tumorigenicity of human colorectal carcinoma cells

22 September 2017

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Hoxc13 mutant mice lack external hair

22 September 2017

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High-Intensity Raf Signal Causes Cell Cycle Arrest Mediated by p21Cip1

22 September 2017

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

22 September 2017

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Ras-mediated cell cycle arrest is altered by nuclear oncogenes to induce Schwann cell transformation

22 September 2017

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Rescue of cells from ras oncogene-induced growth arrest by a second, complementing, oncogene

22 September 2017

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Cooperative interaction between c-myc and bcl-2 proto-oncogenes

22 September 2017

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Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway.

22 September 2017

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Onzin, a c-Myc-repressed target, promotes survival and transformation by modulating the Akt-Mdm2-p53 pathway

20 August 2018

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Cooperating oncogenes converge to regulate cyclin/cdk complexes.

20 August 2018

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NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription

20 August 2018

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https://api.crossref.org/works/10.1038%2FNATURE06973

7 January 2021

Establishment of conditionally immortalized epithelial cell lines from both colon and small intestine of adult H-2Kb-tsA58 transgenic mice

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https://api.crossref.org/works/10.1038%2FNATURE06973

7 January 2021

Gene ontology: tool for the unification of biology

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https://api.crossref.org/works/10.1038%2FNATURE06973

7 January 2021

Parallels between global transcriptional programs of polarizing Caco-2 intestinal epithelial cells in vitro and gene expression programs in normal colon and colon cancer

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https://api.crossref.org/works/10.1038%2FNATURE06973

7 January 2021

Multiclass cancer diagnosis using tumor gene expression signatures

1 reference

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7 January 2021

Identifiers

DOI

10.1038/NATURE06973

1 reference

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Dimensions Publication ID

7 January 2020

0 references

1 reference

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7 January 2020

PubMed publication ID

18500333

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18500333%20AND%20SRC:MED&resulttype=core&format=json