Insulin counteracts glucotoxic effects by suppressing thioredoxin-interacting protein production in INS-1E beta cells and in Psammomys obesus pancreatic islets (Q39884233)

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English	Insulin counteracts glucotoxic effects by suppressing thioredoxin-interacting protein production in INS-1E beta cells and in Psammomys obesus pancreatic islets	scientific article

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instance of

scholarly article

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stated in

Europe PubMed Central

PubMed publication ID

19214472

retrieved

15 September 2017

title

Insulin counteracts glucotoxic effects by suppressing thioredoxin-interacting protein production in INS-1E beta cells and in Psammomys obesus pancreatic islets (English)

1 reference

stated in

Europe PubMed Central

PubMed publication ID

19214472

retrieved

15 September 2017

main subject

preproinsulin

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based on heuristic

inferred from title

Sand rat

object named as

Psammomys obesus

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based on heuristic

inferred from title

author name string

M Shaked

series ordinal

1

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Europe PubMed Central

PubMed publication ID

19214472

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15 September 2017

M Ketzinel-Gilad

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2

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stated in

Europe PubMed Central

PubMed publication ID

19214472

retrieved

15 September 2017

Y Ariav

series ordinal

3

1 reference

stated in

Europe PubMed Central

PubMed publication ID

19214472

retrieved

15 September 2017

E Cerasi

series ordinal

4

1 reference

stated in

Europe PubMed Central

PubMed publication ID

19214472

retrieved

15 September 2017

N Kaiser

series ordinal

5

1 reference

stated in

Europe PubMed Central

PubMed publication ID

19214472

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15 September 2017

G Leibowitz

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6

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stated in

Europe PubMed Central

PubMed publication ID

19214472

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15 September 2017

publication date

13 February 2009

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Europe PubMed Central

PubMed publication ID

19214472

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15 September 2017

published in

Diabetologia

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stated in

Europe PubMed Central

PubMed publication ID

19214472

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15 September 2017

volume

52

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stated in

Europe PubMed Central

PubMed publication ID

19214472

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15 September 2017

issue

4

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Europe PubMed Central

PubMed publication ID

19214472

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15 September 2017

page(s)

636-644

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Europe PubMed Central

PubMed publication ID

19214472

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15 September 2017

cites work

Glucotoxicity and beta-cell failure in type 2 diabetes mellitus

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Crossref

reference URL

https://api.crossref.org/works/10.1007%2FS00125-009-1274-2

retrieved

21 January 2018

Distinct pathways of insulin-regulated versus diabetes-regulated gene expression: an in vivo analysis in MIRKO mice

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19214472

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucolipotoxicity: fuel excess and beta-cell dysfunction.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19214472

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thioredoxin-interacting protein deficiency induces Akt/Bcl-xL signaling and pancreatic beta-cell mass and protects against diabetes

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19214472

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exenatide inhibits beta-cell apoptosis by decreasing thioredoxin-interacting protein

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19214472

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperglycemia promotes oxidative stress through inhibition of thioredoxin function by thioredoxin-interacting protein

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19214472

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Redox control of exocytosis: regulatory role of NADPH, thioredoxin, and glutaredoxin

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19214472

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid induction and Ca(2+) influx-mediated suppression of vitamin D3 up-regulated protein 1 (VDUP1) mRNA in cerebellar granule neurons undergoing apoptosis

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19214472

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High glucose-induced thioredoxin-interacting protein in renal proximal tubule cells is independent of transforming growth factor-beta1.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19214472

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12 December 2020

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inferred from PubMed ID database lookup

Thioredoxin-interacting protein (Txnip) is a critical regulator of hepatic glucose production

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19214472

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monolayer culture of adult rat pancreatic islets on extracellular matrix: long term maintenance of differentiated B-cell function

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19214472

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thioredoxin-interacting protein is stimulated by glucose through a carbohydrate response element and induces beta-cell apoptosis

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19214472

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diazoxide-induced beta-cell rest reduces endoplasmic reticulum stress in lipotoxic beta-cells

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19214472

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12 December 2020

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inferred from PubMed ID database lookup

Nitric oxide-dependent suppression of thioredoxin-interacting protein expression enhances thioredoxin activity

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19214472

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19214472

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The importance of the beta-cell in the pathogenesis of type 2 diabetes mellitus

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19214472

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of ARNT/HIF1beta mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19214472

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Txnip balances metabolic and growth signaling via PTEN disulfide reduction

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19214472

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction between genetic and dietary factors determines beta-cell function in Psammomys obesus, an animal model of type 2 diabetes.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19214472

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Minireview: Secondary beta-cell failure in type 2 diabetes--a convergence of glucotoxicity and lipotoxicity

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19214472

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted deletion of thioredoxin-interacting protein regulates cardiac dysfunction in response to pressure overload

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19214472

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A combination of genomic approaches reveals the role of FOXO1a in regulating an oxidative stress response pathway

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19214472

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TXNIP regulates peripheral glucose metabolism in humans

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19214472

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide mediates the survival action of IGF-1 and insulin in pancreatic beta cells

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19214472

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperglycemia regulates thioredoxin-ROS activity through induction of thioredoxin-interacting protein (TXNIP) in metastatic breast cancer-derived cells MDA-MB-231.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19214472

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of thioredoxin in cell growth through interactions with signaling molecules

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19214472

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

All roads lead to FoxO.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19214472

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The islet in type 2 diabetes: back to center stage

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19214472

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-cell glucose toxicity, lipotoxicity, and chronic oxidative stress in type 2 diabetes

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19214472

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thioredoxin-interacting protein: a critical link between glucose toxicity and beta-cell apoptosis

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19214472

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Islet beta cell failure in type 2 diabetes

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19214472

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin deficiency and insulin resistance in type 2 (non-insulin-dependent) diabetes: quantitative contributions of pancreatic and peripheral responses to glucose homeostasis

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19214472

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The interaction of thioredoxin with Txnip. Evidence for formation of a mixed disulfide by disulfide exchange

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19214472

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1007/S00125-009-1274-2

1 reference

stated in

Europe PubMed Central

PubMed publication ID

19214472

retrieved

15 September 2017

PubMed publication ID

19214472

1 reference

stated in

Europe PubMed Central

PubMed publication ID

19214472

retrieved

15 September 2017

ResearchGate publication ID

24005495

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