Osteopontin promotes gastric cancer metastasis by augmenting cell survival and invasion through Akt-mediated HIF-1alpha up-regulation and MMP9 activation (Q39825484)

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scientific article published in August 2009

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English	Osteopontin promotes gastric cancer metastasis by augmenting cell survival and invasion through Akt-mediated HIF-1alpha up-regulation and MMP9 activation	scientific article published in August 2009

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6512381

Osteopontin promotes gastric cancer metastasis by augmenting cell survival and invasion through Akt-mediated HIF-1alpha up-regulation and MMP9 activation (English)

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6512381

cancer metastasis

1 reference

based on heuristic

inferred from title

author name string

Gang Song

1

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6512381

Gaoliang Ouyang

2

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6512381

Yubin Mao

3

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6512381

Yanlin Ming

4

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6512381

Shideng Bao

5

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6512381

Tianhui Hu

6

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6512381

publication date

1 August 2009

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Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6512381

Journal of Cellular and Molecular Medicine

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Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6512381

13

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6512381

8B

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6512381

1706-1718

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6512381

Role of osteopontin in tumour progression

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00540.X

21 January 2018

Osteopontin: role in cell signaling and cancer progression

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00540.X

21 January 2018

The multifaceted roles of osteopontin in cell signaling, tumor progression and angiogenesis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00540.X

21 January 2018

Osteopontin: regulation in tumor metastasis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00540.X

21 January 2018

Increased expression of osteopontin contributes to the progression of prostate cancer

1 reference

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21 January 2018

Overexpression of osteopontin is associated with intrahepatic metastasis, early recurrence, and poorer prognosis of surgically resected hepatocellular carcinoma.

1 reference

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21 January 2018

Osteopontin identified as lead marker of colon cancer progression, using pooled sample expression profiling

1 reference

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21 January 2018

Osteopontin as a potential diagnostic biomarker for ovarian cancer

1 reference

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21 January 2018

Receptor-ligand interaction between CD44 and osteopontin (Eta-1)

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00540.X

21 January 2018

Osteopontin induces AP-1-mediated secretion of urokinase-type plasminogen activator through c-Src-dependent epidermal growth factor receptor transactivation in breast cancer cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00540.X

21 January 2018

Nuclear factor-inducing kinase plays a crucial role in osteopontin-induced MAPK/IkappaBalpha kinase-dependent nuclear factor kappaB-mediated promatrix metalloproteinase-9 activation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00540.X

21 January 2018

The osteopontin-CD44 survival signal involves activation of the phosphatidylinositol 3-kinase/Akt signaling pathway

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00540.X

21 January 2018

Osteopontin stimulates cell motility and nuclear factor kappaB-mediated secretion of urokinase type plasminogen activator through phosphatidylinositol 3-kinase/Akt signaling pathways in breast cancer cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00540.X

21 January 2018

Periostin potently promotes metastatic growth of colon cancer by augmenting cell survival via the Akt/PKB pathway

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00540.X

21 January 2018

Hypoxia-inducible factor 1: regulation by hypoxic and non-hypoxic activators

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00540.X

21 January 2018

Hypoxia--a key regulatory factor in tumour growth

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00540.X

21 January 2018

The MAPK pathway and HIF-1 are involved in the induction of the human PAI-1 gene expression by insulin in the human hepatoma cell line HepG2.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00540.X

21 January 2018

Lack of evidence for the involvement of the phosphoinositide 3-kinase/Akt pathway in the activation of hypoxia-inducible factors by low oxygen tension.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00540.X

21 January 2018

Phosphatidylinositol 3-kinase/Akt signaling is neither required for hypoxic stabilization of HIF-1 alpha nor sufficient for HIF-1-dependent target gene transcription

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00540.X

21 January 2018

Global cancer statistics, 2002

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00540.X

21 January 2018

Identification of genes differentially expressed between gastric cancers and normal gastric mucosa with cDNA microarrays

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00540.X

21 January 2018

Metastases-related genes in the classification of liver and peritoneal metastasis in human gastric cancer

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00540.X

21 January 2018

Elevated plasma osteopontin associated with gastric cancer development, invasion and survival.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00540.X

21 January 2018

Cellular prion protein promotes proliferation and G1/S transition of human gastric cancer cells SGC7901 and AGS.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00540.X

21 January 2018

Curcumin induces human HT-29 colon adenocarcinoma cell apoptosis by activating p53 and regulating apoptosis-related protein expression

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00540.X

21 January 2018

Osteopontin stimulates tumor growth and activation of promatrix metalloproteinase-2 through nuclear factor-kappa B-mediated induction of membrane type 1 matrix metalloproteinase in murine melanoma cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00540.X

21 January 2018

Anti-proliferation and apoptosis induced by a novel intestinal metabolite of ginseng saponin in human hepatocellular carcinoma cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00540.X

21 January 2018

Growth factor signaling induces metastasis genes in transformed cells: molecular connection between Akt kinase and osteopontin in breast cancer

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00540.X

21 January 2018

Molecular mechanisms of tumor angiogenesis and tumor progression

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00540.X

21 January 2018

Biology of HIF-1alpha

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00540.X

21 January 2018

Direct regulation of TWIST by HIF-1alpha promotes metastasis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00540.X

21 January 2018

A biochemical characterization of the binding of osteopontin to integrins alpha v beta 1 and alpha v beta 5

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00540.X

21 January 2018

Osteopontin increases CD44 expression and cell adhesion in RAW 264.7 murine leukemia cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00540.X

21 January 2018

Expression profiling reveals genes associated with transendothelial migration of tumor cells: a functional role for alphavbeta3 integrin.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00540.X

21 January 2018

Abrogation of the interaction between osteopontin and alphavbeta3 integrin reduces tumor growth of human lung cancer cells in mice.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00540.X

21 January 2018

Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics

1 reference

https://pubmed.ncbi.nlm.nih.gov/19602039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated serum bone sialoprotein and osteopontin in colon, breast, prostate, and lung cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19602039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The metastasis gene osteopontin: a candidate target for cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19602039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The relationship between bone metastasis from human breast cancer and integrin alpha(v)beta3 expression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19602039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical implications of osteopontin in metastatic lesions of uterine cervical cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/19602039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Osteopontin promotes integrin activation through outside-in and inside-out mechanisms: OPN-CD44V interaction enhances survival in gastrointestinal cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19602039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic significance of osteopontin expression in human gastric carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19602039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein expression of osteopontin in tumor tissues is an independent prognostic indicator in gastric cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19602039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recognition of osteopontin and related peptides by an alpha v beta 3 integrin stimulates immediate cell signals in osteoclasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/19602039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rapid in vitro assay for quantitating the invasive potential of tumor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19602039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Osteopontin expression in lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19602039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Osteopontin expression in a group of lymph node negative breast cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19602039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1582-4934.2008.00540.X

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6512381

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6512381

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6512381

ResearchGate publication ID

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