HBx targeting to mitochondria and ROS generation are necessary but insufficient for HBV-induced cyclooxygenase-2 expression. (Q39770358)

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English	HBx targeting to mitochondria and ROS generation are necessary but insufficient for HBV-induced cyclooxygenase-2 expression.	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

19940973

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19940973%20AND%20SRC:MED&resulttype=core&format=json

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12 February 2020

title

HBx targeting to mitochondria and ROS generation are necessary but insufficient for HBV-induced cyclooxygenase-2 expression (English)

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stated in

Europe PubMed Central

PubMed publication ID

19940973

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19940973%20AND%20SRC:MED&resulttype=core&format=json

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12 February 2020

main subject

mitochondrion

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author

Wang-Shick Ryu

series ordinal

6

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Europe PubMed Central

PubMed publication ID

19940973

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19940973%20AND%20SRC:MED&resulttype=core&format=json

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12 February 2020

author name string

Wonchung Lim

series ordinal

1

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stated in

Europe PubMed Central

PubMed publication ID

19940973

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19940973%20AND%20SRC:MED&resulttype=core&format=json

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12 February 2020

Soon-Hwan Kwon

series ordinal

2

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Europe PubMed Central

PubMed publication ID

19940973

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19940973%20AND%20SRC:MED&resulttype=core&format=json

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12 February 2020

Hyeseon Cho

series ordinal

3

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Europe PubMed Central

PubMed publication ID

19940973

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19940973%20AND%20SRC:MED&resulttype=core&format=json

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12 February 2020

Sujeong Kim

series ordinal

4

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Europe PubMed Central

PubMed publication ID

19940973

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19940973%20AND%20SRC:MED&resulttype=core&format=json

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12 February 2020

Seungmin Lee

series ordinal

5

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Europe PubMed Central

PubMed publication ID

19940973

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19940973%20AND%20SRC:MED&resulttype=core&format=json

retrieved

12 February 2020

Hyeseong Cho

series ordinal

7

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stated in

Europe PubMed Central

PubMed publication ID

19940973

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19940973%20AND%20SRC:MED&resulttype=core&format=json

retrieved

12 February 2020

publication date

26 November 2009

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Europe PubMed Central

PubMed publication ID

19940973

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19940973%20AND%20SRC:MED&resulttype=core&format=json

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12 February 2020

published in

Journal of Molecular Medicine

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stated in

Europe PubMed Central

PubMed publication ID

19940973

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19940973%20AND%20SRC:MED&resulttype=core&format=json

retrieved

12 February 2020

volume

88

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Europe PubMed Central

PubMed publication ID

19940973

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19940973%20AND%20SRC:MED&resulttype=core&format=json

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12 February 2020

issue

4

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Europe PubMed Central

PubMed publication ID

19940973

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19940973%20AND%20SRC:MED&resulttype=core&format=json

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12 February 2020

page(s)

359-369

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stated in

Europe PubMed Central

PubMed publication ID

19940973

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19940973%20AND%20SRC:MED&resulttype=core&format=json

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12 February 2020

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Activation of Src Family Kinases by Hepatitis B Virus HBx Protein and Coupled Signaling to Ras

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Self-association and precursor protein binding of Saccharomyces cerevisiae Tom40p, the core component of the protein translocation channel of the mitochondrial outer membrane

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12 December 2020

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Hepatitis B virus X protein induces cell death by causing loss of mitochondrial membrane potential

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PubMed

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12 December 2020

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Reactive oxygen species from mitochondria induce cyclooxygenase-2 gene expression in human mesangial cells: potential role in diabetic nephropathy

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/19940973

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12 December 2020

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Hepatitis C Virus Stimulates the Expression of Cyclooxygenase-2 via Oxidative Stress: Role of Prostaglandin E2 in RNA Replication

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https://pubmed.ncbi.nlm.nih.gov/19940973

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12 December 2020

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Hepatitis B virus X protein colocalizes to mitochondria with a human voltage-dependent anion channel, HVDAC3, and alters its transmembrane potential

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https://pubmed.ncbi.nlm.nih.gov/19940973

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12 December 2020

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Hepatitis B virus x protein induces perinuclear mitochondrial clustering in microtubule- and Dynein-dependent manners

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12 December 2020

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Expression of mitogen-inducible cyclooxygenase induced by lipopolysaccharide: mediation through both mitogen-activated protein kinase and NF-kappaB signaling pathways in macrophages

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https://pubmed.ncbi.nlm.nih.gov/19940973

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12 December 2020

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Hepatocellular carcinoma: epidemiology, risk factors, and screening

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https://pubmed.ncbi.nlm.nih.gov/19940973

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12 December 2020

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Mitochondrially associated hepatitis B virus X protein constitutively activates transcription factors STAT-3 and NF-kappa B via oxidative stress

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19940973

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12 December 2020

based on heuristic

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Human hepatitis B virus-X protein alters mitochondrial function and physiology in human liver cells

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19940973

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatitis B virus X protein stimulates the mitochondrial translocation of Raf-1 via oxidative stress

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19940973

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endoplasmic reticulum stress stimulates the expression of cyclooxygenase-2 through activation of NF-kappaB and pp38 mitogen-activated protein kinase

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/19940973

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12 December 2020

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Nuclear factor-kappaB and the hepatic inflammation-fibrosis-cancer axis

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PubMed

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12 December 2020

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p38/NF-kB-dependent expression of COX-2 during differentiation and inflammatory response of chondrocytes

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/19940973

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12 December 2020

based on heuristic

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Calcium signaling by HBx protein in hepatitis B virus DNA replication

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/19940973

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12 December 2020

based on heuristic

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Characterization of the signal that directs Bcl-x(L), but not Bcl-2, to the mitochondrial outer membrane

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/19940973

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12 December 2020

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IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/19940973

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HBV induced carcinogenesis

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/19940973

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation and inhibition of cellular calcium and tyrosine kinase signaling pathways identify targets of the HBx protein involved in hepatitis B virus replication

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/19940973

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of cyclooxygenase-2 in chronic hepatitis B and the effects of anti-viral therapy.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/19940973

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclooxygenase-2 overexpression enhances lymphatic invasion and metastasis in human gastric carcinoma

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/19940973

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of hepatitis B virus X protein with mitochondria causes mitochondrial aggregation at the nuclear periphery, leading to cell death

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19940973

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constitutive expression of the cyclooxygenase-2 gene in T-cell lines infected with human T cell leukemia virus type I.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19940973

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of cyclooxygenase 2 and cytosolic phospholipase A(2) in the liver tissue of patients with chronic hepatitis and liver cirrhosis

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19940973

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The hepatitis B virus X protein up-regulates tumor necrosis factor alpha gene expression in hepatocytes.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19940973

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of hepatitis B virus genome replication by HBx is linked to both nuclear and cytoplasmic HBx expression

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19940973

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human interleukin 6 gene is activated by hepatitis B virus-X protein in human hepatoma cells.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19940973

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of constitutive (COX-1) and inducible (COX-2) cyclooxygenase in postviral human liver cirrhosis: a possible role for COX-2 in the pathogenesis of liver cirrhosis.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19940973

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The enigmatic X gene of hepatitis B virus

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19940973

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Up-regulation of p300 binding and p50 acetylation in tumor necrosis factor-alpha-induced cyclooxygenase-2 promoter activation

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19940973

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role and regulation of COX-2 during viral infection

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19940973

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative damage is increased in human liver tissue adjacent to hepatocellular carcinoma

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19940973

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1007/S00109-009-0563-Z

1 reference

stated in

Europe PubMed Central

PubMed publication ID

19940973

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19940973%20AND%20SRC:MED&resulttype=core&format=json

retrieved

12 February 2020

PubMed publication ID

19940973

1 reference

stated in

Europe PubMed Central

PubMed publication ID

19940973

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19940973%20AND%20SRC:MED&resulttype=core&format=json

retrieved

12 February 2020

 

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