Proteins required for centrosome clustering in cancer cells. (Q39699958)

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3 February 2020

title

Proteins required for centrosome clustering in cancer cells (English)

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Blanka Leber

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Bettina Maier

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3 February 2020

Florian Fuchs

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3 February 2020

Jing Chi

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Phillip Riffel

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Simon Anderhub

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Ludmila Wagner

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Anthony D Ho

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Jeffrey L Salisbury

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Alwin Krämer

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3 February 2020

language of work or name

English

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publication date

1 May 2010

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Science Translational Medicine

3 February 2020

published in

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volume

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issue

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page(s)

33ra38

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Re-evaluating centrosome function

3 February 2020

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Centrosome hypertrophy in human breast tumors: Implications for genomic stability and cell polarity

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Centrosome aberrations: cause or consequence of cancer progression?

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Formation of the tetraploid intermediate is associated with the development of cells with more than four centrioles in the elastase-simian virus 40 tumor antigen transgenic mouse model of pancreatic cancer.

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Oncogenes and tumour suppressors take on centrosomes

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Identification of griseofulvin as an inhibitor of centrosomal clustering in a phenotype-based screen

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A mechanism linking extra centrosomes to chromosomal instability

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Spindle multipolarity is prevented by centrosomal clustering.

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Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes

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HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity

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The ch-TOG/XMAP215 protein is essential for spindle pole organization in human somatic cells

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Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells

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Chromosomal passengers: conducting cell division

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Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores

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Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle

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Uncoupling the central spindle-associated function of the chromosomal passenger complex from its role at centromeres

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The Ndc80/HEC1 complex is a contact point for kinetochore-microtubule attachment

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CCAN makes multiple contacts with centromeric DNA to provide distinct pathways to the outer kinetochore

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Kinetochore microtubule dynamics and attachment stability are regulated by Hec1

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Sensing chromosome bi-orientation by spatial separation of aurora B kinase from kinetochore substrates

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Vertebrate shugoshin links sister centromere cohesion and kinetochore microtubule stability in mitosis

21 January 2018

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Sororin is required for stable binding of cohesin to chromatin and for sister chromatid cohesion in interphase

21 January 2018

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The centromeric protein Sgo1 is required to sense lack of tension on mitotic chromosomes

21 January 2018

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sSgo1, a major splice variant of Sgo1, functions in centriole cohesion where it is regulated by Plk1

21 January 2018

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Studies of haspin-depleted cells reveal that spindle-pole integrity in mitosis requires chromosome cohesion

21 January 2018

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FAM29A promotes microtubule amplification via recruitment of the NEDD1-gamma-tubulin complex to the mitotic spindle

21 January 2018

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The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells

21 January 2018

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Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution

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Cep164, a novel centriole appendage protein required for primary cilium formation

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Bir1 is required for the tension checkpoint

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The vertebrate Ndc80 complex contains Spc24 and Spc25 homologs, which are required to establish and maintain kinetochore-microtubule attachment

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21 January 2018

Identifiers

DOI

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3 February 2020

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