Novel small molecule drugs inhibit tumor cell metabolism and show potent anti-tumorigenic potential (Q39654034)

13 September 2017

title

Novel small molecule drugs inhibit tumor cell metabolism and show potent anti-tumorigenic potential (English)

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13 September 2017

author name string

Christina Trojel-Hansen

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13 September 2017

Kamille Dumong Erichsen

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13 September 2017

Mette Knak Christensen

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13 September 2017

Peter Buhl Jensen

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13 September 2017

Maxwell Sehested

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13 September 2017

Søren Jensby Nielsen

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13 September 2017

language of work or name

English

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20852860

16 July 2024

publication date

18 September 2010

1 reference

full work available at URL

13 September 2017

https://hal.archives-ouvertes.fr/hal-00624467/file/PEER_stage2_10.1007%252Fs00280-010-1453-3.pdf

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20852860

http://link.springer.com/content/pdf/10.1007/s00280-010-1453-3.pdf

16 July 2024

1 reference

https://api.crossref.org/works/10.1007/S00280-010-1453-3

http://link.springer.com/article/10.1007/s00280-010-1453-3/fulltext.html

16 July 2024

1 reference

https://api.crossref.org/works/10.1007/S00280-010-1453-3

http://link.springer.com/content/pdf/10.1007/s00280-010-1453-3

16 July 2024

1 reference

DOI

https://api.crossref.org/works/10.1007/S00280-010-1453-3

Cancer Chemotherapy and Pharmacology

16 July 2024

published in

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13 September 2017

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13 September 2017

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13 September 2017

page(s)

127-138

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Nutritional control of gene expression: how mammalian cells respond to amino acid limitation

13 September 2017

cites work

1 reference

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Tumor cell metabolism: cancer's Achilles' heel

21 January 2018

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The GCN2 eIF2alpha kinase is required for adaptation to amino acid deprivation in mice

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21 January 2018

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The TSC1-TSC2 complex is required for proper activation of mTOR complex 2

21 January 2018

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The TSC1-TSC2 complex: a molecular switchboard controlling cell growth

21 January 2018

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Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism

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The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

21 January 2018

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Rag proteins regulate amino-acid-induced mTORC1 signalling.

21 January 2018

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Amino acid availability regulates p70 S6 kinase and multiple translation factors

21 January 2018

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eIF-2 kinases: regulators of general and gene-specific translation initiation

21 January 2018

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The histidyl-tRNA synthetase-related sequence in the eIF-2 alpha protein kinase GCN2 interacts with tRNA and is required for activation in response to starvation for different amino acids

21 January 2018

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Syntheses and antiproliferative evaluation of oxyphenisatin derivatives

21 January 2018

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Inter-experiment variation and dependence on culture conditions in assaying the chemosensitivity of human small cell lung cancer cell lines.

21 January 2018

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The Hallmarks of Cancer

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Understanding the Warburg effect: the metabolic requirements of cell proliferation

21 January 2018

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Bidirectional transport of amino acids regulates mTOR and autophagy

21 January 2018

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IRS-1: auditing the effectiveness of mTOR inhibitors

21 January 2018

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mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt

21 January 2018

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Rapamycin induces feedback activation of Akt signaling through an IGF-1R-dependent mechanism

21 January 2018

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New functions for amino acids: effects on gene transcription and translation

21 January 2018

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16 July 2024

Identifiers

DOI

1 reference

13 September 2017

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