GH-Dependent STAT5 Signaling Plays an Important Role in Hepatic Lipid Metabolism (Q39630577)

13 September 2017

title

GH-dependent STAT5 signaling plays an important role in hepatic lipid metabolism (English)

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

13 September 2017

GH-Dependent STAT5 Signaling Plays an Important Role in Hepatic Lipid Metabolism (English)

1 reference

28 August 2024

Johanna L. Barclay

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21084450

28 August 2024

Elizabeth E. Powell

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21084450

28 August 2024

Mayumi Ishikawa

1 reference

13 September 2017

Caroline N. Nelson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21084450

28 August 2024

Lauren A. Murray

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21084450

28 August 2024

Linda M. Kerr

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21084450

28 August 2024

Timothy R. McPhee

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21084450

28 August 2024

Michael J. Waters

1 reference

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28 August 2024

language of work or name

English

0 references

publication date

17 November 2010

1 reference

full work available at URL

13 September 2017

1 reference

inferred from page(s)

https://academic.oup.com/endo/article-pdf/152/1/181/9010524/endo0181.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21084450

http://intl-endo.endojournals.org/cgi/content/abstract/152/1/181

28 August 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21084450

http://academic.oup.com/endo/article-pdf/152/1/181/9010524/endo0181.pdf

28 August 2024

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

28 August 2024

1 reference

13 September 2017

volume

152

1 reference

13 September 2017

1 reference

13 September 2017

page(s)

181-192

1 reference

Molecular mechanisms and therapeutic targets in steatosis and steatohepatitis

13 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Transcriptional regulation of metabolism

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Biological effects of growth hormone on carbohydrate and lipid metabolism.

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Adipocytokines and the regulation of lipid metabolism in growth hormone transgenic and calorie-restricted mice.

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Nonalcoholic fatty liver disease among patients with hypothalamic and pituitary dysfunction

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Non-alcoholic steatohepatitis and hepatic steatosis in patients with adult onset growth hormone deficiency

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Metabolic co-morbidities revealed in patients with childhood-onset adult GH deficiency after cessation of GH replacement therapy for short stature

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Growth Hormone Reverses Nonalcoholic Steatohepatitis in a Patient With Adult Growth Hormone Deficiency

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Nonalcoholic fatty liver in patients with Laron syndrome and GH gene deletion - preliminary report

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Comparing adiposity profiles in three mouse models with altered GH signaling

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse)

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Liver-specific deletion of the growth hormone receptor reveals essential role of growth hormone signaling in hepatic lipid metabolism

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Signaling pathways activated by the growth hormone receptor

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

An agonist-induced conformational change in the growth hormone receptor determines the choice of signalling pathway.

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

How growth hormone controls growth, obesity and sexual dimorphism

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Growth hormone regulation of sex-dependent liver gene expression

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Sex-dependent liver gene expression is extensive and largely dependent upon signal transducer and activator of transcription 5b (STAT5b): STAT5b-dependent activation of male genes and repression of female genes revealed by microarray analysis.

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

In vivo analysis of growth hormone receptor signaling domains and their associated transcripts

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

In vivo targeting of the growth hormone receptor (GHR) Box1 sequence demonstrates that the GHR does not signal exclusively through JAK2.

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Inactivation of Stat5 in mouse mammary epithelium during pregnancy reveals distinct functions in cell proliferation, survival, and differentiation

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Determining hepatic triglyceride production in mice: comparison of poloxamer 407 with Triton WR-1339.

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

SOCS3 as a tumor suppressor in breast cancer cells, and its regulation by PRL.

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Third promoter and differential regulation of mouse and human fatty acid translocase/CD36 genes

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Synergistic action of hepatocyte nuclear factors 3 and 6 on CYP2C12 gene expression and suppression by growth hormone-activated STAT5b. Proposed model for female specific expression of CYP2C12 in adult rat liver

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Genomic dissection of the cytokine-controlled STAT5 signaling network in liver

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Loss of signal transducer and activator of transcription 5 leads to hepatosteatosis and impaired liver regeneration

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Interaction between growth hormone and insulin in the regulation of lipoprotein metabolism in the rat.

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Simultaneous, bidirectional inhibitory crosstalk between PPAR and STAT5b

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

The regulation of fatty acid synthase by STAT5A.

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Profiles of growth hormone (GH)-regulated genes reveal time-dependent responses and identify a mechanism for regulation of activating transcription factor 3 by GH.

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

STAT3 activation is required for Asp(816) mutant c-Kit induced tumorigenicity

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Unphosphorylated STAT1 prolongs the expression of interferon-induced immune regulatory genes

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Adipocyte-specific gene expression and adipogenic steatosis in the mouse liver due to peroxisome proliferator-activated receptor gamma1 (PPARgamma1) overexpression

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass.

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Stearoyl-CoA desaturase 2 is required for peroxisome proliferator-activated receptor gamma expression and adipogenesis in cultured 3T3-L1 cells

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Multiple expression control mechanisms of peroxisome proliferator-activated receptors and their target genes

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARgamma in promoting steatosis

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Differential expression and activation of a family of murine peroxisome proliferator-activated receptors

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Lipid metabolism and liver inflammation. I. Hepatic fatty acid uptake: possible role in steatosis.

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Increased hepatic CD36 expression contributes to dyslipidemia associated with diet-induced obesity

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

A novel pregnane X receptor-mediated and sterol regulatory element-binding protein-independent lipogenic pathway

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Lipoprotein lipase expression in livers of morbidly obese patients could be responsible for liver steatosis

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Genes involved in fatty acid partitioning and binding, lipolysis, monocyte/macrophage recruitment, and inflammation are overexpressed in the human fatty liver of insulin-resistant subjects.

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Reversal of hypercholesterolemia in low density lipoprotein receptor knockout mice by adenovirus-mediated gene transfer of the very low density lipoprotein receptor

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

The VLDL receptor plays a major role in chylomicron metabolism by enhancing LPL-mediated triglyceride hydrolysis

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

Loss of STAT5 causes liver fibrosis and cancer development through increased TGF-{beta} and STAT3 activation.

28 August 2024

1 reference

https://api.crossref.org/works/10.1210/EN.2010-0537

28 August 2024

Identifiers

DOI

10.1210/EN.2010-0537

1 reference

13 September 2017

1 reference