Bufadienolide compounds sensitize human breast cancer cells to TRAIL-induced apoptosis via inhibition of STAT3/Mcl-1 pathway (Q39603958)

13 September 2017

title

Bufadienolide compounds sensitize human breast cancer cells to TRAIL-induced apoptosis via inhibition of STAT3/Mcl-1 pathway (English)

1 reference

13 September 2017

Yinhui Dong

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13 September 2017

Shutao Yin

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13 September 2017

Jinghua Li

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13 September 2017

Cheng Jiang

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13 September 2017

Min Ye

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13 September 2017

Hongbo Hu

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13 September 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21259053

22 November 2024

publication date

1 April 2011

1 reference

13 September 2017

April 2011

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21259053

full work available at URL

22 November 2024

http://link.springer.com/content/pdf/10.1007/s10495-011-0573-5.pdf

file format

Portable Document Format

1 reference

DOI

https://api.crossref.org/works/10.1007/S10495-011-0573-5

http://link.springer.com/article/10.1007/s10495-011-0573-5/fulltext.html

22 November 2024

1 reference

https://api.crossref.org/works/10.1007/S10495-011-0573-5

http://link.springer.com/content/pdf/10.1007/s10495-011-0573-5

22 November 2024

1 reference

DOI

https://api.crossref.org/works/10.1007/S10495-011-0573-5

22 November 2024

1 reference

13 September 2017

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13 September 2017

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13 September 2017

page(s)

394-403

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Death receptors: signaling and modulation

13 September 2017

cites work

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Selective inhibitory effect of bufalin on growth of human tumor cells in vitro: association with the induction of apoptosis in leukemia HL-60 cells

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The cooperative interaction of two different signaling pathways in response to bufalin induces apoptosis in human leukemia U937 cells

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Apoptotic signaling in bufalin- and cinobufagin-treated androgen-dependent and -independent human prostate cancer cells

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Antiproliferative activity of derivatives of ouabain, digoxin and proscillaridin A in human MCF-7 and MDA-MB-231 breast cancer cells

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Involvement of caspase-3 activity and survivin downregulation in cinobufocini-induced apoptosis in A 549 cells

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Involvement of caspases and apoptosis-inducing factor in bufotalin-induced apoptosis of Hep 3B cells

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PI3K/Akt is involved in bufalin-induced apoptosis in gastric cancer cells

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Anti-tumor activities and apoptosis-regulated mechanisms of bufalin on the orthotopic transplantation tumor model of human hepatocellular carcinoma in nude mice.

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Inorganic selenium sensitizes prostate cancer cells to TRAIL-induced apoptosis through superoxide/p53/Bax-mediated activation of mitochondrial pathway

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Hypoxia-inducible factor-1-dependent overexpression of myeloid cell factor-1 protects hypoxic cells against tert-butyl hydroperoxide-induced apoptosis

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At the gates of death

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Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells

21 January 2018

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Expression of SOCS1 and SOCS3 genes is differentially regulated in breast cancer cells in response to proinflammatory cytokine and growth factor signals.

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Triple-negative breast cancers: a view from 10,000 feet

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TRAIL induces apoptosis in triple-negative breast cancer cells with a mesenchymal phenotype

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Mitochondria from TRAIL-resistant prostate cancer cells are capable of responding to apoptotic stimuli

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A mitochondrial block and expression of XIAP lead to resistance to TRAIL-induced apoptosis during progression to metastasis of a colon carcinoma

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21 January 2018

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Reduction of TRAIL-induced Mcl-1 and cIAP2 by c-Myc or sorafenib sensitizes resistant human cancer cells to TRAIL-induced death.

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Antisense strategy shows that Mcl-1 rather than Bcl-2 or Bcl-x(L) is an essential survival protein of human myeloma cells.

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21 January 2018

Identifiers

DOI

1 reference

13 September 2017

1 reference