PB1-mediated virulence attenuation of H5N1 influenza virus in mice is associated with PB2 (Q39582914)

13 September 2017

title

PB1-mediated virulence attenuation of H5N1 influenza virus in mice is associated with PB2 (English)

1 reference

Crossref

DOI

https://api.crossref.org/works/10.1099/VIR.0.030718-0

25 November 2024

Yi Hu

1 reference

13 September 2017

Jing Li

1 reference

13 September 2017

Yongqiang Li

1 reference

13 September 2017

Guohui Chang

1 reference

13 September 2017

Wei Sun

1 reference

13 September 2017

Yinhui Yang

1 reference

13 September 2017

Xiaoping Kang

1 reference

13 September 2017

Xiaoyan Wu

1 reference

13 September 2017

Qingyu Zhu

1 reference

13 September 2017

language of work or name

English

0 references

publication date

2 March 2011

1 reference

full work available at URL

13 September 2017

https://doi.org/10.1099/vir.0.030718-0

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21367983

https://www.microbiologyresearch.org/content/journal/jgv/10.1099/vir.0.030718-0?crawler=true

25 November 2024

1 reference

Crossref

DOI

https://api.crossref.org/works/10.1099/VIR.0.030718-0

Journal of General Virology

25 November 2024

published in

1 reference

13 September 2017

1 reference

13 September 2017

issue

Pt 6

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13 September 2017

page(s)

1435-1444

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Characterization of the surface proteins of influenza A (H5N1) viruses isolated from humans in 1997-1998.

13 September 2017

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A single mutation in the PB1-F2 of H5N1 (HK/97) and 1918 influenza A viruses contributes to increased virulence

25 November 2024

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Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia

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The viral polymerase mediates adaptation of an avian influenza virus to a mammalian host.

25 November 2024

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Lethality to ferrets of H5N1 influenza viruses isolated from humans and poultry in 2004.

25 November 2024

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H5N1 infection of the respiratory tract and beyond: a molecular pathology study

25 November 2024

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Emergence of multiple genotypes of H5N1 avian influenza viruses in Hong Kong SAR.

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H5N1 influenza: a protean pandemic threat

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Molecular basis for high virulence of Hong Kong H5N1 influenza A viruses

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A DNA transfection system for generation of influenza A virus from eight plasmids

25 November 2024

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Minimum molecular architectures for transcription and replication of the influenza virus

25 November 2024

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A new influenza virus virulence determinant: the NS1 protein four C-terminal residues modulate pathogenicity

25 November 2024

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A single-amino-acid substitution in the NS1 protein changes the pathogenicity of H5N1 avian influenza viruses in mice

25 November 2024

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Molecular correlates of influenza A H5N1 virus pathogenesis in mice

25 November 2024

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Selection of H5N1 influenza virus PB2 during replication in humans

25 November 2024

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Characterization of an H5N1 avian influenza virus from Taiwan

25 November 2024

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Systems-level comparison of host-responses elicited by avian H5N1 and seasonal H1N1 influenza viruses in primary human macrophages.

25 November 2024

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Genesis of a highly pathogenic and potentially pandemic H5N1 influenza virus in eastern Asia.

25 November 2024

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Virulence of H5N1 avian influenza virus enhanced by a 15-nucleotide deletion in the viral nonstructural gene

25 November 2024

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Detection of mammalian virulence determinants in highly pathogenic avian influenza H5N1 viruses: multivariate analysis of published data

25 November 2024

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Avian influenza (H5N1) viruses isolated from humans in Asia in 2004 exhibit increased virulence in mammals

25 November 2024

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Recent H5N1 avian influenza A virus increases rapidly in virulence to mice after a single passage in mice

25 November 2024

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The surface glycoproteins of H5 influenza viruses isolated from humans, chickens, and wild aquatic birds have distinguishable properties.

25 November 2024

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The effects of influenza A virus PB1-F2 protein on polymerase activity are strain specific and do not impact pathogenesis

25 November 2024

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A site on the influenza A virus NS1 protein mediates both inhibition of PKR activation and temporal regulation of viral RNA synthesis

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Influenza A virus-generated small RNAs regulate the switch from transcription to replication

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Evidence that the C-terminal PB2-binding region of the influenza A virus PB1 protein is a discrete alpha-helical domain

25 November 2024

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Pathogenesis of influenza A (H5N1) virus infection in a primate model

25 November 2024

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Influenza A virus (H5N1) infection in cats causes systemic disease with potential novel routes of virus spread within and between hosts.

25 November 2024

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The polymerase complex genes contribute to the high virulence of the human H5N1 influenza virus isolate A/Vietnam/1203/04.

25 November 2024

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Lethal H5N1 influenza viruses escape host anti-viral cytokine responses

25 November 2024

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PB2 amino acid at position 627 affects replicative efficiency, but not cell tropism, of Hong Kong H5N1 influenza A viruses in mice

25 November 2024

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Characterization of a human H5N1 influenza A virus isolated in 2003.

25 November 2024

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Evolution and adaptation of H5N1 influenza virus in avian and human hosts in Indonesia and Vietnam.

25 November 2024

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Transmission of influenza virus in a mammalian host is increased by PB2 amino acids 627K or 627E/701N.

25 November 2024

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25 November 2024

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A single amino acid in the PB2 gene of influenza A virus is a determinant of host range.

25 November 2024

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Structural insight into the essential PB1–PB2 subunit contact of the influenza virus RNA polymerase

25 November 2024

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25 November 2024

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25 November 2024

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25 November 2024

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Inefficient transmission of H5N1 influenza viruses in a ferret contact model

25 November 2024

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Pathogenesis of avian influenza A (H5N1) viruses in ferrets

25 November 2024

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https://api.crossref.org/works/10.1099/VIR.0.030718-0

25 November 2024

Identifiers

DOI

1 reference

13 September 2017

1 reference