Mitochondria Determine the Efficacy of Anticancer Agents that Interact with DNA but Not the Cytoskeleton (Q39573230)

13 September 2017

title

Mitochondria determine the efficacy of anticancer agents that interact with DNA but not the cytoskeleton (English)

1 reference

13 September 2017

Mitochondria Determine the Efficacy of Anticancer Agents that Interact with DNA but Not the Cytoskeleton (English)

1 reference

Crossref

DOI

https://api.crossref.org/works/10.1124/JPET.111.179473

27 November 2024

0 references

1 reference

Kenjirou Hara

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13 September 2017

Emiko Kasahara

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13 September 2017

Nozomi Takahashi

1 reference

13 September 2017

Masami Konishi

1 reference

13 September 2017

June Inoue

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13 September 2017

Mika Jikumaru

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13 September 2017

Shuji Kubo

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13 September 2017

Haruki Okamura

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13 September 2017

Eisuke Sato

1 reference

13 September 2017

Masayasu Inoue

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13 September 2017

language of work or name

English

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publication date

18 March 2011

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full work available at URL

13 September 2017

https://syndication.highwire.org/content/doi/10.1124/jpet.111.179473

1 reference

Crossref

DOI

https://api.crossref.org/works/10.1124/JPET.111.179473

Journal of Pharmacology and Experimental Therapeutics

27 November 2024

published in

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13 September 2017

volume

337

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13 September 2017

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13 September 2017

page(s)

838-845

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Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementation

13 September 2017

cites work

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1126/SCIENCE.2814477

Identification of strong DNA binding motifs for bleomycin

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Sequence and organization of the human mitochondrial genome

27 November 2024

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Multidrug resistance--a multiplex phenomenon

27 November 2024

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Microtubule-targeted anticancer agents and apoptosis

27 November 2024

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Cellular responses to H(2)O(2) and bleomycin-induced oxidative stress in L6C5 rat myoblasts.

27 November 2024

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L-Carnitine inhibits cisplatin-induced injury of the kidney and small intestine

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Differential mitotic responses to microtubule-stabilizing and -destabilizing drugs

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Biochemical modulation of Cisplatin mechanisms of action: enhancement of antitumor activity and circumvention of drug resistance

27 November 2024

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Targeting mitochondria for cancer therapy

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A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin

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NADPH oxidases participate to doxorubicin-induced cardiac myocyte apoptosis

27 November 2024

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The pathophysiology of mitochondrial cell death

27 November 2024

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Oxidative stress, thiol reagents, and membrane potential modulate the mitochondrial permeability transition by affecting nucleotide binding to the adenine nucleotide translocase

27 November 2024

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Mitochondrial respiratory chain-dependent generation of superoxide anion and its release into the intermembrane space

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Trastuzumab--mechanism of action and use in clinical practice

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Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species

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Roles of NADPH oxidases in cisplatin-induced reactive oxygen species generation and ototoxicity.

27 November 2024

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Alteration of the mitochondrial apoptotic pathway is key to acquired paclitaxel resistance and can be reversed by ABT-737.

27 November 2024

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Role of mitochondria in oxidative stress and ageing

27 November 2024

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Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

27 November 2024

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Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

27 November 2024

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The EGF receptor family as targets for cancer therapy

27 November 2024

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Paclitaxel promotes a caspase 8-mediated apoptosis through death effector domain association with microtubules

27 November 2024

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Effect of adriamycin on DNA, RNA, and protein synthesis in cell-free systems and intact cells

27 November 2024

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Co-ordinated over-expression of the MRP and γ-glutamylcysteine synthetase genes, but not MRD1, correlates with doxorubicin resistance in human malignant mesothelioma cell lines

27 November 2024

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Comparison of the mechanism of action of busulfan with hepsulfam, a new antileukemic agent, in the L1210 cell line

27 November 2024

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Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism

27 November 2024

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Role of reactive oxygen species and cardiolipin in the release of cytochrome c from mitochondria

27 November 2024

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Mitochondrial density determines the cellular sensitivity to cisplatin-induced cell death.

27 November 2024

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Inhibition of mitochondrial protein synthesis results in increased endothelial cell susceptibility to nitric oxide-induced apoptosis

27 November 2024

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1,25-Dihydroxyvitamin D3 enhances the susceptibility of breast cancer cells to doxorubicin-induced oxidative damage

27 November 2024

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VDAC regulation: role of cytosolic proteins and mitochondrial lipids

27 November 2024

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Reconstruction of molecular phylogeny of extant hominoids from DNA sequence data

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The expression of P-glycoprotein and multidrug resistance proteins 1 and 2 (MRP1 and MRP2) in human malignant mesothelioma.

27 November 2024

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Chemotherapy for malignant pleural mesothelioma: past results and recent developments

27 November 2024

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Paclitaxel-induced apoptosis in BJAB cells proceeds via a death receptor-independent, caspases-3/-8-driven mitochondrial amplification loop

27 November 2024

1 reference

https://api.crossref.org/works/10.1124/JPET.111.179473

Gold(III) Porphyrin 1a Induced Apoptosis by Mitochondrial Death Pathways Related to Reactive Oxygen Species

27 November 2024

1 reference

https://api.crossref.org/works/10.1124/JPET.111.179473

Cytochrome c maintains mitochondrial transmembrane potential and ATP generation after outer mitochondrial membrane permeabilization during the apoptotic process

27 November 2024

1 reference

https://api.crossref.org/works/10.1124/JPET.111.179473

Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3.

27 November 2024

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https://api.crossref.org/works/10.1124/JPET.111.179473

Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress

27 November 2024

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Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

27 November 2024

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27 November 2024

Identifiers

DOI

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release_u3yngkj23rg5bmxydkdipq4r4q

13 September 2017

Fatcat ID

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