Mutations in nonconserved domains of Ty3 integrase affect multiple stages of the Ty3 life cycle (Q39548812)

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7 December 2019

title

Mutations in nonconserved domains of Ty3 integrase affect multiple stages of the Ty3 life cycle (English)

1 reference

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7 December 2019

M H Nymark-McMahon

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7 December 2019

S B Sandmeyer

series ordinal

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7 December 2019

language of work or name

English

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publication date

1 January 1999

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7 December 2019

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7 December 2019

volume

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7 December 2019

issue

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7 December 2019

page(s)

453-465

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The yeast Ty3 retrotransposon contains a 5'-3' bipartite primer-binding site and encodes nucleocapsid protein NCp9 functionally homologous to HIV-1 NCp7

7 December 2019

cites work

1 reference

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Invading the Yeast Nucleus: a Nuclear Localization Signal at the C Terminus of Ty1 Integrase Is Required for Transposition In Vivo

13 September 2017

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A Ty1 Integrase Nuclear Localization Signal Required for Retrotransposition

13 September 2017

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A large nucleoprotein assembly at the ends of the viral DNA mediates retroviral DNA integration

13 September 2017

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Critical contacts between HIV-1 integrase and viral DNA identified by structure-based analysis and photo-crosslinking

13 September 2017

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HIV-1 infection of nondividing cells through the recognition of integrase by the importin/karyopherin pathway

13 September 2017

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13 September 2017

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13 September 2017

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13 September 2017

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13 September 2017

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Domains of the integrase protein of human immunodeficiency virus type 1 responsible for polynucleotidyl transfer and zinc binding

13 September 2017

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Role of the His-Cys finger of Moloney murine leukemia virus integrase protein in integration and disintegration

13 September 2017

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Characterization of a DNA binding domain in the C-terminus of HIV-1 integrase by deletion mutagenesis

13 September 2017

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Identification of discrete functional domains of HIV-1 integrase and their organization within an active multimeric complex

13 September 2017

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A proposed superfamily of transposase genes: transposon-like elements in ciliated protozoa and a common "D35E" motif

13 September 2017

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Genetic analysis of homomeric interactions of human immunodeficiency virus type 1 integrase using the yeast two-hybrid system

13 September 2017

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13 September 2017

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The core and carboxyl-terminal domains of the integrase protein of human immunodeficiency virus type 1 each contribute to nonspecific DNA binding.

13 September 2017

1 reference

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Human immunodeficiency virus type 1 integrase: effects of mutations on viral ability to integrate, direct viral gene expression from unintegrated viral DNA templates, and sustain viral propagation in primary cells

13 September 2017

1 reference

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Transposition of the yeast retroviruslike element Ty3 is dependent on the cell cycle

13 September 2017

1 reference

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13 September 2017

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Identification of residues in the Mu transposase essential for catalysis

13 September 2017

1 reference

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Characterization of the human spuma retrovirus integrase by site-directed mutagenesis, by complementation analysis, and by swapping the zinc finger domain of HIV-1.

13 September 2017

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Linker insertion mutations in the human immunodeficiency virus type 1 gag gene: effects on virion particle assembly, release, and infectivity.

13 September 2017

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Integration is required for productive infection of monocyte-derived macrophages by human immunodeficiency virus type 1.

13 September 2017

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Ty3 transposes in mating populations of yeast: a novel transposition assay for Ty3

13 September 2017

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Association of integrase, matrix, and reverse transcriptase antigens of human immunodeficiency virus type 1 with viral nucleic acids following acute infection

13 September 2017

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Mapping domains of retroviral integrase responsible for viral DNA specificity and target site selection by analysis of chimeras between human immunodeficiency virus type 1 and visna virus integrases

13 September 2017

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13 September 2017

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13 September 2017

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13 September 2017

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Amino Acid Sequence Analysis of Reverse Transcriptase Subunits from Avian Myeloblastosis Virus

13 September 2017

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13 September 2017

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13 September 2017

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A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coli

13 September 2017

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Ty3, a yeast retrotransposon associated with tRNA genes, has homology to animal retroviruses

13 September 2017

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The avian retroviral integration protein cleaves the terminal sequences of linear viral DNA at the in vivo sites of integration

13 September 2017

1 reference

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Retroviral integration: structure of the initial covalent product and its precursor, and a role for the viral IN protein

13 September 2017

1 reference

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Computer analysis of retroviral pol genes: assignment of enzymatic functions to specific sequences and homologies with nonviral enzymes

13 September 2017

1 reference

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Characterization of a transpositionally active Ty3 element and identification of the Ty3 integrase protein

13 September 2017

1 reference

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A systematic mutational analysis of hormone-binding determinants in the human growth hormone receptor

13 September 2017

1 reference

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DNA binding properties of the integrase proteins of human immunodeficiency viruses types 1 and 2

13 September 2017

1 reference

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Retroviral integrase domains: DNA binding and the recognition of LTR sequences

13 September 2017

1 reference

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Defining nucleic acid-binding properties of avian retrovirus integrase by deletion analysis

13 September 2017

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A covalent complex between retroviral integrase and nicked substrate DNA

13 September 2017

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The N-terminal region of HIV-1 integrase is required for integration activity, but not for DNA-binding

13 September 2017

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Localization of DNA binding activity of HIV-1 integrase to the C-terminal half of the protein

13 September 2017

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Mutational analysis of the integrase protein of human immunodeficiency virus type 2

13 September 2017

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Identification of conserved amino acid residues critical for human immunodeficiency virus type 1 integrase function in vitro

13 September 2017

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Ty3 GAG3 and POL3 genes encode the components of intracellular particles

13 September 2017

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Residues critical for retroviral integrative recombination in a region that is highly conserved among retroviral/retrotransposon integrases and bacterial insertion sequence transposases

13 September 2017

1 reference

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

13 September 2017

1 reference

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Virus-coded origin of a 32,000-dalton protein from avian retrovirus cores: structural relatedness of p32 and the beta polypeptide of the avian retrovirus DNA polymerase

13 September 2017

1 reference

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3'-end processing and kinetics of 5'-end joining during retroviral integration in vivo.

13 September 2017

1 reference

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Ty3 integrase mutants defective in reverse transcription or 3'-end processing of extrachromosomal Ty3 DNA.

14 September 2017

1 reference

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Conserved residues Pro-109 and Asp-116 are required for interaction of the human immunodeficiency virus type 1 integrase protein with its viral DNA substrate.

14 September 2017

1 reference

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Rous sarcoma virus integrase protein: mapping functions for catalysis and substrate binding

14 September 2017

1 reference

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Human immunodeficiency virus type 1 integrase: effect on viral replication of mutations at highly conserved residues.

14 September 2017

1 reference

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Identification and characterization of a temperature-sensitive mutant of human immunodeficiency virus type 1 by alanine scanning mutagenesis of the integrase gene

14 September 2017

1 reference

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Characterization of the minimal DNA-binding domain of the HIV integrase protein

14 September 2017

1 reference

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Proteolytic processing of Ty3 proteins is required for transposition

14 September 2017

1 reference

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Requirement of active human immunodeficiency virus type 1 integrase enzyme for productive infection of human T-lymphoid cells

14 September 2017

1 reference

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The Core Domain of HIV-1 Integrase Recognizes Key Features of Its DNA Substrates

14 September 2017

1 reference

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Structural characterization of the avian retrovirus reverse transcriptase and endonuclease domains

25 September 2017

1 reference

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The IN protein of Moloney murine leukemia virus processes the viral DNA ends and accomplishes their integration in vitro

17 June 2018

1 reference

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Rational scanning mutagenesis of a protein kinase identifies functional regions involved in catalysis and substrate interactions

17 June 2018

1 reference

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17 June 2018

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Reversal of Integration and DNA Splicing Mediated by Integrase of Human Immunodeficiency Virus

17 June 2018

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Identification of amino acid residues critical for endonuclease and integration activities of HIV-1 IN protein in vitro

17 June 2018

1 reference

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Ty3 integrates within the region of RNA polymerase III transcription initiation

17 June 2018

1 reference

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Central core domain of retroviral integrase is responsible for target site selection

17 June 2018

1 reference

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Site-directed mutagenesis of HIV-1 integrase demonstrates differential effects on integrase functions in vitro

21 August 2018

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Tn7 transposition: target DNA recognition is mediated by multiple Tn7-encoded proteins in a purified in vitro system

21 August 2018

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Tn552, a novel transposable element from Staphylococcus aureus

21 August 2018

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An essential interaction between distinct domains of HIV-1 integrase mediates assembly of the active multimer

21 August 2018

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12 December 2020

A soluble active mutant of HIV-1 integrase: involvement of both the core and carboxyl-terminal domains in multimerization

1 reference

12 December 2020

Structure of the termini of DNA intermediates in the integration of retroviral DNA: dependence on IN function and terminal DNA sequence

1 reference

12 December 2020

HIV-1 DNA integration: Mechanism of viral DNA cleavage and DNA strand transfer

1 reference

12 December 2020

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9847351%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

PubMed publication ID

9847351

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9847351%20AND%20SRC:MED&resulttype=core&format=json