Effects of cell culture conditions on antibody N‐linked glycosylation—what affects high mannose 5 glycoform (Q39545373)

12 September 2017

title

Effects of cell culture conditions on antibody N-linked glycosylation--what affects high mannose 5 glycoform (English)

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12 September 2017

Effects of cell culture conditions on antibody N‐linked glycosylation—what affects high mannose 5 glycoform (English)

1 reference

1 December 2024

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21557201

1 December 2024

Efren Pacis

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12 September 2017

Marcella Yu

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12 September 2017

Jennifer Autsen

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12 September 2017

Robert Bayer

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12 September 2017

Feng Li

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12 September 2017

language of work or name

English

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21557201

1 December 2024

publication date

24 May 2011

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full work available at URL

12 September 2017

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fbit.23200

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https://onlinelibrary.wiley.com/doi/pdf/10.1002/bit.23200

1 December 2024

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Biotechnology and Bioengineering

1 December 2024

published in

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12 September 2017

volume

108

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12 September 2017

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12 September 2017

page(s)

2348-2358

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Effect of culture temperature on erythropoietin production and glycosylation in a perfusion culture of recombinant CHO cells.

12 September 2017

cites work

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Multiple cell culture factors can affect the glycosylation of Asn-184 in CHO-produced tissue-type plasminogen activator

21 January 2018

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The effect of Fc glycan forms on human IgG2 antibody clearance in humans

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Gene-expression profiles for five key glycosylation genes for galactose-fed CHO cells expressing recombinant IL-4/13 cytokine trap

21 January 2018

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Amino acid and manganese supplementation modulates the glycosylation state of erythropoietin in a CHO culture system.

21 January 2018

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Ammonium alters N-glycan structures of recombinant TNFR-IgG: degradative versus biosynthetic mechanisms

21 January 2018

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21 January 2018

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X-ray crystal structures of rabbit N-acetylglucosaminyltransferase I (GnT I) in complex with donor substrate analogues

21 January 2018

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Mechanisms of unintended amino acid sequence changes in recombinant monoclonal antibodies expressed in Chinese Hamster Ovary (CHO) cells

21 January 2018

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21 January 2018

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Metabolic control of recombinant monoclonal antibody N-glycosylation in GS-NS0 cells

21 January 2018

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N-glycans of recombinant human interferon-gamma change during batch culture of chinese hamster ovary cells.

21 January 2018

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Glycosylation of recombinant antibody therapeutics

21 January 2018

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Comparison of biological activity among nonfucosylated therapeutic IgG1 antibodies with three different N-linked Fc oligosaccharides: the high-mannose, hybrid, and complex types

21 January 2018

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Depletion of manganese within the secretory pathway inhibits O-linked glycosylation in mammalian cells

21 January 2018

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Assembly of asparagine-linked oligosaccharides

21 January 2018

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Comparability assessments of process and product changes made during development of two different monoclonal antibodies

21 January 2018

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Carbohydrate analysis of a chimeric recombinant monoclonal antibody by capillary electrophoresis with laser-induced fluorescence detection

21 January 2018

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Non-fucosylated therapeutic antibodies: the next generation of therapeutic antibodies

21 January 2018

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Characterization of a recombinant antibody produced in the course of a high yield fed-batch process

21 January 2018

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Hyperosmotic stress and elevated pCO2 alter monoclonal antibody charge distribution and monosaccharide content

21 January 2018

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The importance of ammonia in mammalian cell culture

21 January 2018

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Lack of fucose on human IgG1 N-linked oligosaccharide improves binding to human Fcgamma RIII and antibody-dependent cellular toxicity

21 January 2018

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X-ray crystal structure of rabbit N-acetylglucosaminyltransferase I: catalytic mechanism and a new protein superfamily

21 January 2018

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Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity

21 January 2018

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N-linked glycosylation is an important parameter for optimal selection of cell lines producing biopharmaceutical human IgG.

21 January 2018

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Post-translational modifications in the context of therapeutic proteins

21 January 2018

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In vivo trafficking and catabolism of IgG1 antibodies with Fc associated carbohydrates of differing structure

21 January 2018

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Specificity and mechanism of metal ion activation in UDP-galactose:beta -galactoside-alpha -1,3-galactosyltransferase

21 January 2018

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Development of a simple and rapid method for producing non-fucosylated oligomannose containing antibodies with increased effector function

21 January 2018

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Culture pH affects expression rates and glycosylation of recombinant mouse placental lactogen proteins by Chinese hamster ovary (CHO) cells

21 January 2018

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Bicarbonate concentration and osmolality are key determinants in the inhibition of CHO cell polysialylation under elevated pCO2 or pH

1 December 2024

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1 December 2024

Identifiers

DOI

10.1002/BIT.23200

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12 September 2017

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