Charge heterogeneity: Basic antibody charge variants with increased binding to Fc receptors (Q39454978)

12 September 2017

Charge heterogeneity: Basic antibody charge variants with increased binding to Fc receptors (English)

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12 September 2017

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0 references

Beate Hintersteiner

1 reference

12 September 2017

Nico Lingg

1 reference

12 September 2017

Peiqing Zhang

1 reference

12 September 2017

Susanto Woen

1 reference

12 September 2017

Kong Meng Hoi

1 reference

12 September 2017

Stefan Stranner

1 reference

12 September 2017

Susanne Wiederkum

1 reference

12 September 2017

Oliver Mutschlechner

1 reference

12 September 2017

Manfred Schuster

1 reference

12 September 2017

Hans Loibner

1 reference

12 September 2017

25 August 2016

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12 September 2017

Monoclonal Antibodies

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12 September 2017

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12 September 2017

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12 September 2017

1548-1560

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Creative Commons Attribution-NonCommercial 3.0 Unported

12 September 2017

start time

25 August 2016

1 reference

April 2022 Public Data File from Crossref

copyrighted

1 reference

April 2022 Public Data File from Crossref

cites work

Pharmacokinetics and pharmacodynamics of ch14.18/CHO in relapsed/refractory high-risk neuroblastoma patients treated by long-term infusion in combination with IL-2

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The neonatal Fc receptor, FcRn, as a target for drug delivery and therapy

12 September 2017

1 reference

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In vitro and in vivo modifications of recombinant and human IgG antibodies

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098448

IgG subclasses and allotypes: from structure to effector functions

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098448

Therapeutic monoclonal antibodies and consistent ends: terminal heterogeneity, detection, and impact on quality

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098448

Contribution of Human FcγRs to Disease with Evidence from Human Polymorphisms and Transgenic Animal Studies

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098448

IgG-effector functions: "the good, the bad and the ugly".

12 September 2017

1 reference

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The function of Fcγ receptors in dendritic cells and macrophages

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098448

Engineering anti-GD2 monoclonal antibodies for cancer immunotherapy

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098448

Ch14.18 antibody produced in CHO cells in relapsed or refractory Stage 4 neuroblastoma patients: a SIOPEN Phase 1 study.

12 September 2017

1 reference

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Targeted immunotherapy for high-risk neuroblastoma--the role of monoclonal antibodies

12 September 2017

1 reference

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Glycoproteomic analysis of antibodies

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098448

Minimizing immunogenicity of biopharmaceuticals by controlling critical quality attributes of proteins

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098448

The sweet tooth of biopharmaceuticals: importance of recombinant protein glycosylation analysis.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098448

Chromatographic analysis of the acidic and basic species of recombinant monoclonal antibodies

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098448

Disulfide bond structures of IgG molecules: structural variations, chemical modifications and possible impacts to stability and biological function

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098448

Erythropoietin Produced in a Human Cell Line (Dynepo) Has Significant Differences in Glycosylation Compared with Erythropoietins Produced in CHO Cell Lines

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098448

Assessing monoclonal antibody product quality attribute criticality through clinical studies

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098448

Post-translational modifications differentially affect IgG1 conformation and receptor binding.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098448

Trends in glycosylation, glycoanalysis and glycoengineering of therapeutic antibodies and Fc-fusion proteins

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098448

Overview of Biacore systems and their applications

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098448

Heterogeneity of monoclonal antibodies

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098448

Structural characterization of N-linked oligosaccharides on monoclonal antibody cetuximab by the combination of orthogonal matrix-assisted laser desorption/ionization hybrid quadrupole-quadrupole time-of-flight tandem mass spectrometry and sequentia

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098448

Comparison of biological activity among nonfucosylated therapeutic IgG1 antibodies with three different N-linked Fc oligosaccharides: the high-mannose, hybrid, and complex types

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098448

Control of recombinant monoclonal antibody effector functions by Fc N-glycan remodeling in vitro

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098448

Oxidation of methionine in proteins: roles in antioxidant defense and cellular regulation

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098448

Anti-neuroblastoma effect of ch14.18 antibody produced in CHO cells is mediated by NK-cells in mice.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098448

A summary of the measured pK values of the ionizable groups in folded proteins

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098448

Pharmacokinetics of the chimeric anti-GD2 antibody, ch14.18, in children with high-risk neuroblastoma.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098448

IRES-mediated Tricistronic vectors for enhancing generation of high monoclonal antibody expressing CHO cell lines.

21 August 2018

1 reference

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Identification of isomerization and racemization of aspartate in the Asp-Asp motifs of a therapeutic protein

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098448

In vivo glyco-engineered antibody with improved lytic potential produced by an innovative non-mammalian expression system

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098448

Complement and cellular cytotoxicity in antibody therapy of cancer

21 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1080%2F19420862.2016.1225642

Very alkaline immobilized pH gradients for two-dimensional electrophoresis of ribosomal and nuclear proteins

21 January 2018

1 reference

12 December 2020

Effect of posttranslational modifications on the thermal stability of a recombinant monoclonal antibody

1 reference

12 December 2020

Highly linear pH gradients for analyzing monoclonal antibody charge heterogeneity in the alkaline range

1 reference

12 December 2020

Advances in the assessment and control of the effector functions of therapeutic antibodies

1 reference

12 December 2020

Highly linear pH gradients for analyzing monoclonal antibody charge heterogeneity in the alkaline range: Validation of the method parameters

1 reference

12 December 2020

10.1080/19420862.2016.1225642

Identifiers

DOI

1 reference

12 September 2017

1 reference

12 September 2017

PubMed publication ID

27559765

1 reference