Dual signaling role of the protein tyrosine phosphatase SHP-2 in regulating expression of acute-phase plasma proteins by interleukin-6 cytokine receptors in hepatic cells. (Q39446572)

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English	Dual signaling role of the protein tyrosine phosphatase SHP-2 in regulating expression of acute-phase plasma proteins by interleukin-6 cytokine receptors in hepatic cells.	scientific article

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10 December 2019

Dual signaling role of the protein tyrosine phosphatase SHP-2 in regulating expression of acute-phase plasma proteins by interleukin-6 cytokine receptors in hepatic cells (English)

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10 December 2019

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10 December 2019

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H Baumann

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1 August 1999

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10 December 2019

Molecular and Cellular Biology

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10 December 2019

19

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10 December 2019

5326-5338

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10 December 2019

Transcriptional activation of the p21(WAF1,CIP1,SDI1) gene by interleukin-6 type cytokines. A prerequisite for their pro-differentiating and anti-apoptotic effects on human osteoblastic cells

1 reference

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12 September 2017

Requirement of ErbB2 for signalling by interleukin-6 in prostate carcinoma cells

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12 September 2017

Stat3 activation is required for cellular transformation by v-src

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12 September 2017

Roles of the complex formation of SHPS-1 with SHP-2 in insulin-stimulated mitogen-activated protein kinase activation

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12 September 2017

Crystal Structure of the Tyrosine Phosphatase SHP-2

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12 September 2017

Protein tyrosine phosphatase 2 (SHP-2) moderates signaling by gp130 but is not required for the induction of acute-phase plasma protein genes in hepatic cells

1 reference

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12 September 2017

The Caenorhabditis elegans SH2 domain-containing protein tyrosine phosphatase PTP-2 participates in signal transduction during oogenesis and vulval development

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12 September 2017

The Protein-tyrosine Phosphatase SHP-2 Associates with Tyrosine-phosphorylated Adhesion Molecule PECAM-1 (CD31)

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12 September 2017

The protein tyrosine phosphatase SHP-2 negatively regulates ciliary neurotrophic factor induction of gene expression

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12 September 2017

Structure and function of a new STAT-induced STAT inhibitor

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12 September 2017

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Mitogen-activated and cyclin-dependent protein kinases selectively and differentially modulate transcriptional enhancement by the glucocorticoid receptor

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Box 3-independent signaling mechanisms are involved in leukemia inhibitory factor receptor alpha- and gp130-mediated stimulation of mitogen-activated protein kinase. Evidence for participation of multiple signaling pathways which converge at Ras

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Abnormal mesoderm patterning in mouse embryos mutant for the SH2 tyrosine phosphatase Shp-2.

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12 September 2017

Protein tyrosine phosphatases in signal transduction.

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12 September 2017

Molecular characterization of specific interactions between SHP-2 phosphatase and JAK tyrosine kinases

1 reference

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12 September 2017

Direct association with and dephosphorylation of Jak2 kinase by the SH2-domain-containing protein tyrosine phosphatase SHP-1

1 reference

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12 September 2017

A novel membrane glycoprotein, SHPS-1, that binds the SH2-domain-containing protein tyrosine phosphatase SHP-2 in response to mitogens and cell adhesion

1 reference

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12 September 2017

Activation of protein-tyrosine phosphatase SH-PTP2 by a tyrosine-based activation motif of a novel brain molecule

1 reference

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12 September 2017

Regulation of transcription by MAP kinase cascades

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12 September 2017

Dimerization of the extracellular domain of granuloycte-colony stimulating factor receptor by ligand binding: a monovalent ligand induces 2:2 complexes

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12 September 2017

The SH2 domain-containing tyrosine phosphatase PTP1D is required for interferon alpha/beta-induced gene expression

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12 September 2017

Differential activation of acute phase response factor/Stat3 and Stat1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. II. Src homology SH2 domains define the specificity of stat factor activation

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12 September 2017

Two separate signal transducer and activator of transcription proteins regulate transcription of the serine proteinase inhibitor-3 gene in hepatic cells

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12 September 2017

STAT3 activation is a critical step in gp130-mediated terminal differentiation and growth arrest of a myeloid cell line

1 reference

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12 September 2017

Dominant negative stat3 mutant inhibits interleukin-6-induced Jak-STAT signal transduction

1 reference

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12 September 2017

STAT3 participates in transcriptional activation of the C-reactive protein gene by interleukin-6.

1 reference

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12 September 2017

Identification of the interleukin-6/oncostatin M response element in the rat tissue inhibitor of metalloproteinases-1 (TIMP-1) promoter

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12 September 2017

Transcription factors Stat3 and Stat5b are present in rat liver nuclei late in an acute phase response and bind interleukin-6 response elements

1 reference

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12 September 2017

The insulin receptor substrate 1 associates with the SH2-containing phosphotyrosine phosphatase Syp

1 reference

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12 September 2017

Activation of activating protein 1 during hepatic acute phase response

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12 September 2017

Phosphorylation at threonine-235 by a ras-dependent mitogen-activated protein kinase cascade is essential for transcription factor NF-IL6

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12 September 2017

Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components

1 reference

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12 September 2017

Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130.

1 reference

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12 September 2017

A new function for a phosphotyrosine phosphatase: linking GRB2-Sos to a receptor tyrosine kinase

1 reference

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12 September 2017

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

1 reference

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12 September 2017

Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals

1 reference

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12 September 2017

Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors

1 reference

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12 September 2017

Separate signaling mechanisms are involved in the control of STAT protein activation and gene regulation via the interleukin 6 response element by the box 3 motif of gp130

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84376

12 September 2017

Requirement of serine phosphorylation for formation of STAT-promoter complexes

1 reference

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12 September 2017

The 64-kDa protein that associates with the platelet-derived growth factor receptor beta subunit via Tyr-1009 is the SH2-containing phosphotyrosine phosphatase Syp

1 reference

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12 September 2017

Association of SH2 domain protein tyrosine phosphatases with the epidermal growth factor receptor in human tumor cells. Phosphatidic acid activates receptor dephosphorylation by PTP1C

1 reference

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12 September 2017

A synthetic inhibitor of the mitogen-activated protein kinase cascade

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12 September 2017

Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation

1 reference

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12 September 2017

Interleukin (IL)-3 and granulocyte/macrophage colony-stimulating factor, but not IL-4, induce tyrosine phosphorylation, activation, and association of SHPTP2 with Grb2 and phosphatidylinositol 3'-kinase

1 reference

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12 September 2017

Adapter function of protein-tyrosine phosphatase 1D in insulin receptor/insulin receptor substrate-1 interaction

1 reference

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12 September 2017

Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen

1 reference

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12 September 2017

Stimulation of hepatic acute phase response by cytokines and glucocorticoids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84376

12 September 2017

Regulation of major acute-phase plasma proteins by hepatocyte-stimulating factors of human squamous carcinoma cells

1 reference

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12 September 2017

Cellular and molecular biology of hepatocyte growth, regeneration and gene expression.

1 reference

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12 September 2017

Shp-2 has a positive regulatory role in ES cell differentiation and proliferation

1 reference

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25 September 2017

Coordinate regulation of STAT signaling and c-fos expression by the tyrosine phosphatase SHP-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84376

25 September 2017

Differentiation and growth arrest signals are generated through the cytoplasmic region of gp130 that is essential for Stat3 activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84376

25 September 2017

Interleukin-2 induces tyrosine phosphorylation of SHP-2 through IL-2 receptor beta chain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84376

25 September 2017

Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis.

1 reference

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25 September 2017

Expression of dominant negative mutant SHPTP2 attenuates phosphatidylinositol 3'-kinase activity via modulation of phosphorylation of insulin receptor substrate-1.

1 reference

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25 September 2017

Involvement of Janus kinases, p52shc, Raf-1, and MEK-1 in the IL-6-induced mitogen-activated protein kinase cascade of a growth-responsive B cell line.

1 reference

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25 September 2017

Receptors for interleukin-3 (IL-3) and growth hormone mediate an IL-6-type transcriptional induction in the presence of JAK2 or STAT3

1 reference

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25 September 2017

Signaling mechanisms through gp130: a model of the cytokine system

1 reference

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17 June 2018

Glucocorticoids Stimulate p21 Gene Expression by Targeting Multiple Transcriptional Elements within a Steroid Responsive Region of the p21 Promoter in Rat Hepatoma Cells

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17 June 2018

SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases

1 reference

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17 June 2018

Expression of catalytically inactive Syp phosphatase in 3T3 cells blocks stimulation of mitogen-activated protein kinase by insulin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84376

17 June 2018

Syp associates with gp130 and Janus kinase 2 in response to interleukin-11 in 3T3-L1 mouse preadipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84376

17 June 2018

The murine interleukin-4 receptor: molecular cloning and characterization of secreted and membrane bound forms

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17 June 2018

Gene expression in regenerating and acute-phase rat liver

1 reference

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17 June 2018

Influence of interleukin-6 (IL-6) dimerization on formation of the high affinity hexameric IL-6.receptor complex.

1 reference

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21 August 2018

Daughter of sevenless is a substrate of the phosphotyrosine phosphatase Corkscrew and functions during sevenless signaling

1 reference

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21 August 2018

Syp (SH-PTP2) is a positive mediator of growth factor-stimulated mitogenic signal transduction

1 reference

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21 August 2018

Interleukin-6 and ciliary neurotrophic factor trigger janus kinase activation and early gene response in rat hepatocytes

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https://pubmed.ncbi.nlm.nih.gov/10409724

12 December 2020

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The mitogen-activated protein kinase and JAK-STAT signaling pathways are required for an oncostatin M-responsive element-mediated activation of matrix metalloproteinase 1 gene expression

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https://pubmed.ncbi.nlm.nih.gov/10409724

12 December 2020

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The carboxyl-terminal region of STAT3 controls gene induction by the mouse haptoglobin promoter

1 reference

https://pubmed.ncbi.nlm.nih.gov/10409724

12 December 2020

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Insulin modulates STAT3 protein activation and gene transcription in hepatic cells

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12 December 2020

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The AP-1 sequence is necessary but not sufficient for phorbol induction of collagenase in fibroblasts

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Oncostatin M Stimulates c-Fos to Bind a Transcriptionally Responsive AP-1 Element within the Tissue Inhibitor of Metalloproteinase-1 Promoter

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12 December 2020

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Modulation of hepatic acute phase gene expression by epidermal growth factor and Src protein tyrosine kinases in murine and human hepatic cells

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Identifiers

10.1128/MCB.19.8.5326

1 reference

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10 December 2019

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10 December 2019

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10 December 2019

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