Molecular mechanisms underlying Th1-like Treg generation and function. (Q39380502)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28624966%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

review article

1 reference

title

Molecular mechanisms underlying Th1-like Treg generation and function (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28624966%20AND%20SRC:MED&resulttype=core&format=json

Margarita Domínguez-Villar

23 March 2020

author

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28624966%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Alexandra Kitz

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28624966%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

publication date

17 June 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28624966%20AND%20SRC:MED&resulttype=core&format=json

Cellular and Molecular Life Sciences

23 March 2020

published in

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23 March 2020

volume

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23 March 2020

issue

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23 March 2020

page(s)

4059-4075

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28624966%20AND%20SRC:MED&resulttype=core&format=json

Regulatory B cells: origin, phenotype, and function.

23 March 2020

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Regulatory T cell reprogramming toward a Th2-cell-like lineage impairs oral tolerance and promotes food allergy

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Identification of T helper type 1–like, Foxp3+ regulatory T cells in human autoimmune disease

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Plasticity of human regulatory T cells in healthy subjects and patients with type 1 diabetes.

21 January 2018

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Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection

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IFN-γ- and IL-10-expressing virus epitope-specific Foxp3(+) T reg cells in the central nervous system during encephalomyelitis

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Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation.

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T-bet binding to newly identified target gene promoters is cell type-independent but results in variable context-dependent functional effects

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T-bet(+) Treg cells undergo abortive Th1 cell differentiation due to impaired expression of IL-12 receptor β2

21 January 2018

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Co-expression of TNFR2 and CD25 identifies more of the functional CD4+FOXP3+ regulatory T cells in human peripheral blood.

21 January 2018

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Cutting edge: expression of TNFR2 defines a maximally suppressive subset of mouse CD4+CD25+FoxP3+ T regulatory cells: applicability to tumor-infiltrating T regulatory cells.

21 January 2018

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TNF optimally activatives regulatory T cells by inducing TNF receptor superfamily members TNFR2, 4-1BB and OX40

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TNF downmodulates the function of human CD4+CD25hi T-regulatory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Anti-TNF-alpha therapy induces a distinct regulatory T cell population in patients with rheumatoid arthritis via TGF-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Differential control of Helios(+/-) Treg development by monocyte subsets through disparate inflammatory cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Function of miR-146a in controlling Treg cell-mediated regulation of Th1 responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Transcriptome profiling of human FoxP3+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

AKT isoforms modulate Th1-like Treg generation and function in human autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

The Akt kinases: isoform specificity in metabolism and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Functional cooperation of the interleukin-2 receptor beta chain and Jak1 in phosphatidylinositol 3-kinase recruitment and phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Heterotrimeric G-protein betagamma-dimers in growth and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

mTOR complex 2 targets Akt for proteasomal degradation via phosphorylation at the hydrophobic motif.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Differential effects of protein kinase B/Akt isoforms on glucose homeostasis and islet mass.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Akt isoforms in vascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Foxo transcription factors control regulatory T cell development and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Foxo proteins cooperatively control the differentiation of Foxp3+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Molecular pathways: PI3K pathway phosphatases as biomarkers for cancer prognosis and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

PI3 kinase signalling blocks Foxp3 expression by sequestering Foxo factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Control of PI(3) kinase in Treg cells maintains homeostasis and lineage stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Opposing functions of Akt isoforms in lung tumor initiation and progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Suppression of inflammatory responses during myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis is regulated by AKT3 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Production of Proinflammatory Cytokines by Monocytes in Liver-Transplanted Recipients with De Novo Autoimmune Hepatitis Is Enhanced and Induces TH1-like Regulatory T Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

TLR4 regulates IFN-γ and IL-17 production by both thymic and induced Foxp3+ Tregs during intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Interleukin-12 converts Foxp3+ regulatory T cells to interferon-γ-producing Foxp3+ T cells that inhibit colitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Helios Should Not Be Cited as a Marker of Human Thymus-Derived Tregs. Commentary: Helios(+) and Helios(-) Cells Coexist within the Natural FOXP3(+) T Regulatory Cell Subset in Humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Helios+ and Helios- cells coexist within the natural FOXP3+ T regulatory cell subset in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Differences in Expression Level of Helios and Neuropilin-1 Do Not Distinguish Thymus-Derived from Extrathymically-Induced CD4+Foxp3+ Regulatory T Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Th1-Like ICOS+ Foxp3+ Treg Cells Preferentially Express CXCR3 and Home to β-Islets during Pre-Diabetes in BDC2.5 NOD Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

The cytokines interleukin 27 and interferon-γ promote distinct Treg cell populations required to limit infection-induced pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

IFN-γ production by allogeneic Foxp3+ regulatory T cells is essential for preventing experimental graft-versus-host disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Science gone translational: the OX40 agonist story

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Therapeutic uses of anti-PD-1 and anti-PD-L1 antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Ipilimumab-dependent cell-mediated cytotoxicity of regulatory T cells ex vivo by nonclassical monocytes in melanoma patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Umbilical cord blood-derived T regulatory cells to prevent GVHD: kinetics, toxicity profile, and clinical effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Clinical application of expanded CD4+25+ cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Type 1 diabetes immunotherapy using polyclonal regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Alloantigen-specific regulatory T cells generated with a chimeric antigen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Expression of Helios in Peripherally Induced Foxp3+ Regulatory T Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Treg cells suppress osteoclast formation: a new link between the immune system and bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Altered activation of AKT is required for the suppressive function of human CD4+CD25+ T regulatory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

CD4+CD25+ regulatory T cells modulate human dendritic cell chemokines via multiple mechanisms: comment on the article by Kolar et al

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Foxp3-dependent programme of regulatory T-cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2569-Y

Functional CD4+CD25high regulatory T cells are enriched in the colonic mucosa of patients with active ulcerative colitis and increase with disease activity

21 January 2018

1 reference

12 December 2020

T cell receptor stimulation-induced epigenetic changes and Foxp3 expression are independent and complementary events required for Treg cell development

1 reference

12 December 2020

CD4+CD25high regulatory cells in human peripheral blood

1 reference

12 December 2020

Epigenetic control of FOXP3 expression: the key to a stable regulatory T-cell lineage?

1 reference

12 December 2020

Therapy of type 1 diabetes with CD4(+)CD25(high)CD127-regulatory T cells prolongs survival of pancreatic islets - results of one year follow-up

1 reference

12 December 2020

Cutting edge: direct suppression of B cells by CD4+ CD25+ regulatory T cells

1 reference

12 December 2020

PKB/Akt: a key mediator of cell proliferation, survival and insulin responses?

1 reference

12 December 2020

Generation of CD4(+)CD25(+) regulatory T cells from autoreactive T cells simultaneously with their negative selection in the thymus and from nonautoreactive T cells by endogenous TCR expression

1 reference

12 December 2020

Memory CD4+ T cells are suppressed by CD8+ regulatory T cells in vitro and in vivo

1 reference

12 December 2020

Origin of regulatory T cells with known specificity for antigen

1 reference

12 December 2020

Transcriptional partners in regulatory T cells: Foxp3, Runx and NFAT

1 reference

12 December 2020

Impaired Fas response and autoimmunity in Pten+/- mice

1 reference

12 December 2020

Homeostasis of peripheral CD4+ T cells: IL-2R alpha and IL-2 shape a population of regulatory cells that controls CD4+ T cell numbers

1 reference

12 December 2020

Upregulation of Foxp3 expression in mouse and human Treg is IL-2/STAT5 dependent: implications for the NOD STAT5B mutation in diabetes pathogenesis

1 reference

12 December 2020

Recognition of the peripheral self by naturally arising CD25+ CD4+ T cell receptors

1 reference

12 December 2020

Transcriptional regulation of adipogenesis

1 reference

12 December 2020

High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice

1 reference

12 December 2020

Foxp3 Transcription-Factor-Dependent and -Independent Regulation of the Regulatory T Cell Transcriptional Signature

1 reference

12 December 2020

Origin and T cell receptor diversity of Foxp3+CD4+CD25+ T cells

1 reference

12 December 2020

Regulation of D-3 phosphoinositides during T cell activation via the T cell antigen receptor/CD3 complex and CD2 antigens

1 reference

12 December 2020

Foxp3+ regulatory T cells of psoriasis patients easily differentiate into IL-17A-producing cells and are found in lesional skin

1 reference

12 December 2020

10.1007/S00018-017-2569-Y

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28624966%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28624966%20AND%20SRC:MED&resulttype=core&format=json