Novel therapy for therapy-resistant mantle cell lymphoma: multipronged approach with targeting of hedgehog signaling. (Q39363109)

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29 January 2020

title

Novel therapy for therapy-resistant mantle cell lymphoma: multipronged approach with targeting of hedgehog signaling (English)

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29 January 2020

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29 January 2020

Julie M Vose

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29 January 2020

Dennis D Weisenburger

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object named as

Dennis D Weisenburger

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29 January 2020

Philip J Bierman

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29 January 2020

Ganapati V Hegde

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29 January 2020

Shantaram S Joshi

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29 January 2020

Corey M Munger

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29 January 2020

Amit K Mittal

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29 January 2020

J Graham Sharp

series ordinal

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29 January 2020

language of work or name

English

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publication date

21 May 2012

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International Journal of Cancer

29 January 2020

published in

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29 January 2020

volume

131

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issue

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29 January 2020

page(s)

2951-2960

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Update on the molecular biology of mantle cell lymphoma

29 January 2020

cites work

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Mantle cell lymphoma: evolving novel options

21 January 2018

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Multiple-treatments meta-analysis of chemotherapy and targeted therapies in advanced breast cancer

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Phase 2 trial of rituximab plus hyper-CVAD alternating with rituximab plus methotrexate-cytarabine for relapsed or refractory aggressive mantle cell lymphoma

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Is the focus moving toward a combination of targeted drugs?

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Mechanisms of Hedgehog pathway activation in cancer and implications for therapy.

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Non-canonical activation of GLI transcription factors: implications for targeted anti-cancer therapy

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Inhibition of the hedgehog pathway in advanced basal-cell carcinoma

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Essential role of stromally induced hedgehog signaling in B-cell malignancies

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Targeting of sonic hedgehog-GLI signaling: a potential strategy to improve therapy for mantle cell lymphoma

21 January 2018

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Hedgehog-induced survival of B-cell chronic lymphocytic leukemia cells in a stromal cell microenvironment: a potential new therapeutic target

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Sonic hedgehog signaling proteins and ATP-binding cassette G2 are aberrantly expressed in diffuse large B-cell lymphoma.

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Hedgehog signaling pathway is activated in diffuse large B-cell lymphoma and contributes to tumor cell survival and proliferation.

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Sonic Hedgehog promotes multiple drug resistance by regulation of drug transport

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Hedgehog pathway inhibitor HhAntag691 is a potent inhibitor of ABCG2/BCRP and ABCB1/Pgp

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Expansion of Bcr-Abl-positive leukemic stem cells is dependent on Hedgehog pathway activation

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Proteasome inhibition with bortezomib: a new therapeutic strategy for non-Hodgkin's lymphoma

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Tumor regression in cancer patients by very low doses of a T cell-engaging antibody

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Adoptive immunotherapy for indolent non-Hodgkin lymphoma and mantle cell lymphoma using genetically modified autologous CD20-specific T cells

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Combined cyclophosphamide, vincristine, doxorubicin, and prednisone (CHOP) improves response rates but not survival and has lower hematologic toxicity compared with combined mitoxantrone, chlorambucil, and prednisone (MCP) in follicular and mantle c

21 January 2018

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Targeting AKT signaling sensitizes cancer to cellular immunotherapy

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Identification of cisplatin-resistance related genes in head and neck squamous cell carcinoma

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Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer

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Drug-selected human lung cancer stem cells: cytokine network, tumorigenic and metastatic properties

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Colorectal cancer stem cells are enriched in xenogeneic tumors following chemotherapy

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Recent advances in cancer stem/progenitor cell research: therapeutic implications for overcoming resistance to the most aggressive cancers

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ABCG2 is a direct transcriptional target of hedgehog signaling and involved in stroma-induced drug tolerance in diffuse large B-cell lymphoma.

21 January 2018

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Hedgehog signaling maintains chemoresistance in myeloid leukemic cells.

21 January 2018

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Gli1 is a potential target for alleviating multidrug resistance of gliomas

21 January 2018

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Nuclear survivin expression in mantle cell lymphoma is associated with cell proliferation and survival

21 January 2018

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The tumour microenvironment: a novel target for cancer therapy

21 January 2018

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Expression of the NF-κB targets BCL2 and BIRC5/Survivin characterizes small B-cell and aggressive B-cell lymphomas, respectively

21 January 2018

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