Junctional adhesion molecule-A is co-expressed with HER2 in breast tumors and acts as a novel regulator of HER2 protein degradation and signaling. (Q39321827)

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English	Junctional adhesion molecule-A is co-expressed with HER2 in breast tumors and acts as a novel regulator of HER2 protein degradation and signaling.	scientific article

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6 February 2020

Junctional adhesion molecule-A is co-expressed with HER2 in breast tumors and acts as a novel regulator of HER2 protein degradation and signaling (English)

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6 February 2020

Leonie S. Young

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6 February 2020

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6 February 2020

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6 February 2020

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E A McSherry

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6 February 2020

L Hudson

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6 February 2020

E W Kay

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6 February 2020

A D K Hill

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2 July 2012

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6 February 2020

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6 February 2020

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6 February 2020

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6 February 2020

2799-2804

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6 February 2020

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.276

21 January 2018

Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.276

21 January 2018

Molecular portraits of human breast tumours

1 reference

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21 January 2018

Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study

1 reference

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21 January 2018

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

1 reference

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21 January 2018

Novel anticancer targets: revisiting ERBB2 and discovering ERBB3.

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Lapatinib plus capecitabine for HER2-positive advanced breast cancer

1 reference

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21 January 2018

Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer

1 reference

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21 January 2018

Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer

1 reference

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21 January 2018

Occludin-mediated premature senescence is a fail-safe mechanism against tumorigenesis in breast carcinoma cells

1 reference

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21 January 2018

Epigenetic silencing of claudin-6 promotes anchorage-independent growth of breast carcinoma cells.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.276

21 January 2018

Increased claudin-4 expression is associated with poor prognosis and high tumour grade in breast cancer

1 reference

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21 January 2018

The claudin gene family: expression in normal and neoplastic tissues

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.276

21 January 2018

The Coxsackie-adenovirus receptor has elevated expression in human breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.276

21 January 2018

JAM-A expression positively correlates with poor prognosis in breast cancer patients

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.276

21 January 2018

Adaptation of core mechanisms to generate cell polarity

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.276

21 January 2018

The cell polarity protein ASIP/PAR-3 directly associates with junctional adhesion molecule (JAM)

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.276

21 January 2018

Junctional adhesion molecule 1 regulates epithelial cell morphology through effects on beta1 integrins and Rap1 activity.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.276

21 January 2018

JAM-1 is a ligand of the beta(2) integrin LFA-1 involved in transendothelial migration of leukocytes

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.276

21 January 2018

Attenuation of junctional adhesion molecule-A is a contributing factor for breast cancer cell invasion

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.276

21 January 2018

Abrogation of junctional adhesion molecule-A expression induces cell apoptosis and reduces breast cancer progression

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.276

21 January 2018

miR-145-dependent targeting of Junctional Adhesion Molecule A and modulation of fascin expression are associated with reduced breast cancer cell motility and invasiveness

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.276

21 January 2018

Breast cancer cell migration is regulated through junctional adhesion molecule-A-mediated activation of Rap1 GTPase.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.276

21 January 2018

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.276

21 January 2018

The effect of HER-2/neu overexpression on chemotherapeutic drug sensitivity in human breast and ovarian cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.276

21 January 2018

Lapatinib, a HER2 tyrosine kinase inhibitor, induces stabilization and accumulation of HER2 and potentiates trastuzumab-dependent cell cytotoxicity

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.276

21 January 2018

Co-targeting insulin-like growth factor I receptor and HER2: dramatic effects of HER2 inhibitors on nonoverexpressing breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.276

21 January 2018

Expression of junctional adhesion molecule-A prevents spontaneous and random motility.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.276

21 January 2018

Junctional adhesion molecule A interacts with Afadin and PDZ-GEF2 to activate Rap1A, regulate beta1 integrin levels, and enhance cell migration

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.276

21 January 2018

Degradation of HER2/neu by ANT2 shRNA suppresses migration and invasiveness of breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.276

21 January 2018

Phosphorylation and regulation of Raf by Akt (protein kinase B)

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.276

21 January 2018

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.276

21 January 2018

Akt/PKB promotes cancer cell invasion via increased motility and metalloproteinase production

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.276

21 January 2018

Oestradiol decreases colonic permeability through oestrogen receptor beta-mediated up-regulation of occludin and junctional adhesion molecule-A in epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.276

21 January 2018

Reexpression of the TJ protein CLDN1 induces apoptosis in breast tumor spheroids

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.276

31 March 2020

Characterization of huJAM: evidence for involvement in cell-cell contact and tight junction regulation

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.276

31 March 2020

Fibroblast growth factor-2 failed to induce angiogenesis in junctional adhesion molecule-A-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.276

31 March 2020

Identifiers

10.1038/ONC.2012.276

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22751120%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22751120%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

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