Elevated serine protease HtrA1 inhibits cell proliferation, reduces invasion, and induces apoptosis in esophageal squamous cell carcinoma by blocking the nuclear factor-κB signaling pathway (Q39256693)

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English	Elevated serine protease HtrA1 inhibits cell proliferation, reduces invasion, and induces apoptosis in esophageal squamous cell carcinoma by blocking the nuclear factor-κB signaling pathway	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

Elevated serine protease HtrA1 inhibits cell proliferation, reduces invasion, and induces apoptosis in esophageal squamous cell carcinoma by blocking the nuclear factor-κB signaling pathway (English)

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

apoptotic process

0 references

esophageal squamous cell carcinoma

1 reference

based on heuristic

inferred from title

author name string

Jin Xia

1

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

Feng Wang

2

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

Liuxing Wang

3

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

Qingxia Fan

4

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

publication date

19 October 2012

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Europe PubMed Central

PubMed publication ID

10 September 2017

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

34

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

317-328

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Europe PubMed Central

PubMed publication ID

10 September 2017

Primary structure of a putative serine protease specific for IGF-binding proteins

1 reference

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Localization of the gene for a serine protease with IGF-binding domain (PRSS11) to human chromosome 10q25.3-q26.2

1 reference

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21 January 2018

The HtrA1 serine protease is down-regulated during human melanoma progression and represses growth of metastatic melanoma cells

1 reference

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A candidate tumor suppressor HtrA1 is downregulated in ovarian cancer

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Serine protease HtrA1 modulates chemotherapy-induced cytotoxicity

1 reference

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Pattern of expression of HtrA1 during mouse development

1 reference

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Changes in mRNA and protein levels of human HtrA1, HtrA2 and HtrA3 in ovarian cancer

1 reference

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Serine proteases HTRA1 and HTRA3 are down-regulated with increasing grades of human endometrial cancer

1 reference

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21 January 2018

Retigeric acid B exhibits antitumor activity through suppression of nuclear factor-κB signaling in prostate cancer cells in vitro and in vivo

1 reference

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21 January 2018

The serine protease HtrA1 is upregulated in the human placenta during pregnancy.

1 reference

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Clinical implication of elevated human cervical cancer oncogene-1 expression in esophageal squamous cell carcinoma

1 reference

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RhoE functions as a tumor suppressor in esophageal squamous cell carcinoma and modulates the PTEN/PI3K/Akt signaling pathway

1 reference

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Cryptopleurine targets NF-κB pathway, leading to inhibition of gene products associated with cell survival, proliferation, invasion, and angiogenesis

1 reference

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

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21 January 2018

mTOR inhibitor rapamycin alone or combined with cisplatin inhibits growth of esophageal squamous cell carcinoma in nude mice

1 reference

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21 January 2018

Cyclin D1 is a NF-κB corepressor

1 reference

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Andrographolide Inhibits Oral Squamous Cell Carcinogenesis through NF-κB Inactivation

1 reference

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Histone methyltransferase NSD2/MMSET mediates constitutive NF-κB signaling for cancer cell proliferation, survival, and tumor growth via a feed-forward loop

1 reference

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Ganoderic acids suppress growth and angiogenesis by modulating the NF-κB signaling pathway in breast cancer cells

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Production of matrix metalloproteinase-9 by activated human monocytes involves a phosphatidylinositol-3 kinase/Akt/IKKalpha/NF-kappaB pathway

1 reference

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Overexpression of urokinase-type plasminogen activator in pancreatic adenocarcinoma is regulated by constitutively activated RelA

1 reference

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Prediction of central nervous system embryonal tumour outcome based on gene expression

1 reference

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21 January 2018

HtrA proteins as targets in therapy of cancer and other diseases.

1 reference

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21 January 2018

Expression and functional significance of HtrA1 loss in endometrial cancer

1 reference

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21 January 2018

Gene expression analysis of human prostate carcinoma during hormonal therapy identifies androgen-responsive genes and mechanisms of therapy resistance

1 reference

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Gene expression alterations in prostate cancer predicting tumor aggression and preceding development of malignancy

1 reference

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High-resolution global genomic survey of 178 gliomas reveals novel regions of copy number alteration and allelic imbalances

1 reference

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Expression of BCL10 in cervical cancer has a role in the regulation of cell growth through the activation of NF-κB-dependent cyclin D1 signaling

1 reference

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Glycogen synthase kinase-3β, NF-κB signaling, and tumorigenesis of human osteosarcoma.

1 reference

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NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling

1 reference

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21 January 2018

ErbB receptor tyrosine kinase/NF-κB signaling controls mammosphere formation in human breast cancer

1 reference

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NF-kappaB signaling pathway and its therapeutic implications in human diseases

1 reference

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NF-κB as a target for pancreatic cancer therapy.

1 reference

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21 January 2018

Using NF-κB as a molecular target for theranostics in radiation oncology research.

1 reference

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The NFκB pathway: a therapeutic target in glioblastoma

1 reference

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The emerging role of nuclear factor kappa B in renal cell carcinoma

1 reference

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21 January 2018

NF-kappaB in lung cancer, a carcinogenesis mediator and a prevention and therapy target

1 reference

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21 January 2018

NF-κB as a potential therapeutic target in myelodysplastic syndromes and acute myeloid leukemia

1 reference

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Oestrogen signalling inhibits invasive phenotype by repressing RelB and its target BCL2.

1 reference

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21 January 2018

Platelet-derived growth factor-D overexpression contributes to epithelial-mesenchymal transition of PC3 prostate cancer cells

1 reference

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The function of multiple IkappaB : NF-kappaB complexes in the resistance of cancer cells to Taxol-induced apoptosis

1 reference

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Blockade of NF-kappaB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis

1 reference

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Breast cancer metastasis suppressor 1 (BRMS1) inhibits osteopontin transcription by abrogating NF-kappaB activation

1 reference

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Integrative genomic and proteomic analysis of prostate cancer reveals signatures of metastatic progression

1 reference

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Antitumor effects of the novel NF-kappaB inhibitor dehydroxymethyl-epoxyquinomicin on human hepatic cancer cells: analysis of synergy with cisplatin and of possible correlation with inhibition of pro-survival genes and IL-6 production.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23079781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An activated Notch1 signaling pathway inhibits cell proliferation and induces apoptosis in human esophageal squamous cell carcinoma cell line EC9706.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23079781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene expression profiling of KBH-A42, a novel histone deacetylase inhibitor, in human leukemia and bladder cancer cell lines

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NFκB/p53 crosstalk-a promising new therapeutic target.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23079781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of HtrA1 serine protease expression in human lung cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23079781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NF-kappaB promotes breast cancer cell migration and metastasis by inducing the expression of the chemokine receptor CXCR4

1 reference

https://pubmed.ncbi.nlm.nih.gov/23079781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of human HtrA1, HtrA2, HtrA3 and TGF-beta1 genes in primary endometrial cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/23079781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

S100A7 promotes the migration and invasion of osteosarcoma cells via the receptor for advanced glycation end products

1 reference

https://pubmed.ncbi.nlm.nih.gov/23079781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NSCLC and the alternative pathway of NF-κB: uncovering an unknown relation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23079781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serine protease HtrA1 expression in human hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/23079781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of gene expression identifies candidate markers and pharmacological targets in prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/23079781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S13277-012-0553-6

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

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