In vivo profiling of seven common opioids for antinociception, constipation and respiratory depression: no two opioids have the same profile (Q39209988)

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scientific article published on July 2014

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English	In vivo profiling of seven common opioids for antinociception, constipation and respiratory depression: no two opioids have the same profile	scientific article published on July 2014

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

10 September 2017

In vivo profiling of seven common opioids for antinociception, constipation and respiratory depression: no two opioids have the same profile (English)

1 reference

Europe PubMed Central

PMC publication ID

10 September 2017

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1 reference

based on heuristic

inferred from title

4

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Europe PubMed Central

PMC publication ID

10 September 2017

author name string

A Kuo

1

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Europe PubMed Central

PMC publication ID

10 September 2017

B D Wyse

2

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Europe PubMed Central

PMC publication ID

10 September 2017

W Meutermans

3

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Europe PubMed Central

PMC publication ID

10 September 2017

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publication date

1 July 2014

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Europe PubMed Central

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10 September 2017

British Journal of Pharmacology

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Europe PubMed Central

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10 September 2017

172

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Europe PubMed Central

PMC publication ID

10 September 2017

2

1 reference

Europe PubMed Central

PMC publication ID

10 September 2017

532-548

1 reference

Europe PubMed Central

PMC publication ID

10 September 2017

Challenges for opioid receptor nomenclature: IUPHAR Review 9.

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The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptors

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Efficacy and ligand bias at the μ-opioid receptor

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292966

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Opioid receptors: toward separation of analgesic from undesirable effects

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292966

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Synthesis and biological evaluation of an orally active glycosylated endomorphin-1.

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10 September 2017

Buprenorphine metabolites, buprenorphine-3-glucuronide and norbuprenorphine-3-glucuronide, are biologically active

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292966

10 September 2017

Opioid receptor subtypes: fact or artifact?

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292966

10 September 2017

Animal research: reporting in vivo experiments: the ARRIVE guidelines

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μ-opioid receptors: correlation of agonist efficacy for signalling with ability to activate internalization

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10 September 2017

Differences between and combinations of opioids re-visited

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292966

10 September 2017

Oxycodone and morphine have distinctly different pharmacological profiles: radioligand binding and behavioural studies in two rat models of neuropathic pain

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292966

10 September 2017

Opioid-induced respiratory effects: new data on buprenorphine

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292966

10 September 2017

Pharmacokinetics and pharmacodynamics of oral oxycodone in healthy human subjects: role of circulating active metabolites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292966

10 September 2017

Endogenous orphanin FQ/nociceptin is involved in the development of morphine tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292966

10 September 2017

Peripheral kappa-opioid agonists for visceral pain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292966

10 September 2017

Drug delivery to the central nervous system: a review

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292966

10 September 2017

Management of opioid-induced constipation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292966

10 September 2017

G-protein-coupled receptor heterodimerization modulates receptor function

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Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications.

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10 September 2017

The intrinsic antinociceptive effects of oxycodone appear to be κ -opioid receptor mediated

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292966

10 September 2017

Interaction of U-69,593 with mu-, alpha- and kappa-opioid binding sites and its analgesic and intestinal effects in rats

1 reference

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10 September 2017

Antidiarrheal properties of supraspinal mu and delta and peripheral mu, delta and kappa opioid receptors: inhibition of diarrhea without constipation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292966

10 September 2017

Influence of polarity on dose-response relationships of intrathecal opioids in rats

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292966

10 September 2017

Adverse effects of systemic opioid analgesics

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10 September 2017

Antidiarrheal and colonic antipropulsive effects of spinal and supraspinal administration of the natural delta opioid receptor agonist, [D-Ala2]deltorphin II, in the rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292966

10 September 2017

Regulation of gastrointestinal function by multiple opioid receptors

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292966

10 September 2017

Cerebrospinal fluid and plasma concentrations of morphine, morphine-3-glucuronide, and morphine-6-glucuronide in patients before and after initiation of intracerebroventricular morphine for cancer pain management.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292966

10 September 2017

Guidelines for reporting experiments involving animals: the ARRIVE guidelines

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10 September 2017

Morphine-like opiates selectively antagonize receptor-arrestin interactions.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292966

14 September 2017

Principles of opioid pharmacotherapy: practical implications of basic mechanisms

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25 September 2017

Ventilatory function assessment in safety pharmacology: optimization of rodent studies using normocapnic or hypercapnic conditions

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15 June 2018

Sex-related differences in antinociception and tolerance development following chronic intravenous infusion of morphine in the rat: modulatory role of testosterone via morphine clearance

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292966

15 June 2018

Differential binding properties of oripavines at cloned mu- and delta-opioid receptors

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15 June 2018

In vivo dynamics and distribution of intracerebroventricularly administered gadodiamide, visualized by magnetic resonance imaging

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15 June 2018

Pharmacological study of dihydroetorphine in cloned mu-, delta- and kappa-opioid receptors

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15 June 2018

Liposolubility and protein binding of oxycodone in vitro

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15 June 2018

Interaction of naloxone with mu- and delta-opioid agonists on the respiration of rats

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15 June 2018

Bremazocine: A potent, long-acting opiate kappa-agonist

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15 June 2018

Roles of mu, delta and kappa opioid receptors in spinal and supraspinal mediation of gastrointestinal transit effects and hot-plate analgesia in the mouse

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15 June 2018

The cerebral ventricles of the rat

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15 June 2018

[3H]U-69593 a highly selective ligand for the opioid kappa receptor

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15 June 2018

Separation of opioid analgesia from respiratory depression: evidence for different receptor mechanisms

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15 June 2018

Morphine-6-glucuronide: analgesic effects and receptor binding profile in rats

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15 June 2018

Morphine 6-glucuronide and morphine 3-glucuronide as molecular chameleons with unexpected lipophilicity

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15 June 2018

Role of excitatory amino acids in the generation and transmission of respiratory drive in neonatal rat.

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15 June 2018

Opioid-induced depression in the lamprey respiratory network

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21 August 2018

Antinociception by spinal and systemic oxycodone: why does the route make a difference? In vitro and in vivo studies in rats.

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21 August 2018

Morphine side effects in beta-arrestin 2 knockout mice

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21 August 2018

Intracerebroventricular and intrathecal injectate spread in rats

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21 August 2018

A preclinical comparison between different opioids: antinociceptive versus adverse effects

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21 August 2018

Peripheral versus central antinociceptive actions of 6-amino acid-substituted derivatives of 14-O-methyloxymorphone in acute and inflammatory pain in the rat.

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21 August 2018

Comparison of morphine-6-glucuronide and morphine on respiratory depressant and antinociceptive responses in wild type and mu-opioid receptor deficient mice

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21 August 2018

Evidence for an active transport of morphine-6-beta-d-glucuronide but not P-glycoprotein-mediated at the blood-brain barrier.

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21 August 2018

Kappa Opioid Receptor Activation in the Nucleus Accumbens Inhibits Glutamate and GABA Release Through Different Mechanisms

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21 August 2018

Supraspinal antinociceptive effects of mu and delta agonists involve modulation of adenosine uptake

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21 August 2018

Kinetics of respiratory depression in rats induced by buprenorphine and its metabolite, norbuprenorphine.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292966

21 August 2018

Comparison of epidural morphine and oxycodone for pain after abdominal surgery

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21 August 2018

Apparent pA2 analysis on the respiratory depressant effects of alfentanil, etonitazene, ethylketocyclazocine (EKC) and Mr2033 in rhesus monkeys.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292966

21 August 2018

Centrally mediated inhibition of small intestinal transit and motility by morphine in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292966

21 August 2018

Bremazocine induces antinociception, but prevents opioid-induced constipation and catatonia in rats and precipitates withdrawal in morphine-dependent rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292966

21 August 2018

The antinociceptive potencies of oxycodone, noroxycodone and morphine after intracerebroventricular administration to rats

1 reference

https://api.crossref.org/works/10.1111%2FBPH.12696

21 January 2018

Quantitation of Morphine, Morphine-3-Glucuronide, and Morphine-6-Glucuronide in Plasma and Cerebrospinal Fluid Using Solid-Phase Extraction and High-Performance Liquid Chromatography with Electrochemical Detection

1 reference

https://api.crossref.org/works/10.1111%2FBPH.12696

21 January 2018

Respiratory depression produced by activation of GABA receptors in hindbrain of cat

1 reference

https://pubmed.ncbi.nlm.nih.gov/24641546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Respiratory effects of morphine in awake unrestrained rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/24641546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Incomplete, asymmetric, and route-dependent cross-tolerance between oxycodone and morphine in the Dark Agouti rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/24641546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracerebroventricular morphine, analgesia, and nociceptive spinal reflexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/24641546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intestinal effect of morphine 6-glucuronide: in vivo and in vitro characterization

1 reference

https://pubmed.ncbi.nlm.nih.gov/24641546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative analysis of buprenorphine- and norbuprenorphine-induced analgesic effects based on pharmacokinetic-pharmacodynamic modeling

1 reference

https://pubmed.ncbi.nlm.nih.gov/24641546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of nociceptin, an endogenous ligand for the ORL1 receptor, on rat colonic contraction and transit

1 reference

https://pubmed.ncbi.nlm.nih.gov/24641546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripheral and central actions of orphanin FQ (nociceptin) on murine colon

1 reference

https://pubmed.ncbi.nlm.nih.gov/24641546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/BPH.12696

1 reference

Europe PubMed Central

PMC publication ID

10 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 September 2017

ResearchGate publication ID

0 references

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