A small molecule AMPK activator protects the heart against ischemia-reperfusion injury. (Q39100111)

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25 January 2020

title

A small molecule AMPK activator protects the heart against ischemia-reperfusion injury (English)

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25 January 2020

1 reference

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25 January 2020

Agnes S Kim

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25 January 2020

Tracy M Wright

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25 January 2020

Ji Li

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25 January 2020

Dake Qi

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25 January 2020

Kwame Atsina

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25 January 2020

Vlad Zaha

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25 January 2020

Kei Sakamoto

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25 January 2020

Lawrence H Young

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publication date

29 March 2011

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Journal of Molecular and Cellular Cardiology

25 January 2020

published in

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volume

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issue

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page(s)

24-32

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describes a project that uses

25 January 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4005884/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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AMP-activated protein kinase deficiency enhances myocardial ischemia/reperfusion injury but has minimal effect on the antioxidant/antinitrative protection of adiponectin

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Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome

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Activation of AMPK alpha- and gamma-isoform complexes in the intact ischemic rat heart

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AMP-activated protein kinase protects cardiomyocytes against hypoxic injury through attenuation of endoplasmic reticulum stress

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Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2-dependent mechanisms

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AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury

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Stimulation of the AMP-activated protein kinase leads to activation of eukaryotic elongation factor 2 kinase and to its phosphorylation at a novel site, serine 398

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Contraction-Induced Fatty Acid Translocase/CD36 Translocation in Rat Cardiac Myocytes Is Mediated Through AMP-Activated Protein Kinase Signaling

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Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia

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Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain

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Characterization of AMP-activated protein kinase gamma-subunit isoforms and their role in AMP binding

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High rates of fatty acid oxidation during reperfusion of ischemic hearts are associated with a decrease in malonyl-CoA levels due to an increase in 5'-AMP-activated protein kinase inhibition of acetyl-CoA carboxylase

21 August 2018

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Temperature preconditioning of isolated rat hearts--a potent cardioprotective mechanism involving a reduction in oxidative stress and inhibition of the mitochondrial permeability transition pore

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7 January 2021

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7 January 2021

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7 January 2021

Identifiers

DOI

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25 January 2020

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25 January 2020

PubMed publication ID

21402077

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