miR-219-1-3p is a negative regulator of the mucin MUC4 expression and is a tumor suppressor in pancreatic cancer. (Q39017335)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24608432%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

title

miR-219-1-3p is a negative regulator of the mucin MUC4 expression and is a tumor suppressor in pancreatic cancer (English)

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10 March 2020

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10 March 2020

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10 March 2020

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10 March 2020

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10 March 2020

Isabelle Van Seuningen

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10 March 2020

F Lahdaoui

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10 March 2020

Y Delpu

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10 March 2020

M Messager

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10 March 2020

E Leteurtre

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10 March 2020

C Mariette

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10 March 2020

J Torrisani

1 reference

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10 March 2020

language of work or name

English

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publication date

10 March 2014

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10 March 2020

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10 March 2020

volume

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10 March 2020

issue

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10 March 2020

page(s)

780-788

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10 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.11

The mucin MUC4 and its membrane partner ErbB2 regulate biological properties of human CAPAN-2 pancreatic cancer cells via different signalling pathways

21 January 2018

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The membrane-bound mucins: From cell signalling to transcriptional regulation and expression in epithelial cancers.

21 January 2018

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The MUC4 mucin mediates gemcitabine resistance of human pancreatic cancer cells via the Concentrative Nucleoside Transporter family.

21 January 2018

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Epigenetic regulation of the human mucin gene MUC4 in epithelial cancer cell lines involves both DNA methylation and histone modifications mediated by DNA methyltransferases and histone deacetylases

21 January 2018

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A role for human MUC4 mucin gene, the ErbB2 ligand, as a target of TGF-beta in pancreatic carcinogenesis.

21 January 2018

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Epigenetics and genetics. MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy

21 January 2018

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miRNA in clinical practice: pancreatic cancer.

21 January 2018

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MicroRNAs: genomics, biogenesis, mechanism, and function

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MicroRNA signatures in human cancers

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MicroRNA expression profiles classify human cancers

21 January 2018

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MicroRNA-150 directly targets MUC4 and suppresses growth and malignant behavior of pancreatic cancer cells

21 January 2018

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MUC4 potentiates invasion and metastasis of pancreatic cancer cells through stabilization of fibroblast growth factor receptor 1.

21 January 2018

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MUC4 mucin interacts with and stabilizes the HER2 oncoprotein in human pancreatic cancer cells

21 January 2018

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MUC4 mucin potentiates pancreatic tumor cell proliferation, survival, and invasive properties and interferes with its interaction to extracellular matrix proteins.

21 January 2018

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The membrane-bound mucins: how large O-glycoproteins play key roles in epithelial cancers and hold promise as biological tools for gene-based and immunotherapies

21 January 2018

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Mucins and pancreatic cancer.

21 January 2018

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Characterization of human mucin gene MUC4 promoter: importance of growth factors and proinflammatory cytokines for its regulation in pancreatic cancer cells.

21 January 2018

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Synergistic induction of the MUC4 mucin gene by interferon-gamma and retinoic acid in human pancreatic tumour cells involves a reprogramming of signalling pathways.

21 January 2018

1 reference

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MUC4 expression is regulated by cystic fibrosis transmembrane conductance regulator in pancreatic adenocarcinoma cells via transcriptional and post-translational mechanisms

21 January 2018

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microRNA modulation of circadian-clock period and entrainment

21 January 2018

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Dicer1 and miR-219 Are required for normal oligodendrocyte differentiation and myelination

21 January 2018

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MicroRNA-mediated control of oligodendrocyte differentiation

21 January 2018

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Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers

21 January 2018

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MicroRNA (miRNA) transcriptome of mouse retina and identification of a sensory organ-specific miRNA cluster

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MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis

21 January 2018

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Expression profiling identifies microRNA signature in pancreatic cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.11

MicroRNA expression alterations are linked to tumorigenesis and non-neoplastic processes in pancreatic ductal adenocarcinoma

21 January 2018

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MicroRNA alterations of pancreatic intraepithelial neoplasias

21 January 2018

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MicroRNA-21 is induced early in pancreatic ductal adenocarcinoma precursor lesions

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The p16-specific reactivation and inhibition of cell migration through demethylation of CpG islands by engineered transcription factors

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Transcription of SST2 somatostatin receptor gene in human pancreatic cancer cells is altered by single nucleotide promoter polymorphism.

21 January 2018

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let-7 MicroRNA transfer in pancreatic cancer-derived cells inhibits in vitro cell proliferation but fails to alter tumor progression

21 January 2018

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The use of targeted mouse models for preclinical testing of novel cancer therapeutics.

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Capture of microRNA-bound mRNAs identifies the tumor suppressor miR-34a as a regulator of growth factor signaling

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Sequence of the 5'-flanking region and promoter activity of the human mucin gene MUC5B in different phenotypes of colon cancer cells

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Regulation of the human mucin MUC4 by taurodeoxycholic and taurochenodeoxycholic bile acids in oesophageal cancer cells is mediated by hepatocyte nuclear factor 1alpha.

21 January 2018

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The human mucin MUC4 is transcriptionally regulated by caudal-related homeobox, hepatocyte nuclear factors, forkhead box A, and GATA endodermal transcription factors in epithelial cancer cells.

21 January 2018

1 reference

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The murine Muc2 mucin gene is transcriptionally regulated by the zinc-finger GATA-4 transcription factor in intestinal cells

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MUC4 expression increases progressively in pancreatic intraepithelial neoplasia

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MicroRNA expression profiles associated with pancreatic adenocarcinoma and ampullary adenocarcinoma

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Frequent amplification of 8q24, 11q, 17q, and 20q-specific genes in pancreatic cancer

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31 March 2020

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PubMed

https://pubmed.ncbi.nlm.nih.gov/24608432

inferred from PubMed ID database lookup

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Identification of chromosomal imbalances in pancreatic carcinoma using comparative genomic hybridization

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https://pubmed.ncbi.nlm.nih.gov/24608432

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Long-term culture and immortalization of epithelial cells from normal adult human pancreatic ducts transfected by the E6E7 gene of human papilloma virus 16.

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