Evaluation of the insulin-releasing and glucose-lowering effects of GPR120 activation in pancreatic β-cells. (Q38985790)

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20 March 2020

title

Evaluation of the insulin-releasing and glucose-lowering effects of GPR120 activation in pancreatic β-cells (English)

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20 March 2020

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Yasser H.A Abdel-Wahab

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20 March 2020

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20 March 2020

B M Moran

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20 March 2020

A M McKillop

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publication date

9 July 2014

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Diabetes, Obesity and Metabolism

20 March 2020

published in

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volume

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issue

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page(s)

1128-1139

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Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120

20 March 2020

cites work

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Agonism with the omega-3 fatty acids alpha-linolenic acid and docosahexaenoic acid mediates phosphorylation of both the short and long isoforms of the human GPR120 receptor

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Cloning, expression, and pharmacological characterization of the GPR120 free fatty acid receptor from cynomolgus monkey: comparison with human GPR120 splice variants

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Structural requirements for the cytoprotective actions of mono-unsaturated fatty acids in the pancreatic beta-cell line, BRIN-BD11

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Taste Preference for Fatty Acids Is Mediated by GPR40 and GPR120

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The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids

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The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids

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Activation of GPR119 by fatty acid agonists augments insulin release from clonal β-cells and isolated pancreatic islets and improves glucose tolerance in mice.

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Evaluation of the insulin releasing and antihyperglycaemic activities of GPR55 lipid agonists using clonal beta-cells, isolated pancreatic islets and mice

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GPR40-induced insulin secretion by the novel agonist TAK-875: first clinical findings in patients with type 2 diabetes

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GW9508 inhibits insulin secretion by activating ATP-sensitive potassium channels in rat pancreatic β-cells

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A practical note on the use of cytotoxicity assays.

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Protective action of arachidonic acid against alloxan-induced cytotoxicity and diabetes mellitus

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Omega-3 and omega-6 PUFAs induce the same GPR120-mediated signalling events, but with different kinetics and intensity in Caco-2 cells.

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Free fatty acids and protein kinase C activation induce GPR120 (free fatty acid receptor 4) phosphorylation.

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