The quest for host targets to combat dengue virus infections (Q38959485)

8 September 2017

1 reference

title

The quest for host targets to combat dengue virus infections (English)

1 reference

8 September 2017

1 reference

viral genome replication

1 reference

based on heuristic

inferred from abstract

virion assembly

1 reference

based on heuristic

inferred from abstract

Ralf Bartenschlager

0 references

Eliana G Acosta

1 reference

8 September 2017

publication date

17 September 2016

1 reference

Current opinion in virology

8 September 2017

published in

1 reference

8 September 2017

1 reference

8 September 2017

page(s)

47-54

1 reference

The global distribution and burden of dengue

8 September 2017

cites work

2 references

21 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1038/NATURE12060

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

TIM-family proteins promote infection of multiple enveloped viruses through virion-associated phosphatidylserine

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Essential Role of Cyclophilin A for Hepatitis C Virus Replication and Virus Production and Possible Link to Polyprotein Cleavage Kinetics

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Sulfated polysaccharide, curdlan sulfate, efficiently prevents entry/fusion and restricts antibody-dependent enhancement of dengue virus infection in vitro: a possible candidate for clinical application

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

A Dengue Fever Viremia Model in Mice Shows Reduction in Viral Replication and Suppression of the Inflammatory Response after Treatment with Antiviral Drugs

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Discovery of Dengue Virus NS4B Inhibitors

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Statins reduce dengue virus production via decreased virion assembly

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Alternative infectious entry pathways for dengue virus serotypes into mammalian cells

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Cholesterol biosynthesis modulation regulates dengue viral replication

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Novel dengue virus inhibitor 4-HPR activates ATF4 independent of protein kinase R-like Endoplasmic Reticulum Kinase and elevates levels of eIF2α phosphorylation in virus infected cells

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Antiviral effect of the heparan sulfate mimetic, PI-88, against dengue and encephalitic flaviviruses

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Flaviviridae Replication Organelles: Oh, What a Tangled Web We Weave

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Dengue virus infection perturbs lipid homeostasis in infected mosquito cells

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Dengue Virus Modulates the Unfolded Protein Response in a Time-dependent Manner

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Lovastatin delays infection and increases survival rates in AG129 mice infected with dengue virus serotype 2

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Human DDX3 protein is a valuable target to develop broad spectrum antiviral agents

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Proteasome Inhibition Suppresses Dengue Virus Egress in Antibody Dependent Infection

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Revisiting dengue virus-host cell interaction: new insights into molecular and cellular virology

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Multiple functions of DDX3 RNA helicase in gene regulation, tumorigenesis, and viral infection

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Synergistic suppression of dengue virus replication using a combination of nucleoside analogs and nucleoside synthesis inhibitors

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

The cyclophilin inhibitor SCY-635 suppresses viral replication and induces endogenous interferons in patients with chronic HCV genotype 1 infection

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

A small-molecule inhibitor of deubiquitinating enzyme USP14 inhibits Dengue virus replication

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Efficacy and safety of celgosivir in patients with dengue fever (CELADEN): a phase 1b, randomised, double-blind, placebo-controlled, proof-of-concept trial

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Synergy of entry inhibitors with direct-acting antivirals uncovers novel combinations for prevention and treatment of hepatitis C.

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Dengue Virus Capsid Protein Usurps Lipid Droplets for Viral Particle Formation

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

A randomized controlled trial of chloroquine for the treatment of dengue in Vietnamese adults

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Dengue Virus Non-structural Protein 1 Modulates Infectious Particle Production via Interaction with the Structural Proteins

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Targeting dengue virus NS4B protein for drug discovery

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Novel DL-galactan hybrids from the red seaweed Gymnogongrus torulosus are potent inhibitors of herpes simplex virus and dengue virus

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Acidotropic amines inhibit proteolytic processing of flavivirus prM protein

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Dengue vaccine: hypotheses to understand CYD-TDV-induced protection

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

The bioactive lipid 4-hydroxyphenyl retinamide inhibits flavivirus replication

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Cyclosporine Inhibits Flavivirus Replication through Blocking the Interaction between Host Cyclophilins and Viral NS5 Protein

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Vaccine and Wild-Type Strains of Yellow Fever Virus Engage Distinct Entry Mechanisms and Differentially Stimulate Antiviral Immune Responses.

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Dengue-3 Virus Entry into Vero Cells: Role of Clathrin-Mediated Endocytosis in the Outcome of Infection

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Paradoxical role of antibodies in dengue virus infections: considerations for prophylactic vaccine development

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Optimizing celgosivir therapy in mouse models of dengue virus infection of serotypes 1 and 2: The search for a window for potential therapeutic efficacy

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Requirement of cholesterol in the viral envelope for dengue virus infection

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

U18666A, an intra-cellular cholesterol transport inhibitor, inhibits dengue virus entry and replication

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Characterization of dengue virus resistance to brequinar in cell culture

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Interference in dengue virus adsorption and uncoating by carrageenans

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

The TIM and TAM families of phosphatidylserine receptors mediate dengue virus entry

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Broad antiviral activity of carbohydrate-binding agents against the four serotypes of dengue virus in monocyte-derived dendritic cells

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Biochemical and morphological properties of hepatitis C virus particles and determination of their lipidome

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Appraising the roles of CBLL1 and the ubiquitin/proteasome system for flavivirus entry and replication

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Repurposing of prochlorperazine for use against dengue virus infection

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

The small molecules AZD0530 and dasatinib inhibit dengue virus RNA replication via Fyn kinase.

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Dose- and schedule-dependent protective efficacy of celgosivir in a lethal mouse model for dengue virus infection informs dosing regimen for a proof of concept clinical trial.

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Prophylactic ribavirin treatment of dengue type 1 infection in rhesus monkeys

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Flavivirus entry receptors: an update

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Dendritic-cell-specific ICAM3-grabbing non-integrin is essential for the productive infection of human dendritic cells by mosquito-cell-derived dengue viruses

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

ER stress, autophagy, and RNA viruses

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Alpha-glucosidase inhibitors reduce dengue virus production by affecting the initial steps of virion morphogenesis in the endoplasmic reticulum

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Japanese encephalitis virus infects neuronal cells through a clathrin-independent endocytic mechanism

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

A nuclear transport inhibitor that modulates the unfolded protein response and provides in vivo protection against lethal dengue virus infection.

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

The increase in cholesterol levels at early stages after dengue virus infection correlates with an augment in LDL particle uptake and HMG-CoA reductase activity

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Antiviral activity of carbohydrate-binding agents and the role of DC-SIGN in dengue virus infection

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Celgosivir treatment misfolds dengue virus NS1 protein, induces cellular pro-survival genes and protects against lethal challenge mouse model

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Polyunsaturated liposomes are antiviral against hepatitis B and C viruses and HIV by decreasing cholesterol levels in infected cells

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Effects of hypolipidemic agent nordihydroguaiaretic acid on lipid droplets and hepatitis C virus

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Iminosugars Inhibit Dengue Virus Production via Inhibition of ER Alpha-Glucosidases--Not Glycolipid Processing Enzymes

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Dengue virus serotype infection specifies the activation of the unfolded protein response

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Host Gene Expression Profiling of Dengue Virus Infection in Cell Lines and Patients

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Characterization of the early events in dengue virus cell entry by biochemical assays and single-virus tracking

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Virion-associated phosphatidylethanolamine promotes TIM1-mediated infection by Ebola, dengue, and West Nile viruses

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Chloroquine use improves dengue-related symptoms

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Dengue virus infectivity depends on envelope protein binding to target cell heparan sulfate

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Ten years of dengue drug discovery: progress and prospects

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Nordihydroguaiaretic acid (NDGA) inhibits replication and viral morphogenesis of dengue virus

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

A multivalent inhibitor of the DC-SIGN dependent uptake of HIV-1 and Dengue virus

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Inhibition of Dengue Virus through Suppression of Host Pyrimidine Biosynthesis

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

The predominant mechanism by which ribavirin exerts its antiviral activity in vitro against flaviviruses and paramyxoviruses is mediated by inhibition of IMP dehydrogenase

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Dengue virus nonstructural protein 3 redistributes fatty acid synthase to sites of viral replication and increases cellular fatty acid synthesis

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Antiviral activity of chloroquine against dengue virus type 2 replication in Aotus monkeys

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

A Combined Genetic-Proteomic Approach Identifies Residues within Dengue Virus NS4B Critical for Interaction with NS3 and Viral Replication

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Antiviral therapies targeting host ER alpha-glucosidases: current status and future directions

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Receptors and routes of dengue virus entry into the host cells

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

The cyclophilin inhibitor Debio 025 combined with PEG IFNalpha2a significantly reduces viral load in treatment-naïve hepatitis C patients.

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

The antiviral activity of sulfated polysaccharides against dengue virus is dependent on virus serotype and host cell.

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

Cyclophilin inhibitors as antiviral agents

1 November 2022

1 reference

https://api.crossref.org/works/10.1016/J.COVIRO.2016.09.003

10.1016/J.COVIRO.2016.09.003

1 November 2022

Identifiers

DOI

1 reference

8 September 2017

1 reference