A carbazole alkaloid deactivates mTOR through the suppression of rictor and that induces apoptosis in lung cancer cells (Q38884605)

7 September 2017

title

A carbazole alkaloid deactivates mTOR through the suppression of rictor and that induces apoptosis in lung cancer cells (English)

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7 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25893736%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Priyajit Chatterjee

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9 June 2020

Soma Seal

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9 June 2020

Sandip Mukherjee

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9 June 2020

Mantu Bhuyan

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9 June 2020

Nabin C Barua

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9 June 2020

Pranab K Baruah

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9 June 2020

Santi Prasad Sinha Babu

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9 June 2020

Samir Bhattacharya

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9 June 2020

publication date

17 April 2015

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Molecular and Cellular Biochemistry

7 September 2017

published in

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9 June 2020

volume

405

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9 June 2020

issue

1-2

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9 June 2020

page(s)

149-158

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Molecular characteristics of non-small cell lung cancer

9 June 2020

cites work

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Cyclin D1 overexpression is an indicator of poor prognosis in resectable non-small cell lung cancer

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Inhibition of protein kinase B/Akt. implications for cancer therapy

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The PI3K-PDK1 connection: more than just a road to PKB

21 January 2018

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

21 January 2018

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Phosphorylated Akt overexpression and loss of PTEN expression in non-small cell lung cancer confers poor prognosis

21 January 2018

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TORC-specific phosphorylation of mammalian target of rapamycin (mTOR): phospho-Ser2481 is a marker for intact mTOR signaling complex 2.

21 January 2018

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Bexarotene in combination with chemotherapy fails to prolong survival in patients with advanced non-small-cell lung cancer: results from the SPIRIT I and II trials

21 January 2018

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Mahanine inhibits growth and induces apoptosis in prostate cancer cells through the deactivation of Akt and activation of caspases

21 January 2018

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Vapor of volatile oils from Litsea cubeba seed induces apoptosis and causes cell cycle arrest in lung cancer cells

21 January 2018

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Adipocyte fetuin-A contributes to macrophage migration into adipose tissue and polarization of macrophages.

21 January 2018

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Phosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase A

21 January 2018

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FKBP51 affects cancer cell response to chemotherapy by negatively regulating Akt.

21 January 2018

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Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

21 January 2018

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Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1

21 January 2018

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mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice

21 January 2018

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Rictor is a novel target of p70 S6 kinase-1.

21 January 2018

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Targeting mTOR: prospects for mTOR complex 2 inhibitors in cancer therapy

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Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation

21 January 2018

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12 December 2020

PTEN and phosphorylated AKT expression and prognosis in early- and late-stage non-small cell lung cancer

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12 December 2020

Overexpression of cyclin B1 in early-stage non-small cell lung cancer and its clinical implication

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12 December 2020

p53 gene mutations are associated with shortened survival in patients with advanced non-small cell lung cancer: an analysis of medically managed patients

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12 December 2020

Loss of Fhit is frequent in stage I non-small cell lung cancer and in the lungs of chronic smokers

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12 December 2020

Response to epidermal growth factor receptor inhibitors in non-small cell lung cancer cells: limited antiproliferative effects and absence of apoptosis associated with persistent activity of extracellular signal-regulated kinase or Akt kinase pathwa

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12 December 2020

Prevention of phosphatidylinositol 3'-kinase-Akt survival signaling pathway during topotecan-induced apoptosis

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12 December 2020

Mechanisms of p16INK4A inactivation in non small-cell lung cancers

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12 December 2020

Prognostic significance of cyclin E overexpression in resected non-small cell lung cancer

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12 December 2020

10.1007/S11010-015-2406-2

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25893736%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

9 June 2020

1017763407

0 references

1 reference

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