S1P Signaling and De Novo Biosynthesis in Blood Pressure Homeostasis (Q38869085)

7 September 2017

1 reference

title

S1P Signaling and De Novo Biosynthesis in Blood Pressure Homeostasis (English)

1 reference

7 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27317800%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Anna Cantalupo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27317800%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

language of work or name

English

0 references

publication date

17 June 2016

1 reference

Journal of Pharmacology and Experimental Therapeutics

7 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27317800%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

volume

358

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27317800%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27317800%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

page(s)

359-370

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27317800%20AND%20SRC:MED&resulttype=core&format=json

Nogo-B regulates endothelial sphingolipid homeostasis to control vascular function and blood pressure

9 June 2020

cites work

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HDL-bound sphingosine 1-phosphate acts as a biased agonist for the endothelial cell receptor S1P1 to limit vascular inflammation

9 September 2017

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Inhibition of Sphingosine Kinase 1 Ameliorates Angiotensin II-Induced Hypertension and Inhibits Transmembrane Calcium Entry via Store-Operated Calcium Channel

9 September 2017

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CFTR and sphingolipids mediate hypoxic pulmonary vasoconstriction

9 September 2017

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Imaging S1P1 activation in vivo

9 September 2017

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Individual variation of human S1P₁ coding sequence leads to heterogeneity in receptor function and drug interactions

9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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The clinically-tested S1P receptor agonists, FTY720 and BAF312, demonstrate subtype-specific bradycardia (S1P₁) and hypertension (S1P₃) in rat

9 September 2017

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Effect of sphingosine kinase 1 inhibition on blood pressure

9 September 2017

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Flow-regulated endothelial S1P receptor-1 signaling sustains vascular development

9 September 2017

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Sphingosine kinase type 2 inhibition elevates circulating sphingosine 1-phosphate

9 September 2017

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Ceramide mediates vascular dysfunction in diet-induced obesity by PP2A-mediated dephosphorylation of the eNOS-Akt complex

9 September 2017

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The role of sphingosine kinase 1/sphingosine-1-phosphate pathway in the myogenic tone of posterior cerebral arteries.

9 September 2017

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The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice

9 September 2017

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Antihypertensive treatment differentially affects vascular sphingolipid biology in spontaneously hypertensive rats

9 September 2017

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Sphingosine-1-phosphate and lymphocyte egress from lymphoid organs

9 September 2017

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Sphingolipid and glycosphingolipid metabolic pathways in the era of sphingolipidomics

9 September 2017

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Regulation of mammalian physiology, development, and disease by the sphingosine 1-phosphate and lysophosphatidic acid receptors

9 September 2017

1 reference

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Hypertension is associated with marked alterations in sphingolipid biology: a potential role for ceramide

9 September 2017

1 reference

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Endothelium-protective sphingosine-1-phosphate provided by HDL-associated apolipoprotein M

9 September 2017

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An Overview of Sphingolipid Metabolism: From Synthesis to Breakdown

9 September 2017

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Vessel-specific role of sphingosine kinase 1 in the vasoconstriction of isolated basilar arteries

9 September 2017

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Sphingosine 1-phosphate and cancer

9 September 2017

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Sphingosine kinase 1 and sphingosine-1-phosphate receptor 2 are vital to recovery from anaphylactic shock in mice.

9 September 2017

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Orm family proteins mediate sphingolipid homeostasis

9 September 2017

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Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis

9 September 2017

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A placebo-controlled trial of oral fingolimod in relapsing multiple sclerosis

9 September 2017

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FTY720 (fingolimod) in Multiple Sclerosis: therapeutic effects in the immune and the central nervous system

9 September 2017

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S1P3-mediated cardiac fibrosis in sphingosine kinase 1 transgenic mice involves reactive oxygen species

9 September 2017

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The SPTLC3 subunit of serine palmitoyltransferase generates short chain sphingoid bases

9 September 2017

1 reference

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Sphingosine-1-phosphate in the plasma compartment regulates basal and inflammation-induced vascular leak in mice.

9 September 2017

1 reference

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Sphingosine-1-phosphate and modulation of vascular tone

9 September 2017

1 reference

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Vascular endothelium as a contributor of plasma sphingosine 1-phosphate

9 September 2017

1 reference

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Principles of bioactive lipid signalling: lessons from sphingolipids

9 September 2017

1 reference

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Brain penetration of the oral immunomodulatory drug FTY720 and its phosphorylation in the central nervous system during experimental autoimmune encephalomyelitis: consequences for mode of action in multiple sclerosis

9 September 2017

1 reference

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The genetic dissection of essential hypertension

9 September 2017

1 reference

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Oral fingolimod (FTY720) for relapsing multiple sclerosis

9 September 2017

1 reference

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Sphingosine-1-phosphate modulates spiral modiolar artery tone: A potential role in vascular-based inner ear pathologies?

9 September 2017

1 reference

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Essential role for sphingosine kinases in neural and vascular development

9 September 2017

1 reference

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Serine palmitoyl-CoA transferase (SPT) deficiency and sphingolipid levels in mice

9 September 2017

1 reference

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Immunomodulator FTY720 Induces eNOS-dependent arterial vasodilatation via the lysophospholipid receptor S1P3.

9 September 2017

1 reference

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Structural and functional characteristics of S1P receptors.

9 September 2017

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HDL induces NO-dependent vasorelaxation via the lysophospholipid receptor S1P3.

9 September 2017

1 reference

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The immunosuppressant FTY720 is phosphorylated by sphingosine kinase type 2

9 September 2017

1 reference

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Phosphorylation of the immunomodulatory drug FTY720 by sphingosine kinases

9 September 2017

1 reference

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Phosphorylation and action of the immunomodulator FTY720 inhibits vascular endothelial cell growth factor-induced vascular permeability.

9 September 2017

1 reference

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Sphingosine kinase modulates microvascular tone and myogenic responses through activation of RhoA/Rho kinase

9 September 2017

1 reference

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Cell type-specific localization of human cardiac S1P receptors

9 September 2017

1 reference

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Ceramide kinase, a novel lipid kinase. Molecular cloning and functional characterization

9 September 2017

1 reference

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Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists

9 September 2017

1 reference

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Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation

9 September 2017

1 reference

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Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform

9 September 2017

1 reference

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Sphingosine is a novel activator of 3-phosphoinositide-dependent kinase 1.

9 September 2017

1 reference

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Signaling mechanisms underlying the vascular myogenic response

9 September 2017

1 reference

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Myogenic response gradient in an arteriolar network

9 September 2017

1 reference

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Erythropoiesis and globin gene expression in mice lacking the transcription factor NF-E2

9 September 2017

1 reference

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Removal of sphingosine 1-phosphate receptor-3 (S1P(3)) agonism is essential, but inadequate to obtain immunomodulating 2-aminopropane-1,3-diol S1P(1) agonists with reduced effect on heart rate

9 September 2017

1 reference

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Activation of sphingosine kinase by muscarinic receptors enhances NO-mediated and attenuates EDHF-mediated vasorelaxation

14 September 2017

1 reference

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S1P-lyase independent clearance of extracellular sphingosine 1-phosphate after dephosphorylation and cellular uptake

14 September 2017

1 reference

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Immunosuppressive and anti-angiogenic sphingosine 1-phosphate receptor-1 agonists induce ubiquitinylation and proteasomal degradation of the receptor

14 September 2017

1 reference

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Long-term cardiac safety and tolerability of fingolimod in multiple sclerosis: A postmarketing study.

14 September 2017

1 reference

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The immune modulator FTY720 targets sphingosine 1-phosphate receptors

25 September 2017

1 reference

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Investigating the molecular mechanisms through which FTY720-P causes persistent S1P1 receptor internalization

25 September 2017

1 reference

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FTY720 (fingolimod) increases vascular tone and blood pressure in spontaneously hypertensive rats via inhibition of sphingosine kinase

17 June 2018

1 reference

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Phase II study of oral fingolimod (FTY720) in multiple sclerosis: 3-year results

17 June 2018

1 reference

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Role of sphingosine-1-phosphate phosphohydrolase 1 in the regulation of resistance artery tone

17 June 2018

1 reference

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Deafness and stria vascularis defects in S1P2 receptor-null mice.

17 June 2018

1 reference

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Erythrocytes store and release sphingosine 1-phosphate in blood

17 June 2018

1 reference

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Interaction of sphingosine 1-phosphate with plasma components, including lipoproteins, regulates the lipid receptor-mediated actions

17 June 2018

1 reference

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Sphingosine-1-phosphate reduces rat renal and mesenteric blood flow in vivo in a pertussis toxin-sensitive manner

17 June 2018

1 reference

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Sphingosine-1-phosphate and sphingosylphosphorylcholine constrict renal and mesenteric microvessels in vitro.

17 June 2018

1 reference

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The signal modulator protein 14-3-3 is a target of sphingosine- or N,N-dimethylsphingosine-dependent kinase in 3T3(A31) cells

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4959106

Activation of casein kinase II by sphingosine.

17 June 2018

1 reference

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Fingolimod-Associated Peripheral Vascular Adverse Effects

17 June 2018

1 reference

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Role of Ca2+ -dependent and Ca2+ -sensitive mechanisms in sphingosine 1-phosphate-induced constriction of isolated porcine retinal arterioles in vitro

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4959106

Novel S1P1 receptor agonists--part 1: From pyrazoles to thiophenes.

22 August 2018

1 reference

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Inhibition of sphingosine-1-phosphate lyase rescues sphingosine kinase-1-knockout phenotype following murine cardiac arrest

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4959106

Antagonism of sphingosine 1-phosphate receptor 2 causes a selective reduction of portal vein pressure in bile duct-ligated rodents.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4959106

Sphingosine-1-phosphate-dependent activation of p38 MAPK maintains elevated peripheral resistance in heart failure through increased myogenic vasoconstriction

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4959106

Sphingosine 1-phosphate (S1P) regulates vascular contraction via S1P3 receptor: investigation based on a new S1P3 receptor antagonist

22 August 2018

1 reference

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Serine palmitoyltransferase inhibitor myriocin induces the regression of atherosclerotic plaques in hyperlipidemic ApoE-deficient mice

22 August 2018

1 reference

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A mechanistic study to assess whether isoproterenol can reverse the negative chronotropic effect of fingolimod

22 August 2018

1 reference

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Analysis of sphingosine 1-phosphate receptors involved in constriction of isolated cerebral arteries with receptor null mice and pharmacological tools

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4959106

Promotion of lymphocyte egress into blood and lymph by distinct sources of sphingosine-1-phosphate

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4959106

Sphingosine 1-phosphate is released from the cytosol of rat platelets in a carrier-mediated manner

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4959106

Essential requirement for sphingosine kinase activity in eNOS-dependent NO release and vasorelaxation.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4959106

Sphingosine kinase type 2 is essential for lymphopenia induced by the immunomodulatory drug FTY720.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4959106

Sphingosine-1-phosphate acts via rho-associated kinase and nitric oxide to regulate human placental vascular tone.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4959106

Effect of myriocin on plasma sphingolipid metabolism and atherosclerosis in apoE-deficient mice

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4959106

High-density lipoprotein stimulates myocardial perfusion in vivo.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4959106

Inhibition of sphingomyelin synthesis reduces atherogenesis in apolipoprotein E-knockout mice

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4959106

Mice deficient in sphingosine kinase 1 are rendered lymphopenic by FTY720.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4959106

Sphingosine 1-phosphate enhances portal pressure in isolated perfused liver via S1P2 with Rho activation

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4959106

Immune cell regulation and cardiovascular effects of sphingosine 1-phosphate receptor agonists in rodents are mediated via distinct receptor subtypes.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4959106

Sphingosine 1-phosphate (S1P) receptor subtypes S1P1 and S1P3, respectively, regulate lymphocyte recirculation and heart rate

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4959106

Highly effective non-viral gene transfer into vascular smooth muscle cells of cultured resistance arteries demonstrated by genetic inhibition of sphingosine-1-phosphate-induced vasoconstriction

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4959106

G-protein-coupled receptor S1P1 acts within endothelial cells to regulate vascular maturation.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4959106

S1P3 receptors mediate the potent constriction of cerebral arteries by sphingosine-1-phosphate

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4959106

Sphingosine 1-phosphate and control of vascular tone

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4959106

Effects of immunosuppressant FTY720 on renal and hepatic hemodynamics in the rat.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4959106

Comparison of sphingosine 1-phosphate-induced intracellular signaling pathways in vascular smooth muscles: differential role in vasoconstriction.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4959106

Sphingosine 1-phosphate contracts canine basilar arteries in vitro and in vivo: possible role in pathogenesis of cerebral vasospasm

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4959106

Sphingosine 1-phosphate may be a major component of plasma lipoproteins responsible for the cytoprotective actions in human umbilical vein endothelial cells

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4959106

Sphingosine 1-phosphate and activation of endothelial nitric-oxide synthase. differential regulation of Akt and MAP kinase pathways by EDG and bradykinin receptors in vascular endothelial cells

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4959106

Agonist-modulated targeting of the EDG-1 receptor to plasmalemmal caveolae. eNOS activation by sphingosine 1-phosphate and the role of caveolin-1 in sphingolipid signal transduction.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4959106

Speciation genetics: evolving approaches.

22 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1124%2FJPET.116.233205

Modulation of human arterial tone during pregnancy: the effect of the bioactive metabolite sphingosine-1-phosphate

21 January 2018

1 reference

12 December 2020

Sphingosine 1-phosphate induces platelet activation through an extracellular action and shares a platelet surface receptor with lysophosphatidic acid

1 reference

12 December 2020

On the local reactions of the arterial wall to changes of internal pressure

1 reference

12 December 2020

Effects of sphingosine 1-phosphate, a naturally occurring biologically active lysophospholipid, on the rat cardiovascular system

1 reference

12 December 2020

FTY720: placebo-controlled study of the effect on cardiac rate and rhythm in healthy subjects

1 reference

12 December 2020

Vascular dysfunction in S1P2 sphingosine 1-phosphate receptor knockout mice

1 reference

12 December 2020

Sphingosine 1-phosphate, a bioactive sphingolipid abundantly stored in platelets, is a normal constituent of human plasma and serum

1 reference

12 December 2020

Effect of chemically well-defined sphingosine and its N-methyl derivatives on protein kinase C and src kinase activities

1 reference

12 December 2020

The sphingosine kinase-sphingosine-1-phosphate axis is a determinant of mast cell function and anaphylaxis

1 reference

12 December 2020

Identifiers

DOI

10.1124/JPET.116.233205

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27317800%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27317800%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

PubMed publication ID

27317800

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27317800%20AND%20SRC:MED&resulttype=core&format=json