The lymphatic vasculature: development and role in shaping immunity. (Q38810930)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27088921%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

title

The lymphatic vasculature: development and role in shaping immunity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27088921%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27088921%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27088921%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Kelly L Betterman

1 reference

6 September 2017

Natasha L Harvey

series ordinal

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6 September 2017

publication date

1 May 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27088921%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

published in

Immunological Reviews

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27088921%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

volume

271

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27088921%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

issue

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27088921%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

page(s)

276-292

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27088921%20AND%20SRC:MED&resulttype=core&format=json

Lymphatic vascular morphogenesis in development, physiology, and disease

2 April 2020

cites work

1 reference

Morphogenesis of the lymphatic vasculature: A focus on new progenitors and cellular mechanisms important for constructing lymphatic vessels

21 January 2018

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Lymphangiogenesis: Molecular mechanisms and future promise

21 January 2018

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Ultrastructural studies on the lymphatic anchoring filaments

21 January 2018

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Functionally specialized junctions between endothelial cells of lymphatic vessels

21 January 2018

1 reference

Getting out and about: the emergence and morphogenesis of the vertebrate lymphatic vasculature.

21 January 2018

1 reference

Physiologic aspects of lymphatic contractile function: current perspectives

21 January 2018

1 reference

Emerging roles of lymphatic endothelium in regulating adaptive immunity

21 January 2018

1 reference

The link between lymphatic function and adipose biology.

21 January 2018

1 reference

In vivo evidence for the involvement of the adipose tissue surrounding lymph nodes in immune responses

21 January 2018

1 reference

An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells

21 January 2018

1 reference

From sewer to saviour - targeting the lymphatic system to promote drug exposure and activity.

21 January 2018

1 reference

Intravital imaging of intestinal lacteals unveils lipid drainage through contractility

21 January 2018

1 reference

Lymphatic vessels are essential for the removal of cholesterol from peripheral tissues by SR-BI-mediated transport of HDL.

21 January 2018

1 reference

Lymphatic vasculature mediates macrophage reverse cholesterol transport in mice

21 January 2018

1 reference

Lymphatic vascular defects promoted by Prox1 haploinsufficiency cause adult-onset obesity

21 January 2018

1 reference

An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype

21 January 2018

1 reference

Lineage tracing demonstrates the venous origin of the mammalian lymphatic vasculature

21 January 2018

1 reference

Live imaging of lymphatic development in the zebrafish

21 January 2018

1 reference

Vegfc Regulates Bipotential Precursor Division and Prox1 Expression to Promote Lymphatic Identity in Zebrafish.

21 January 2018

1 reference

Segmental territories along the cardinal veins generate lymph sacs via a ballooning mechanism during embryonic lymphangiogenesis in mice

21 January 2018

1 reference

Lymphatic endothelial progenitors bud from the cardinal vein and intersomitic vessels in mammalian embryos

21 January 2018

1 reference

A novel multistep mechanism for initial lymphangiogenesis in mouse embryos based on ultramicroscopy

21 January 2018

1 reference

Sox18 induces development of the lymphatic vasculature in mice

21 January 2018

1 reference

The nuclear hormone receptor Coup-TFII is required for the initiation and early maintenance of Prox1 expression in lymphatic endothelial cells.

21 January 2018

1 reference

Control of retinoid levels by CYP26B1 is important for lymphatic vascular development in the mouse embryo

21 January 2018

1 reference

Decoy receptor CXCR7 modulates adrenomedullin-mediated cardiac and lymphatic vascular development

21 January 2018

1 reference

Notch1 functions as a negative regulator of lymphatic endothelial cell differentiation in the venous endothelium

21 January 2018

1 reference

Bone morphogenetic protein 2 signaling negatively modulates lymphatic development in vertebrate embryos

21 January 2018

1 reference

Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins

21 January 2018

1 reference

Vascular endothelial growth factor D is dispensable for development of the lymphatic system

21 January 2018

1 reference

Vegfd can compensate for loss of Vegfc in zebrafish facial lymphatic sprouting

21 January 2018

1 reference

VEGFR-3 ligand-binding and kinase activity are required for lymphangiogenesis but not for angiogenesis

21 January 2018

1 reference

Ccbe1 is required for embryonic lymphangiogenesis and venous sprouting

21 January 2018

1 reference

Mutations in CCBE1 cause generalized lymph vessel dysplasia in humans

21 January 2018

1 reference

CCBE1 Is Essential for Mammalian Lymphatic Vascular Development and Enhances the Lymphangiogenic Effect of Vascular Endothelial Growth Factor-C In Vivo

21 January 2018

1 reference

Ccbe1 regulates Vegfc-mediated induction of Vegfr3 signaling during embryonic lymphangiogenesis

21 January 2018

1 reference

CCBE1 enhances lymphangiogenesis via A disintegrin and metalloprotease with thrombospondin motifs-3-mediated vascular endothelial growth factor-C activation

21 January 2018

1 reference

Nonvenous origin of dermal lymphatic vasculature

21 January 2018

1 reference

Cardiac lymphatics are heterogeneous in origin and respond to injury.

21 January 2018

1 reference

The left-right Pitx2 pathway drives organ-specific arterial and lymphatic development in the intestine

21 January 2018

1 reference

Lymphatic vessels arise from specialized angioblasts within a venous niche.

21 January 2018

1 reference

Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation

21 January 2018

1 reference

Prox1 dosage controls the number of lymphatic endothelial cell progenitors and the formation of the lymphovenous valves

21 January 2018

1 reference

Multiple mouse models of primary lymphedema exhibit distinct defects in lymphovenous valve development

21 January 2018

1 reference

Integrin-α5β1 is not required for mural cell functions during development of blood vessels but is required for lymphatic-blood vessel separation and lymphovenous valve formation

21 January 2018

1 reference

Platelets mediate lymphovenous hemostasis to maintain blood-lymphatic separation throughout life.

21 January 2018

1 reference

Regulation of blood and lymphatic vascular separation by signaling proteins SLP-76 and Syk.

21 January 2018

1 reference

Platelets regulate lymphatic vascular development through CLEC-2-SLP-76 signaling

21 January 2018

1 reference

Platelets play an essential role in separating the blood and lymphatic vasculatures during embryonic angiogenesis

21 January 2018

1 reference

Essential in vivo roles of the C-type lectin receptor CLEC-2: embryonic/neonatal lethality of CLEC-2-deficient mice by blood/lymphatic misconnections and impaired thrombus formation of CLEC-2-deficient platelets.

21 January 2018

1 reference

Novel function for blood platelets and podoplanin in developmental separation of blood and lymphatic circulation.

21 January 2018

1 reference

Postnatal lymphatic partitioning from the blood vasculature in the small intestine requires fasting-induced adipose factor

21 January 2018

1 reference

PDZ interaction site in ephrinB2 is required for the remodeling of lymphatic vasculature

21 January 2018

1 reference

EphB4 forward signalling regulates lymphatic valve development

21 January 2018

1 reference

Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by Angiopoietin-1.

21 January 2018

1 reference

Defective remodeling and maturation of the lymphatic vasculature in Angiopoietin-2 deficient mice.

21 January 2018

1 reference

Loss of endothelial Tie1 receptor impairs lymphatic vessel development-brief report

21 January 2018

1 reference

Abnormal embryonic lymphatic vessel development in Tie1 hypomorphic mice

21 January 2018

1 reference

Smooth muscle-endothelial cell communication activates Reelin signaling and regulates lymphatic vessel formation

21 January 2018

1 reference

Semaphorin3A, Neuropilin-1, and PlexinA1 are required for lymphatic valve formation

21 January 2018

1 reference

An unexpected role of semaphorin3a-neuropilin-1 signaling in lymphatic vessel maturation and valve formation.

21 January 2018

1 reference

Genes regulating lymphangiogenesis control venous valve formation and maintenance in mice

21 January 2018

1 reference

Absence of venous valves in mice lacking Connexin37

21 January 2018

1 reference

Planar cell polarity protein Celsr1 regulates endothelial adherens junctions and directed cell rearrangements during valve morphogenesis

21 January 2018

1 reference

Integrin-alpha9 is required for fibronectin matrix assembly during lymphatic valve morphogenesis

21 January 2018

1 reference

Mechanotransduction, PROX1, and FOXC2 cooperate to control connexin37 and calcineurin during lymphatic-valve formation

21 January 2018

1 reference

Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasis

21 January 2018

1 reference

FOXC2 controls formation and maturation of lymphatic collecting vessels through cooperation with NFATc1

21 January 2018

1 reference

Blood flow reprograms lymphatic vessels to blood vessels

21 January 2018

1 reference

Connexin37 and Connexin43 deficiencies in mice disrupt lymphatic valve development and result in lymphatic disorders including lymphedema and chylothorax

21 January 2018

1 reference

GATA2 is required for lymphatic vessel valve development and maintenance.

21 January 2018

1 reference

Lymph flow regulates collecting lymphatic vessel maturation in vivo.

21 January 2018

1 reference

Bone morphogenetic protein 9 (BMP9) controls lymphatic vessel maturation and valve formation

21 January 2018

1 reference

Notch signaling functions in lymphatic valve formation

21 January 2018

1 reference

Inflammation-induced lymphangiogenesis in the cornea arises from CD11b-positive macrophages

21 January 2018

1 reference

Lymphatic endothelial progenitor cells contribute to de novo lymphangiogenesis in human renal transplants.

21 January 2018

1 reference

M-CSF inhibition selectively targets pathological angiogenesis and lymphangiogenesis

21 January 2018

1 reference

Regulation of developmental lymphangiogenesis by Syk(+) leukocytes

21 January 2018

1 reference

Deciphering the roles of macrophages in developmental and inflammation stimulated lymphangiogenesis

21 January 2018

1 reference

Inflammation-associated lymphangiogenesis: a double-edged sword?

21 January 2018

1 reference

New insights into the development of lymphoid tissues

21 January 2018

1 reference

Lymph sacs are not required for the initiation of lymph node formation

21 January 2018

1 reference

Isolation and characterization of dermal lymphatic and blood endothelial cells reveal stable and functionally specialized cell lineages

21 January 2018

1 reference

Coexpression of the chemokines ELC and SLC by T zone stromal cells and deletion of the ELC gene in the plt/plt mouse

21 January 2018

1 reference

HEVs, lymphatics and homeostatic immune cell trafficking in lymph nodes

21 January 2018

1 reference

B cell-driven lymphangiogenesis in inflamed lymph nodes enhances dendritic cell mobilization

21 January 2018

1 reference

Sphingosine-1-phosphate and lymphocyte egress from lymphoid organs

21 January 2018

1 reference

Preformed portals facilitate dendritic cell entry into afferent lymphatic vessels

21 January 2018

1 reference

Interstitial dendritic cell guidance by haptotactic chemokine gradients

21 January 2018

1 reference

Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning

21 January 2018

1 reference

Lymphocyte sequestration through S1P lyase inhibition and disruption of S1P gradients

21 January 2018

1 reference

Semaphorins guide the entry of dendritic cells into the lymphatics by activating myosin II

21 January 2018

1 reference

An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium

21 January 2018

1 reference

Transmural flow modulates cell and fluid transport functions of lymphatic endothelium

21 January 2018

1 reference

CLEVER-1 mediates lymphocyte transmigration through vascular and lymphatic endothelium

21 January 2018

1 reference

The chemokine CX3CL1 promotes trafficking of dendritic cells through inflamed lymphatics

21 January 2018

1 reference

VEGF-D promotes tumor metastasis by regulating prostaglandins produced by the collecting lymphatic endothelium

21 January 2018

1 reference

Neutrophils rapidly migrate via lymphatics after Mycobacterium bovis BCG intradermal vaccination and shuttle live bacilli to the draining lymph nodes

21 January 2018

1 reference

Dynamics of neutrophil migration in lymph nodes during infection

21 January 2018

1 reference

Microbe-dependent lymphatic migration of neutrophils modulates lymphocyte proliferation in lymph nodes

21 January 2018

1 reference

Conditional ablation of LYVE-1+ cells unveils defensive roles of lymphatic vessels in intestine and lymph nodes

21 January 2018

1 reference

Lymph node-resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation

21 January 2018

1 reference

Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells

21 January 2018

1 reference

Endothelial nitric oxide synthase regulates microlymphatic flow via collecting lymphatics

21 January 2018

1 reference

Mechanobiological oscillators control lymph flow

21 January 2018

1 reference

Clinical disorders of primary malfunctioning of the lymphatic system

21 January 2018

1 reference

New developments in clinical aspects of lymphatic disease

21 January 2018

1 reference

Mutations in the transcription factor gene SOX18 underlie recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia

21 January 2018

1 reference

Truncating mutations in FOXC2 cause multiple lymphedema syndromes

21 January 2018

1 reference

Analysis of the phenotypic abnormalities in lymphoedema-distichiasis syndrome in 74 patients with FOXC2 mutations or linkage to 16q24

21 January 2018

1 reference

Mutations in GATA2 cause primary lymphedema associated with a predisposition to acute myeloid leukemia (Emberger syndrome)

21 January 2018

1 reference

Loss-of-function germline GATA2 mutations in patients with MDS/AML or MonoMAC syndrome and primary lymphedema reveal a key role for GATA2 in the lymphatic vasculature

21 January 2018

1 reference

X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-kappaB signaling

21 January 2018

1 reference

GJC2 missense mutations cause human lymphedema

21 January 2018

1 reference

Rapid identification of mutations in GJC2 in primary lymphoedema using whole exome sequencing combined with linkage analysis with delineation of the phenotype

21 January 2018

1 reference

A novel mutation in GJA1 causing oculodentodigital syndrome and primary lymphoedema in a three generation family.

21 January 2018

1 reference

Connexin 47 mutations increase risk for secondary lymphedema following breast cancer treatment

21 January 2018

1 reference

Fatal bilateral chylothorax in mice lacking the integrin alpha9beta1.

21 January 2018

1 reference

A recurrent ITGA9 missense mutation in human fetuses with severe chylothorax: possible correlation with poor response to fetal therapy

21 January 2018

1 reference

Hereditary lymphedema: evidence for linkage and genetic heterogeneity

21 January 2018

1 reference

Congenital hereditary lymphedema caused by a mutation that inactivates VEGFR3 tyrosine kinase

21 January 2018

1 reference

Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema

21 January 2018

1 reference

Mutation in vascular endothelial growth factor-C, a ligand for vascular endothelial growth factor receptor-3, is associated with autosomal dominant milroy-like primary lymphedema.

21 January 2018

1 reference

A novel stop mutation in the vascular endothelial growth factor-C gene (VEGFC) results in Milroy-like disease

21 January 2018

1 reference

Linkage and sequence analysis indicate that CCBE1 is mutated in recessively inherited generalised lymphatic dysplasia.

21 January 2018

1 reference

Hennekam syndrome can be caused by FAT4 mutations and be allelic to Van Maldergem syndrome

21 January 2018

1 reference

Protein tyrosine phosphatase PTPN14 is a regulator of lymphatic function and choanal development in humans

21 January 2018

1 reference

Mutations in the VEGFR3 signaling pathway explain 36% of familial lymphedema

21 January 2018

1 reference

Mutations in KIF11 cause autosomal-dominant microcephaly variably associated with congenital lymphedema and chorioretinopathy

21 January 2018

1 reference

Novel mutations in PIEZO1 cause an autosomal recessive generalized lymphatic dysplasia with non-immune hydrops fetalis

21 January 2018

1 reference

Piezo1 integration of vascular architecture with physiological force.

21 January 2018

1 reference

Piezo1, a mechanically activated ion channel, is required for vascular development in mice.

21 January 2018

1 reference

Genetics of lymphatic anomalies

21 January 2018

1 reference

Noonan syndrome: clinical aspects and molecular pathogenesis

21 January 2018

1 reference

Germline KRAS mutations cause Noonan syndrome

21 January 2018

1 reference

RASA1 mutations and associated phenotypes in 68 families with capillary malformation-arteriovenous malformation

21 January 2018

1 reference

Lymphangioleiomyomatosis - a wolf in sheep's clothing.

21 January 2018

1 reference

Critical role of CD11b+ macrophages and VEGF in inflammatory lymphangiogenesis, antigen clearance, and inflammation resolution

21 January 2018

1 reference

Role of CD11b+ macrophages in intraperitoneal lipopolysaccharide-induced aberrant lymphangiogenesis and lymphatic function in the diaphragm

21 January 2018

1 reference

Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation.

21 January 2018

1 reference

An important role of lymphatic vessel activation in limiting acute inflammation

21 January 2018

1 reference

Cutting edge: lymphatic vessels, not blood vessels, primarily mediate immune rejections after transplantation

21 January 2018

1 reference

Targeting lymphatic vessel activation and CCL21 production by vascular endothelial growth factor receptor-3 inhibition has novel immunomodulatory and antiarteriosclerotic effects in cardiac allografts.

21 January 2018

1 reference

Role of the lymphatic system in the pathogenesis of Crohn's disease

21 January 2018

1 reference

Lymphatic vascular integrity is disrupted in type 2 diabetes due to impaired nitric oxide signalling

21 January 2018

1 reference

Lymphatic function is required prenatally for lung inflation at birth.

21 January 2018

1 reference

Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism

21 January 2018

1 reference

Immune cells control skin lymphatic electrolyte homeostasis and blood pressure

21 January 2018

1 reference

Preexisting Lymphatic Endothelium but not Endothelial Progenitor Cells Are Essential for Tumor Lymphangiogenesis and Lymphatic Metastasis

21 January 2018

1 reference

Mcl-1 and Bcl-xL coordinately regulate megakaryocyte survival

21 January 2018

1 reference

T Lymphocytes Negatively Regulate Lymph Node Lymphatic Vessel Formation

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/IMR.12413

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27088921%20AND%20SRC:MED&resulttype=core&format=json

release_zosplfr4nncz7or7rzwclakvye

2 April 2020

Fatcat ID

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24 November 2022

based on heuristic

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