Reduced chondrogenic matrix accumulation by 4-methylumbelliferone reveals the potential for selective targeting of UDP-glucose dehydrogenase (Q38810044)

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scientific article published on February 1, 2011

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English	Reduced chondrogenic matrix accumulation by 4-methylumbelliferone reveals the potential for selective targeting of UDP-glucose dehydrogenase	scientific article published on February 1, 2011

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

6 September 2017

Reduced chondrogenic matrix accumulation by 4-methylumbelliferone reveals the potential for selective targeting of UDP-glucose dehydrogenase (English)

1 reference

Europe PubMed Central

PMC publication ID

6 September 2017

author name string

C. E. Clarkin

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21292001

23 November 2024

S. Allen

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21292001

23 November 2024

C. P. Wheeler-Jones

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21292001

23 November 2024

E. R. Bastow

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21292001

23 November 2024

A. A. Pitsillides

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21292001

23 November 2024

language of work or name

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21292001

23 November 2024

publication date

1 February 2011

1 reference

Europe PubMed Central

PMC publication ID

6 September 2017

full work available at URL

https://doi.org/10.1016/j.matbio.2011.01.002

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21292001

23 November 2024

https://europepmc.org/articles/PMC3200435

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21292001

23 November 2024

https://api.elsevier.com/content/article/PII:S0945053X11000060?httpAccept=text/xml

1 reference

10.1016/J.MATBIO.2011.01.002

https://api.crossref.org/works/10.1016/J.MATBIO.2011.01.002

23 November 2024

https://api.elsevier.com/content/article/PII:S0945053X11000060?httpAccept=text/plain

1 reference

10.1016/J.MATBIO.2011.01.002

https://api.crossref.org/works/10.1016/J.MATBIO.2011.01.002

23 November 2024

1 reference

Europe PubMed Central

PMC publication ID

6 September 2017

30

1 reference

Europe PubMed Central

PMC publication ID

6 September 2017

3

1 reference

Europe PubMed Central

PMC publication ID

6 September 2017

163-168

1 reference

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6 September 2017

A hyaluronan synthase suppressor, 4-methylumbelliferone, inhibits liver metastasis of melanoma cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200435

9 September 2017

A novel mechanism for the inhibition of hyaluronan biosynthesis by 4-methylumbelliferone

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200435

9 September 2017

Age-related changes in the response of human articular cartilage to IL-1alpha and transforming growth factor-beta (TGF-beta): chondrocytes exhibit a diminished sensitivity to TGF-beta.

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Identifying and characterizing the joint cavity-forming cell

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Hyaluronan synthase elevation in metastatic prostate carcinoma cells correlates with hyaluronan surface retention, a prerequisite for rapid adhesion to bone marrow endothelial cells

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9 September 2017

Antitumor activity of hyaluronic acid synthesis inhibitor 4-methylumbelliferone in prostate cancer cells

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14 September 2017

4-Methylumbelliferone inhibits hyaluronan synthesis by depletion of cellular UDP-glucuronic acid and downregulation of hyaluronan synthase 2 and 3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200435

14 September 2017

Study of hyaluronan synthase inhibitor, 4-methylumbelliferone derivatives on human pancreatic cancer cell (KP1-NL).

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14 September 2017

A specific mechanomodulatory role for p38 MAPK in embryonic joint articular surface cell MEK-ERK pathway regulation

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22 June 2018

Molecular cloning and characterization of UDP-glucose dehydrogenase from the amphibian Xenopus laevis and its involvement in hyaluronan synthesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200435

22 June 2018

Sulfate activation and transport in mammals: system components and mechanisms

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22 June 2018

Subcellular localization of hyaluronate synthetase in oligodendroglioma cells.

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22 June 2018

Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue

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22 June 2018

Regulation of UDP-glucose dehydrogenase is sufficient to modulate hyaluronan production and release, control sulfated GAG synthesis, and promote chondrogenesis.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200435

31 August 2018

Stimulation of small proteoglycan synthesis by the hyaluronan synthesis inhibitor 4-methylumbelliferone in human skin fibroblasts.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200435

31 August 2018

The effects of 4-methylumbelliferone on hyaluronan synthesis, MMP2 activity, proliferation, and motility of human aortic smooth muscle cells.

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31 August 2018

Differential regulation of GDF-5 and FGF-2/4 by immobilisation in ovo exposes distinct roles in joint formation

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31 August 2018

4-methylumbelliferone, a hyaluronan synthase suppressor, enhances the anticancer activity of gemcitabine in human pancreatic cancer cells

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31 August 2018

Selective activation of the MEK-ERK pathway is regulated by mechanical stimuli in forming joints and promotes pericellular matrix formation

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31 August 2018

Essential role of glycosaminoglycans in Fgf signaling during mouse gastrulation.

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Caenorhabditis elegans early embryogenesis and vulval morphogenesis require chondroitin biosynthesis

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Biosynthesis of proteoglycan in bone and cartilage of parathyroid hormone-related protein knockout mice.

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Measurement of serum hyaluronic acid in patients with chronic hepatitis C and its relationship to liver histology. Consensus Interferon Study Group

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Ectopic expression of Msx-2 in posterior limb bud mesoderm impairs limb morphogenesis while inducing BMP-4 expression, inhibiting cell proliferation, and promoting apoptosis.

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31 August 2018

Dlx5 is a positive regulator of chondrocyte differentiation during endochondral ossification

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12 December 2020

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An ELISA plate-based assay for hyaluronan using biotinylated proteoglycan G1 domain (HA-binding region)

1 reference

https://pubmed.ncbi.nlm.nih.gov/21292001

12 December 2020

based on heuristic

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Hyaluronic-Acid-Deficient Extracellular Matrix Induced by Addition of 4-Methylumbelliferone to the Medium of Cultured Human Skin Fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/21292001

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of 4‐methylumbelliferone on cell‐free synthesis of hyaluronic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/21292001

12 December 2020

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inferred from PubMed ID database lookup

Heparan sulfate proteoglycans including syndecan-3 modulate BMP activity during limb cartilage differentiation

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https://pubmed.ncbi.nlm.nih.gov/21292001

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Regulation of hyaluronan synthesis by vasodilatory prostaglandins. Implications for atherosclerosis

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https://pubmed.ncbi.nlm.nih.gov/21292001

12 December 2020

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inferred from PubMed ID database lookup

Identifiers

10.1016/J.MATBIO.2011.01.002

1 reference

Europe PubMed Central

PMC publication ID

6 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

6 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

6 September 2017

ResearchGate publication ID

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