Astroglial Scarring and Seizures: A Cell Biological Perspective on Epilepsy (Q38818777)

6 September 2017

title

Astroglial Scarring and Seizures: A Cell Biological Perspective on Epilepsy (English)

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6 September 2017

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Stefanie Robel

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6 September 2017

publication date

26 April 2016

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6 September 2017

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Mislocalization of AQP4 precedes chronic seizures in the kainate model of temporal lobe epilepsy

6 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

The molecular basis of water transport in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Astrocyte scar formation aids central nervous system axon regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Glial and neuronal control of brain blood flow

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Live imaging of astrocyte responses to acute injury reveals selective juxtavascular proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Astrocyte development and heterogeneity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Astrocyte calcium signaling: the third wave

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Altered Kir and gap junction channels in temporal lobe epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Dynamic changes in myelin aberrations and oligodendrocyte generation in chronic amyloidosis in mice and men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Effects of sleep and wake on astrocytes: clues from molecular and ultrastructural studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Refuting the challenges of the developmental shift of polarity of GABA actions: GABA more exciting than ever!

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Design and initial results of a multi-phase randomized trial of ceftriaxone in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Glial cells as primary therapeutic targets for epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

21 January 2018

Aquaporin-4 and epilepsy

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Epilepsy, ataxia, sensorineural deafness, tubulopathy, and KCNJ10 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Assembly of a perivascular astrocyte protein scaffold at the mammalian blood-brain barrier is dependent on alpha-syntrophin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Disease-modifying effects of phenobarbital and the NKCC1 inhibitor bumetanide in the pilocarpine model of temporal lobe epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Role of glial K(+) channels in ontogeny and gliosis: a hypothesis based upon studies on Müller cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Müller glial cells in retinal disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Glutamate and tumor-associated epilepsy: glial cell dysfunction in the peritumoral environment

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Origin and progeny of reactive gliosis: A source of multipotent cells in the injured brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

The role of extracellular matrix in CNS regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Leukocyte infiltration, neuronal degeneration, and neurite outgrowth after ablation of scar-forming, reactive astrocytes in adult transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Functional changes in glutamate transporters and astrocyte biophysical properties in a rodent model of focal cortical dysplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Enhanced asynchronous Ca(2+) oscillations associated with impaired glutamate transport in cortical astrocytes expressing Fmr1 gene premutation expansion

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Growth-associated gene expression after stroke: evidence for a growth-promoting region in peri-infarct cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Implication of Kir4.1 channel in excess potassium clearance: an in vivo study on anesthetized glial-conditional Kir4.1 knock-out mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Safety and efficacy of ceftriaxone for amyotrophic lateral sclerosis: a multi-stage, randomised, double-blind, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Targeted inactivation of dystrophin gene product Dp71: phenotypic impact in mouse retina

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Metabotropic P2Y1 receptor signalling mediates astrocytic hyperactivity in vivo in an Alzheimer's disease mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Extracellular matrix in plasticity and epileptogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Conditional knock-out of Kir4.1 leads to glial membrane depolarization, inhibition of potassium and glutamate uptake, and enhanced short-term synaptic potentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Loss of perivascular aquaporin 4 may underlie deficient water and K+ homeostasis in the human epileptogenic hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Transplanted glioma cells migrate and proliferate on host brain vasculature: a dynamic analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Fine mapping of a seizure susceptibility locus on mouse Chromosome 1: nomination of Kcnj10 as a causative gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

CNS injury, glial scars, and inflammation: Inhibitory extracellular matrices and regeneration failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Kir4.1 and AQP4 associate with Dp71- and utrophin-DAPs complexes in specific and defined microdomains of Müller retinal glial cell membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Specification and Morphogenesis of Astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Long-lasting pro-ictogenic effects induced in vivo by rat brain exposure to serum albumin in the absence of concomitant pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Extracellular matrix regulation of inflammation in the healthy and injured spinal cord

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Response to comments on "Local impermeant anions establish the neuronal chloride concentration".

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Local impermeant anions establish the neuronal chloride concentration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Brain metabolism dictates the polarity of astrocyte control over arterioles

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Status epilepticus, blood-brain barrier disruption, inflammation, and epileptogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Early down regulation of the glial Kir4.1 and GLT-1 expression in pericontusional cortex of the old male mice subjected to traumatic brain injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Evidence that compromised K+ spatial buffering contributes to the epileptogenic effect of mutations in the human Kir4.1 gene (KCNJ10).

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Brain glutamate transporter proteins form homomultimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Blood-brain barrier dysfunction, TGFβ signaling, and astrocyte dysfunction in epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

A possible role of dystrophin in neuronal excitability: a review of the current literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Loss of perivascular Kir4.1 potassium channels in the sclerotic hippocampus of patients with mesial temporal lobe epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Role of Kir4.1 channels in growth control of glia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Recent developments in the understanding of astrocyte function in the cerebellum in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Glial regulation of the cerebral microvasculature

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

The pathobiology of vascular dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Impairment of glymphatic pathway function promotes tau pathology after traumatic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Brain-wide pathway for waste clearance captured by contrast-enhanced MRI

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

TGF-beta receptor-mediated albumin uptake into astrocytes is involved in neocortical epileptogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Transforming growth factor β-induced expression of chondroitin sulfate proteoglycans is mediated through non-Smad signaling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Are you in or out? Leukocyte, ion, and neurotransmitter permeability across the epileptic blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Astrocyte contributions to flow/pressure-evoked parenchymal arteriole vasoconstriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Long-term changes in expressions of spinal glutamate transporters after spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Vascular amyloidosis impairs the gliovascular unit in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Endogenous nitric oxide is a key promoting factor for initiation of seizure-like events in hippocampal and entorhinal cortex slices.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Impairment of paravascular clearance pathways in the aging brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Early identification of refractory epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Neural progenitor cells regulate capillary blood flow in the postnatal subventricular zone

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Decreased expression of the glial water channel aquaporin-4 in the intrahippocampal kainic acid model of epileptogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

GFAP-expressing cells in the postnatal subventricular zone display a unique glial phenotype intermediate between radial glia and astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Traumatic brain injury and epilepsy: Underlying mechanisms leading to seizure

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Comment on "Local impermeant anions establish the neuronal chloride concentration".

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Dynamic neurovascular coupling and uncoupling during ictal onset, propagation, and termination revealed by simultaneous in vivo optical imaging of neural activity and local blood volume

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Vascular β-amyloid and early astrocyte alterations impair cerebrovascular function and cerebral metabolism in transgenic arcAβ mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Elevated GFAP induces astrocyte dysfunction in caudal brain regions: A potential mechanism for hindbrain involved symptoms in type II Alexander disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Persistent cortical plasticity by upregulation of chondroitin 6-sulfation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Ordered disorder of the astrocytic dystrophin-associated protein complex in the norm and pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Glial cell regulation of neuronal activity and blood flow in the retina by release of gliotransmitters

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Upregulation of GLT-1 by treatment with ceftriaxone alleviates radicular pain by reducing spinal astrocyte activation and neuronal hyperexcitability

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Direct astrocytic contacts regulate local maturation of dendritic spines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Agrin defines polarized distribution of orthogonal arrays of particles in astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

DNA methylation functions as a critical regulator of Kir4.1 expression during CNS development

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Uniquely hominid features of adult human astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Loss of astrocytic domain organization in the epileptic brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Development, maintenance and disruption of the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Spinal cord injury causes a wide-spread, persistent loss of Kir4.1 and glutamate transporter 1: benefit of 17 beta-oestradiol treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Differential distribution of Kir4.1 in spinal cord astrocytes suggests regional differences in K+ homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

New Insights on Astrocyte Ion Channels: Critical for Homeostasis and Neuron-Glia Signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Functional implications for Kir4.1 channels in glial biology: from K+ buffering to cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Selective induction of astrocytic gliosis generates deficits in neuronal inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Epileptic focus and alteration of metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Astrocyte Ca2+ Signaling Drives Inversion of Neurovascular Coupling after Subarachnoid Hemorrhage

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Tripartite synapses: astrocytes process and control synaptic information

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

KCNJ10 gene mutations causing EAST syndrome (epilepsy, ataxia, sensorineural deafness, and tubulopathy) disrupt channel function

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Neurodevelopmental, emotional, and behavioural problems in Duchenne muscular dystrophy in relation to underlying dystrophin gene mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Genetic deletion of cdc42 reveals a crucial role for astrocyte recruitment to the injury site in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

The stem cell potential of glia: lessons from reactive gliosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Reactive astrogliosis causes the development of spontaneous seizures

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Conditional deletion of beta1-integrin in astroglia causes partial reactive gliosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Glia as drivers of abnormal neuronal activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Tonic Local Brain Blood Flow Control by Astrocytes Independent of Phasic Neurovascular Coupling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Beta-lactam antibiotics offer neuroprotection by increasing glutamate transporter expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Selective loss of glial glutamate transporter GLT‐1 in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Matrix metalloproteinase inhibition in atherosclerosis and stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Visualizing spatiotemporal dynamics of multicellular cell-cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Fibrinogen triggers astrocyte scar formation by promoting the availability of active TGF-beta after vascular damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Functional and molecular properties of human astrocytes in acute hippocampal slices obtained from patients with temporal lobe epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Analysis of astroglial K+ channel expression in the developing hippocampus reveals a predominant role of the Kir4.1 subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Lasting blood-brain barrier disruption induces epileptic focus in the rat somatosensory cortex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Reactive glia in the injured brain acquire stem cell properties in response to sonic hedgehog. [corrected].

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Focal laser-lesions activate an endogenous population of neural stem/progenitor cells in the adult visual cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Molecular dissection of reactive astrogliosis and glial scar formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Astrocytes: biology and pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Targeting the neural extracellular matrix in neurological disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

GLT-1 transporter: an effective pharmacological target for various neurological disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Two-photon imaging of astrocytic Ca2+ signaling and the microvasculature in experimental mice models of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

General anesthesia selectively disrupts astrocyte calcium signaling in the awake mouse cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Astrocyte-specific TSC1 conditional knockout mice exhibit abnormal neuronal organization and seizures

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Decreased expression of glutamate transporters in astrocytes after human traumatic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Redistribution of the water channel protein aquaporin-4 and the K+ channel protein Kir4.1 differs in low- and high-grade human brain tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Disruption of astrocyte-vascular coupling and the blood-brain barrier by invading glioma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Glycogen synthase kinase 3 beta regulates glial glutamate transporter protein expression in the spinal dorsal horn in rats with neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Vascular amyloid alters astrocytic water and potassium channels in mouse models and humans with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Agrin, aquaporin-4, and astrocyte polarity as an important feature of the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Impaired glial glutamate transport in a mouse tuberous sclerosis epilepsy model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Sleep drives metabolite clearance from the adult brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Laminin isoforms in endothelial and perivascular basement membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Genomic analysis of reactive astrogliosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

The disruption of central CO2 chemosensitivity in a mouse model of Rett syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

Focal increases in perfusion and decreases in hemoglobin oxygenation precede seizure onset in spontaneous human epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416645498

21 January 2018

Identifiers

DOI

10.1177/1073858416645498

0 references

1 reference