Beta-cell specific autoantibodies: Are they just an indicator of type 1 diabetes? (Q38818303)

7 June 2018

title

Beta-cell specific autoantibodies: Are they just an indicator of type 1 diabetes? (English)

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7 June 2018

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7 June 2018

author name string

Elio Ippolito

series ordinal

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7 June 2018

Rizwan Ahmed

series ordinal

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7 June 2018

Abdel Rahim A Hamad

series ordinal

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7 June 2018

publication date

1 January 2017

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7 June 2018

published in

Current Diabetes Reviews

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7 June 2018

volume

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7 June 2018

issue

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7 June 2018

page(s)

322-329

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7 June 2018

Antigen-Specific Regulatory T Cells and Low Dose of IL-2 in Treatment of Type 1 Diabetes

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17 June 2018

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17 June 2018

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Restoration of the unfolded protein response in pancreatic β cells protects mice against type 1 diabetes

17 June 2018

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Infectious triggers in type 1 diabetes: is there a case for epitope mimicry?

17 June 2018

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17 June 2018

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17 June 2018

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Seroconversion to multiple islet autoantibodies and risk of progression to diabetes in children

17 June 2018

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Antidiabetogenic MHC class II promotes the differentiation of MHC-promiscuous autoreactive T cells into FOXP3+ regulatory T cells

17 June 2018

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Pathogenesis of type 1 diabetes: lessons from natural history studies of high-risk individuals

17 June 2018

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Do MHCII-presented neoantigens drive type 1 diabetes and other autoimmune diseases?

17 June 2018

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Infection as a cause of type 1 diabetes?

17 June 2018

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Following the fate of one insulin-reactive CD4 T cell: conversion into Teffs and Tregs in the periphery controls diabetes in NOD mice

17 June 2018

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Breakdown in peripheral tolerance in type 1 diabetes in mice and humans

17 June 2018

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17 June 2018

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Reduced prevalence of diabetic ketoacidosis at diagnosis of type 1 diabetes in young children participating in longitudinal follow-up

17 June 2018

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17 June 2018

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Rituximab Selectively Suppresses Specific Islet Antibodies

17 June 2018

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The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans

17 June 2018

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Anti-islet autoantibodies trigger autoimmune diabetes in the presence of an increased frequency of islet-reactive CD4 T cells

17 June 2018

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To B or not to B: (anti)bodies of evidence on the crime scene of type 1 diabetes?

17 June 2018

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Inhibition of Fas Ligand in NOD Mice Unmasks a Protective Role for IL-10 against Insulitis Development

17 June 2018

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Age of islet autoantibody appearance and mean levels of insulin, but not GAD or IA-2 autoantibodies, predict age of diagnosis of type 1 diabetes: diabetes autoimmunity study in the young

17 June 2018

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How does type 1 diabetes develop?: the notion of homicide or β-cell suicide revisited

17 June 2018

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Thymus-specific serine protease controls autoreactive CD4 T cell development and autoimmune diabetes in mice

17 June 2018

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Human Enterovirus RNA in Monthly Fecal Samples and Islet Autoimmunity in Norwegian Children With High Genetic Risk for Type 1 Diabetes

17 June 2018

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Prognostic performance of metabolic indexes in predicting onset of type 1 diabetes

17 June 2018

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The association between the PTPN22 1858C>T variant and type 1 diabetes depends on HLA risk and GAD65 autoantibodies

17 June 2018

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Enteroviruses in the pathogenesis of type 1 diabetes

17 June 2018

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Thymus-specific deletion of insulin induces autoimmune diabetes

17 June 2018

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17 June 2018

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Do non-HLA genes influence development of persistent islet autoimmunity and type 1 diabetes in children with high-risk HLA-DR,DQ genotypes?

17 June 2018

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Human regulatory T cells: role in autoimmune disease and therapeutic opportunities

17 June 2018

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Extreme genetic risk for type 1A diabetes in the post-genome era

17 June 2018

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Protein tyrosine phosphatase PTPN22 in human autoimmunity

17 June 2018

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The postnatal maternal environment influences diabetes development in nonobese diabetic mice

17 June 2018

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Autoantibodies in diabetes

17 June 2018

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Environmental triggers and determinants of type 1 diabetes

17 June 2018

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Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice

17 June 2018

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Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health

17 June 2018

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A comprehensive guide to antibody and T-cell responses in type 1 diabetes.

17 June 2018

1 reference

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Acceleration of type 1 diabetes mellitus in proinsulin 2-deficient NOD mice

17 June 2018

1 reference

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The rise of childhood type 1 diabetes in the 20th century.

17 June 2018

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Failure to censor forbidden clones of CD4 T cells in autoimmune diabetes.

17 June 2018

1 reference

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Humoral beta-cell autoimmunity in relation to HLA-defined disease susceptibility in preclinical and clinical type 1 diabetes

17 June 2018

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17 June 2018

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Cytomegalovirus in autoimmunity: T cell crossreactivity to viral antigen and autoantigen glutamic acid decarboxylase

17 June 2018

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A disease-associated cellular immune response in type 1 diabetics to an immunodominant epitope of insulin

17 June 2018

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17 June 2018

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Early expression of antiinsulin autoantibodies of humans and the NOD mouse: evidence for early determination of subsequent diabetes

17 June 2018

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Major Histocompatibility Complex Class II Molecules Can Protect from Diabetes by Positively Selecting T Cells with Additional Specificities

17 June 2018

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Major Histocompatibility Complex–linked Control of Autoimmunity

17 June 2018

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A mechanism for the major histocompatibility complex-linked resistance to autoimmunity

17 June 2018

1 reference

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The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes.

17 June 2018

1 reference

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Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus.

17 June 2018

1 reference

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Ketoacidosis at diagnosis is predictive of lower residual beta-cell function and poor metabolic control in type 1 diabetes

17 June 2018

1 reference

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Glutamate decarboxylase-, insulin-, and islet cell-antibodies and HLA typing to detect diabetes in a general population-based study of Swedish children

17 June 2018

1 reference

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Islet-cell antibodies in diabetes mellitus with autoimmune polyendocrine deficiencies

17 June 2018

1 reference

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Type I diabetes mellitus. A chronic autoimmune disease

17 June 2018

1 reference

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Type-I diabetes: a chronic autoimmune disease of human, mouse, and rat.

17 June 2018

1 reference

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Materno-Fetal Transfer of Preproinsulin Through the Neonatal Fc Receptor Prevents Autoimmune Diabetes

17 June 2018

1 reference

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Young children (<5 yr) and adolescents (>12 yr) with type 1 diabetes mellitus have low rate of partial remission: diabetic ketoacidosis is an important risk factor

31 August 2018

1 reference

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Incidence and trends of childhood Type 1 diabetes worldwide 1990-1999.

31 August 2018

1 reference

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Generalized resistance to thymic deletion in the NOD mouse; a polygenic trait characterized by defective induction of Bim.

31 August 2018

1 reference

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Remapping the insulin gene/IDDM2 locus in type 1 diabetes

31 August 2018

1 reference

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Clinical characteristics of children diagnosed with type 1 diabetes through intensive screening and follow-up

31 August 2018

1 reference

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Maternal immunity to insulin does not affect diabetes risk in progeny of non obese diabetic mice

31 August 2018

1 reference

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Proinsulin expression by Hassall's corpuscles in the mouse thymus.

31 August 2018

1 reference

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Autoimmune diabetes and the circle of tolerance

31 August 2018

1 reference

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Th1 to Th2 cytokine shifts in nonobese diabetic mice: sometimes an outcome, rather than the cause, of diabetes resistance elicited by immunostimulation.

31 August 2018

1 reference

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IA-2 antibodies--a sensitive marker of IDDM with clinical onset in childhood and adolescence. Childhood Diabetes in Finland Study Group.

31 August 2018

1 reference

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Genetic effects on age-dependent onset and islet cell autoantibody markers in type 1 diabetes

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5266674

Proinsulin-Specific, HLA-DQ8, and HLA-DQ8-Transdimer–Restricted CD4+T Cells Infiltrate Islets in Type 1 Diabetes

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5266674

Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope

3 December 2018

1 reference

12 December 2020

Autoantibodies associated with Type I diabetes mellitus persist after diagnosis in children

1 reference

12 December 2020

Elimination of maternally transmitted autoantibodies prevents diabetes in nonobese diabetic mice

1 reference

12 December 2020

High familial risk and genetic susceptibility in early onset childhood diabetes

1 reference

12 December 2020

Autoantibody appearance and risk for development of childhood diabetes in offspring of parents with type 1 diabetes: the 2-year analysis of the German BABYDIAB Study

1 reference

12 December 2020

Development of type 1 diabetes despite severe hereditary B-cell deficiency

1 reference

12 December 2020

Transgenic insulin (B:9-23) T-cell receptor mice develop autoimmune diabetes dependent upon RAG genotype, H-2g7 homozygosity, and insulin 2 gene knockout

1 reference

12 December 2020

A defect in central tolerance in NOD mice

1 reference

12 December 2020

Insulin expression levels in the thymus modulate insulin-specific autoreactive T-cell tolerance: the mechanism by which the IDDM2 locus may predispose to diabetes

1 reference

12 December 2020

Defective central tolerance induction in NOD mice: genomics and genetics

1 reference

12 December 2020

Markedly reduced rate of diabetic ketoacidosis at onset of type 1 diabetes in relatives screened for islet autoantibodies

1 reference

12 December 2020

Posttranslational Modification of HLA-DQ Binding Islet Autoantigens in Type 1 Diabetes

1 reference

12 December 2020

Disease-associated autoantibodies during pregnancy and at birth in families affected by type 1 diabetes

1 reference

12 December 2020

Concentration of insulin autoantibodies at onset of type I diabetes. Inverse log-linear correlation with age

1 reference

12 December 2020

Differences in risk of insulin-dependent diabetes in offspring of diabetic mothers and diabetic fathers

1 reference

12 December 2020

Human enterovirus infections in children at increased risk for type 1 diabetes: the Babydiet study

1 reference

12 December 2020

10.2174/1573399812666160427104157

Identifiers

DOI

1 reference

7 June 2018

PMC publication ID

5266674

1 reference

7 June 2018

PubMed publication ID

27117244

1 reference

7 June 2018