Estrogen Receptors and Signaling in Fibroids: Role in Pathobiology and Therapeutic Implications. (Q38792320)

PubMed publication ID

6 September 2017

1 reference

title

Estrogen Receptors and Signaling in Fibroids: Role in Pathobiology and Therapeutic Implications (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6344829&resulttype=core&format=json

13 May 2020

Ayman Al-Hendy

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6344829&resulttype=core&format=json

13 May 2020

Mostafa A Borahay

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6344829&resulttype=core&format=json

13 May 2020

Mehmet R Asoglu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6344829&resulttype=core&format=json

13 May 2020

Aymara Mas

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6344829&resulttype=core&format=json

13 May 2020

Sarah Adam

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6344829&resulttype=core&format=json

13 May 2020

Gokhan S Kilic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6344829&resulttype=core&format=json

13 May 2020

publication date

20 November 2016

1 reference

PubMed publication ID

27872195

6 September 2017

published in

Reproductive Sciences

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6344829&resulttype=core&format=json

13 May 2020

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6344829&resulttype=core&format=json

13 May 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6344829&resulttype=core&format=json

13 May 2020

page(s)

1235-1244

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6344829&resulttype=core&format=json

Incidence, aetiology and epidemiology of uterine fibroids

13 May 2020

cites work

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Characterization of uterine leiomyomas by whole-genome sequencing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

The role of angiogenic factors in fibroid pathogenesis: potential implications for future therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Changes in tissue inflammation, angiogenesis and apoptosis in endometriosis, adenomyosis and uterine myoma after GnRH agonist therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Estrogen and progesterone receptors: from molecular structures to clinical targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Structure-function relationship of estrogen receptor alpha and beta: impact on human health

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Signaling Pathways in Leiomyoma: Understanding Pathobiology and Implications for Therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Localization of the estrogen receptor locus (ESR) to chromosome 6q25.1 by FISH and a simple post-FISH banding technique.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Estrogen receptors alpha and beta: two receptors of a kind?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Estrogen signaling: a subtle balance between ER alpha and ER beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Nature of functional estrogen receptors at the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Membrane oestrogen receptor alpha signalling to cell functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

DHHC-7 and -21 are palmitoylacyltransferases for sex steroid receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

A transmembrane intracellular estrogen receptor mediates rapid cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Estrogen signaling through the transmembrane G protein-coupled receptor GPR30.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Plasma membrane estrogen receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

The many faces of estrogen signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Role for Hsp90-associated cochaperone p23 in estrogen receptor signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Estrogen response element-dependent regulation of transcriptional activation of estrogen receptors alpha and beta by coactivators and corepressors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Genomic targets of nuclear estrogen receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Mechanisms of estrogen receptor signaling: convergence of genomic and nongenomic actions on target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Estrogen receptors: orchestrators of pleiotropic cellular responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Regulation of the transcriptional activity of c-Fos by ERK. A novel role for the prolyl isomerase PIN1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

The phosphoinositide 3-kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Estrogenic G protein-coupled receptor 30 signaling is involved in regulation of endometrial carcinoma by promoting proliferation, invasion potential, and interleukin-6 secretion via the MEK/ERK mitogen-activated protein kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Minireview: G protein-coupled estrogen receptor-1, GPER-1: its mechanism of action and role in female reproductive cancer, renal and vascular physiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Long-term treatment of uterine fibroids with ulipristal acetate ☆

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Treatment strategies for uterine leiomyoma: the role of hormonal modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Aromatase in endometriosis and uterine leiomyomata

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Increased expression of type I 17beta-hydroxysteroid dehydrogenase enhances in situ production of estradiol in uterine leiomyoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Steroid hormones and leiomyomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Progesterone is essential for maintenance and growth of uterine leiomyoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

High aromatase expression in uterine leiomyoma tissues of African-American women

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Differential expression of G-protein-coupled estrogen receptor-30 in human myometrial and uterine leiomyoma smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Estrogen receptor alpha (ERalpha) phospho-serine-118 is highly expressed in human uterine leiomyomas compared to matched myometrium

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Estrogen-induced changes in IGF-I, Myb family and MAP kinase pathway genes in human uterine leiomyoma and normal uterine smooth muscle cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Gene expression profiling of multiple leiomyomata uteri and matched normal tissue from a single patient

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

17-beta estradiol elicits an autocrine leiomyoma cell proliferation: evidence for a stimulation of protein kinase-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Human uterine smooth muscle and leiomyoma cells differ in their rapid 17beta-estradiol signaling: implications for proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Differential expression of receptor tyrosine kinases (RTKs) and IGF-I pathway activation in human uterine leiomyomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Comparison of human and rat uterine leiomyomata: identification of a dysregulated mammalian target of rapamycin pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Potential link between estrogen receptor-alpha gene hypomethylation and uterine fibroid formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Genome-wide DNA methylation analysis reveals a potential mechanism for the pathogenesis and development of uterine leiomyomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Fibroid growth and medical options for treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Clinical response, vascular change, and angiogenesis in gonadotropin-releasing hormone analogue-treated women with uterine myomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Down-regulation of proliferation and up-regulation of apoptosis by gonadotropin-releasing hormone agonist in cultured uterine leiomyoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Gonadotropin releasing hormone analogue therapy alters signal transduction pathways involving mitogen-activated protein and focal adhesion kinases in leiomyoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

An evidence-based approach to hormonal therapies for premenopausal women with fibroids

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

CCAAT/enhancer binding protein beta regulates aromatase expression via multiple and novel cis-regulatory sequences in uterine leiomyoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

A selective estrogen receptor modulator designed for the treatment of uterine leiomyoma with unique tissue specificity for uterus and ovaries in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

A randomized, controlled clinical trial comparing the effects of aromatase inhibitor (letrozole) and gonadotropin-releasing hormone agonist (triptorelin) on uterine leiomyoma volume and hormonal status.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Aromatase and leiomyoma of the uterus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Selective estrogen receptor modulators (SERMs): mechanisms of anticarcinogenesis and drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Selective oestrogen receptor modulators in prevention of breast cancer: an updated meta-analysis of individual participant data

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Selective estrogen-receptor modulators -- mechanisms of action and application to clinical practice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Pharmacological treatment of uterine fibroids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

A phase II trial of Afimoxifene (4-hydroxytamoxifen gel) for cyclical mastalgia in premenopausal women

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Structure-activity relationships for a family of benzothiophene selective estrogen receptor modulators including raloxifene and arzoxifene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

The role of tamoxifen in the treatment of symptomatic uterine leiomyomata -- a pilot study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Effectiveness of combined GnRH analogue plus raloxifene administration in the treatment of uterine leiomyomas: a prospective, randomized, single-blind, placebo-controlled clinical trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Does raloxifene inhibit the growth of uterine fibroids?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Effects of raloxifene treatment on uterine leiomyomas in postmenopausal women

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Antiproliferative and proapoptotic effects of raloxifene on uterine leiomyomas in postmenopausal women

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Gene therapy and uterine leiomyoma: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Gene therapy of uterine leiomyomas: adenovirus-mediated expression of dominant negative estrogen receptor inhibits tumor growth in nude mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Estrogen metabolite 2-methoxyestradiol induces apoptosis and inhibits cell proliferation and collagen production in rat and human leiomyoma cells: a potential medicinal treatment for uterine fibroids

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Catechol-o-methyltransferase expression and 2-methoxyestradiol affect microtubule dynamics and modify steroid receptor signaling in leiomyoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719116678686

Estrogen receptors (ERalpha/ERbeta) in normal and pathological growth of the human myometrium: pregnancy and leiomyoma

21 January 2018

1 reference

12 December 2020

Molecular bases for the actions of ovarian sex steroids in the regulation of proliferation and apoptosis of human uterine leiomyoma

1 reference

12 December 2020

Tissue differences but limited sex steroid responsiveness of c-fos and c-jun in human fibroids and myometrium

1 reference

12 December 2020

EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF

1 reference

12 December 2020

In situ estrogen synthesized by aromatase P450 in uterine leiomyoma cells promotes cell growth probably via an autocrine/intracrine mechanism

1 reference

12 December 2020

Pre-operative GnRH analogue therapy before hysterectomy or myomectomy for uterine fibroids

1 reference

12 December 2020

ERbeta has nongenomic action in caveolae

1 reference

12 December 2020

p53 Tumor suppressor protein content in human uterine leiomyomas and its down-regulation by 17 beta-estradiol

1 reference

12 December 2020

Selective estrogen receptor modulator and selective progesterone receptor modulator: therapeutic efficacy in the treatment of uterine leiomyoma

1 reference

12 December 2020

Concentration-dependent effects of a selective estrogen receptor modulator raloxifene on proliferation and apoptosis in human uterine leiomyoma cells cultured in vitro

1 reference

12 December 2020

The effect of anastrazole on symptomatic uterine leiomyomata

1 reference

12 December 2020

Update on bazedoxifene: a novel selective estrogen receptor modulator

1 reference

12 December 2020

Treatment of symptomatic uterine leiomyoma with letrozole

1 reference

12 December 2020

Chromosome analysis of 96 uterine leiomyomas

1 reference

12 December 2020

The dynamic structure of the estrogen receptor

1 reference

12 December 2020

Selective estrogen receptor modulators (SERMs) for uterine leiomyomas

1 reference

12 December 2020

Membrane estrogen receptors - is it an alternative way of estrogen action?

1 reference

12 December 2020

1 reference

12 December 2020

Role of the aromatase inhibitor letrozole in the management of uterine leiomyomas in premenopausal women

1 reference

12 December 2020

Aromatase inhibitors for uterine fibroids

1 reference

12 December 2020

Induction of Ovulation with Clomiphene Citrate

1 reference

12 December 2020

Unicellular histogenesis of uterine leiomyomas as determined by electrophoresis by glucose-6-phosphate dehydrogenase

1 reference

12 December 2020

Expression of the CYP19 gene and its product aromatase cytochrome P450 in human uterine leiomyoma tissues and cells in culture

1 reference

12 December 2020

Expression of connexin-43 in human myometrium and leiomyoma

1 reference

12 December 2020

Rapid regression of uterine leiomyomas in response to daily administration of gonadotropin-releasing hormone antagonist

1 reference

12 December 2020

Comparative Messenger Ribonucleic Acid Analysis of Immediate Early Genes and Sex Steroid Receptors in Human Leiomyoma and Healthy Myometrium

1 reference

12 December 2020

Treatment of uterine leiomyomas with luteinizing hormone-releasing hormone antagonist Cetrorelix

1 reference

12 December 2020

Human estrogen receptor beta-gene structure, chromosomal localization, and expression pattern

1 reference

12 December 2020

Up-regulation by progesterone of proliferating cell nuclear antigen and epidermal growth factor expression in human uterine leiomyoma

1 reference

12 December 2020

Cell membrane and nuclear estrogen receptors (ERs) originate from a single transcript: studies of ERalpha and ERbeta expressed in Chinese hamster ovary cells

1 reference

12 December 2020

Identifiers

DOI

10.1177/1933719116678686

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6344829&resulttype=core&format=json

13 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6344829&resulttype=core&format=json

13 May 2020

PubMed publication ID

27872195

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6344829&resulttype=core&format=json